Cathepsin A antibody

Principal name

Cathepsin A antibody

Alternative names for Cathepsin A antibody

Carboxypeptidase L, Carboxypeptidase C, CTSA, PPGB, PPCA, Lysosomal protective protein,Protective protein for beta-galactosidase

SwissProt ID

P10619 (Human), P16675 (Mouse), Q3MI05 (Bovin)

Gene ID

5476 (CTSA), 19025 (Ctsa)

Available reactivities

E. coli (Escherichia coli), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Chicken, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of Cathepsin A antibody

Lysosomal protective protein/cathepsin A (PPCA) is a lysosomal serine carboxypeptidase that forms an intralysosomal enzyme complex with ?galactosidase and neuraminidase (NEU1). PPCA is synthesized as a 54 kDa precursor/zymogen, and proteolytically cleaved in the lysosome into a catalytically active 32 and 20 kDa two chain enzyme. The enzyme has cathepsin A activity at acidic pH but maintains also a deamidase/esterase activity at neutral pH. Furthermore, the human enzyme, purified from platelets and lymphocytes, has been shown to function on the inactivation of selected neuropeptides, like substance P, oxytocin, and endothelin I. The autosomal recessive genetic deficiency of PPCA causes galactosialidosis, a neurodegenerative lysosomal storage disorder, resulting in the secondary deficiencies of ?galactosidase and NEU1.

General readings

Seyrantepe V., et al. (2008) Circulation. 117:1973-1981.Hiraiwa M., et al. (1999) Cell Mol Life Sci. 56:894-907.

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cathepsin A antibody

Western blot analysis of extracts from Jurkat cells and 293 cells, treated with etoposide (25uM, 1hour), using PPGB (32k, Cleaved-Arg326) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cathepsin A antibody

Western blot analysis of extracts of various cell lines, using CTSA antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cathepsin A (N-term) antibody

CTSA antibody (N-term) (Cat. #AP51129PU-N) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CTSA antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Cathepsin A antibody

Western Blot analysis of CTSA expression in transfected 293T cell line (H00005476-T01) by CTSA MaxPab polyclonal antibody.

Lane 1: PPGB transfected lysate(52.8 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Cathepsin A antibody

Cathepsin A Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Cathepsin A (cleaved) antibody

Western blot analysis of extracts from 293/Jurkat cells, treated with etoposide 25uM 1h, using PPGB (32k,Cleaved-Arg326) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

Cathepsin A (cleaved) antibody

Western blot analysis of extracts from 293/Jurkat cells, treated with etoposide 25uM 1h, using PPGB (32k,Cleaved-Arg326) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

Cathepsin A antibody

Western blot analysis of Cathepsin A 32k expression in HepG2 (A); mouse kidney (B); rat liver (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Cathepsin A antibody

Western blot analysis of Cathepsin A 32k expression in HepG2 (A); mouse kidney (B); rat liver (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Cathepsin A antibody

Western blot analysis of Cathepsin A 32k expression in HepG2 (A); mouse kidney (B); rat liver (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Cathepsin A antibody

Immunohistochemistry-Paraffin: Cathepsin A Antibody [NBP1-89728] - Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cathepsin A (transcript variant 1)

Cathepsin A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Cathepsin A (transcript variant 1)

Cathepsin A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Cathepsin A (24-474, His-tag)

Cathepsin A Mouse Purified > 90 % by SDS - PAGE
0.25 mg / €940.00
  Acris Antibodies GmbH

Cathepsin A (24-474, His-tag)

Cathepsin A Mouse Purified > 90 % by SDS - PAGE
50 µg / €300.00
  Acris Antibodies GmbH

Cathepsin A

Cathepsin A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

Cathepsin A

Cathepsin A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

PPGB 293T Cell Transient Overexpression Lysate(Denatured)

PPGB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

18 Item(s)

per page
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