Caspase-14 antibody

Principal name

Caspase-14 antibody

Alternative names for Caspase-14 antibody

CASP-14, CASP14

SwissProt ID

O89094 (Mouse), P31944 (Human)

Gene ID

23581 (CASP14), 12365 (Casp14)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Caspase-14 antibody

Caspases are a family of cysteine proteases that play key roles in apoptosis. The precursor form of all caspaes is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunits, which associate into a2b2 tetramers to form the active enzyme.
Caspase 14 also known as Mini ICE (MICE) is a member of the peptidase family C14 that has three potential isoforms. The pro form of Caspase 14 is approximately 29 kD. This caspase may be involved in the death receptor and granzyme B apoptotic pathways. Caspase 14 functions as downstream signal transducer of cell death that can be suppressed by retinoic acid. Caspase 14 becomes activated after granzyme B, Caspase 8, and Caspase 10 cleavage into large p18 and small p10 subunits. This caspase has been shown to associate with the large prodomain caspases, including Caspase 1, Caspase 2, Caspase 4, Caspase 8, and Caspase 10.
Its high expression in embryonic tissues and limited expression in adult tissues suggests that it may have a role in ontogenesis.

General readings

1. Pistritto, G., et al., Cell Death Differ. 9, 995-1006 (2002).
Clone 1-71 is used in this reference.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Caspase-14 antibody

  Rabbit Polyclonal Caspase-14 Antibody  
Western blot analysis of caspase-14 in Jurkat cell lysate in the (A) absence or (B) presence of blocking peptide with caspase-14 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-14 antibody

  Rabbit polyclonal antibody to Caspase 14 (caspase 14, apoptosis-related cysteine peptidase)  
Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA308792 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-14 antibody

  Rabbit polyclonal Caspase 14 (p10, Cleaved-Lys222) antibody  
Western blot analysis of extracts from COLO cells and HepG2 cells, using Caspase 14 (p10, Cleaved-Lys222) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-14 antibody

  Mouse Monoclonal Caspase-14 Antibody (70A1426)  
Western Blot: Caspase 14 Antibody (70A1426) [NB100-56718] - Western blot analysis for Caspase-14 using NB100-56718 at 2 ug/ml dilution against 10 ug of mouse spleen cell lysate. Mouse 70A1426 Purified Hu, Ms F, WB
0.2 ml / €325.00
  OriGene Technologies, Inc.

Caspase-14 antibody

  Rabbit Polyclonal Anti-CASP14 Antibody  
Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-4: Jurkat cells, A431 cells, A549 cells, A375 cells, Primary antibody: (CASP14 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-14 antibody

Western blot analysis of caspase-14 expression in ZR75-1 (Lane 1) and MCF-7 (Lane 2) using AM20291AF-N Caspase 14 antibody. Mouse IgG1 1-71 Azide Free Hu ICC/IF, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

Caspase-14 (C-term) antibody

Immunohistochemical staining of human liver with Rabbit anti caspase-14 (AP05590PU-N) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Caspase-14 (C-term) antibody

AP07689PU-N Caspase-14 antibody staining of Formalin-Fixed Paraffin-Embedded Human Skin at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Caspase-14 antibody

Skin stained in IHC-P with Caspase-14 antibody Rabbit Purified Hu E, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CASP14 - human gene knockout kit via CRISPR

CASP14 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CASP14 - human gene knockout kit via CRISPR

CASP14 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CASP14 - human gene knockout kit via CRISPR

CASP14 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CASP14 - human gene knockout kit via CRISPR

CASP14 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Casp14 - mouse gene knockout kit via CRISPR

Casp14 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Casp14 - mouse gene knockout kit via CRISPR

Casp14 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Casp14 - mouse gene knockout kit via CRISPR

Casp14 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Casp14 - mouse gene knockout kit via CRISPR

Casp14 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CASP14 (mGFP-tagged) - Human caspase 14, apoptosis-related cysteine peptidase (CASP14), 200 uL, >10^7 TU/mL

Lenti ORF particles, CASP14 (mGFP-tagged) - Human caspase 14, apoptosis-related cysteine peptidase (CASP14), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, CASP14 (Myc-DDK tagged) - Human caspase 14, apoptosis-related cysteine peptidase (CASP14) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CASP14 (Myc-DDK tagged) - Human caspase 14, apoptosis-related cysteine peptidase (CASP14) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Casp14 (GFP-tagged) - Mouse caspase 14 (Casp14), 200 uL, >10^7 TU/mL

Lenti ORF particles, Casp14 (GFP-tagged) - Mouse caspase 14 (Casp14), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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