Caspase-6 antibody

Principal name

Caspase-6 antibody

Alternative names for Caspase-6 antibody

CASP-6, CASP6, MCH2, MCH-2, Apoptotic protease Mch-2

SwissProt ID

O08738 (Mouse), O35397 (Rat), P55212 (Human), Q3T0P5 (Bovin)

Gene ID

839 (CASP6), 12368 (Casp6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Rb (Rabbit), Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of Caspase-6 antibody

Caspase-6 (Cysteine-Requiring Aspartate Proteases) is part of a family of intracellular cysteine proteases that cleave their substrates after aspartic acid residues. These proteases play an integral role in inducing apoptosis in cells. Procaspase-6 (Mch2), a member of the ICE/ced-3 subfamily, is an inactive proenzyme that is activated to form caspase-6 by proteolytic cleavage at certain aspartic acid residues. During cleavage, the N-terminal is removed and the proenzyme is converted into a large (p18) and small (p11) subunits. Caspase-6 has two isoforms produced by alternative splicing. Over-expression of the isoform of caspase-6 without its prodomain can induce apoptosis. The isoform does not seem to display proteolytic activity. Together with caspases-3 and -7, the isoform of caspase-6 is classified as an effector/execution caspase. Caspase-3, caspase-8 and caspase-10 can cleave procaspase-6. Active caspase-6 cleaves several other proteins such as lamins, NuMa and Keratin 18. A possible cleavage of caspases-8 and -10 in cytochrome-C dependent apoptosis was reported recently.

General readings

Nakamura,T., (2004) J. Biol. Chem. 279 (1), 626-634

20 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Caspase-6 antibody

  Rabbit polyclonal Caspase 6 (Cleaved-Asp179) antibody  
Western blot analysis of extracts from 293 cells, treated with Etoposide (25uM, 60mins), using Caspase 6 (cleaved-Asp179) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Rabbit polyclonal Caspase 6 (Ser257) antibody(Phospho-specific)  
Western blot analysis of extracts from 293 cells treated with Etoposide (25uM, 60min), using Caspase 6 (Phospho-Ser257) antibodyThe lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Rabbit polyclonal Caspase 6 (Ab-257) antibody  
Western blot analysis of extracts from A431 cells, using Caspase 6 (Ab-257) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Rabbit polyclonal Caspase 6 (Cleaved-Asp162) antibody  
Western blot analysis of extracts from HeLa cells, treated with etoposide (25µM, 1hour), using Caspase 6 (cleaved-Asp162) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Anti-CASP6 Rabbit Polyclonal Antibody  
Predicted band size: 33 kDa . Positive control: Mouse stomach tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 40 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Anti-CASP6 Rabbit Polyclonal Antibody  
Predicted band size: 33 kDa . Positive control: Mouse stomach tissue lysate. Recommended dilution: 1/50-500. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/50 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Rabbit anti-CASP6 Polyclonal Antibody  
Western blot analysis of extracts of Jurkat cell lines, using CASP6 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Rabbit Polyclonal Caspase-6 Antibody  
Western Blot: Caspase 6 Antibody [TA336324] - analysis of Caspase-6 using Caspase-6 polyclonal antibody. Recombinant catalytically active caspase-6was western blotted with Active/Cleaved Caspase-6 antibody. Theantibody detected both the large and small su Rabbit Purified Can, Hu, Ms, Rt IP, P, WB
50 µl / €334.00
  OriGene Technologies, Inc.

Caspase-6 antibody

  Rabbit Polyclonal Anti-Caspase 6 (Cleaved-Asp179) Antibody  
Western blot analysis of Caspase 6 (Cleaved-Asp179) expression in Hela cells Rabbit IgG Purified Hu, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

Caspase-6 (1-293) antibody

Immunocytochemical detection of Caspase-6 on acetone fixed HEp-II cells with AM26617AF-N Mouse IgG1 3E8 Azide Free Hu, Rt ICC/IF, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

Caspase-6 (active) antibody

Caspase-6 Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €450.00
  Acris Antibodies GmbH

Caspase-6 antibody

Western blot analysis of Caspase-6 expression rat kidney tissue lysate. Both full length and the cleaved large fragment have been detected. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Caspase-6 pSer257 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using Caspase 6 (Phospho-Ser257) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

Caspase-6 pSer257 antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using Caspase 6 (Phospho-Ser257) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

Caspase-6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Caspase 6 (Ab-257) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

Caspase-6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Caspase 6 (Ab-257) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

Caspase-6 (cleaved) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 6 (Cleaved-Asp162) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Caspase-6 (cleaved) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 6 (Cleaved-Asp162) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Caspase-6 (cleaved) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 6 (Cleaved-Asp162) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Caspase-6 (cleaved) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 6 (Cleaved-Asp162) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

20 Item(s)

per page
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