Cathepsin K antibody

Principal name

Cathepsin K antibody

Alternative names for Cathepsin K antibody

Cathepsin O, Cathepsin X, Cathepsin O2, CTSK, CTSO, CTSO2

SwissProt ID

O35186 (Rat), P43235 (Human), P55097 (Mouse), Q5E968 (Bovin), Q90686 (Chick)

Gene ID

1513 (CTSK), 29175 (Ctsk)

Available reactivities

Hu (Human), Chk (Chicken), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey), Hst (Hamster), Eq (Equine), GP (Guinea Pig), Gt (Goat), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Cathepsin K antibody

Cathepsin family of proteases contains several diverse classes of enzymes. The cysteine protease class comprises cathepsin B, H, K, L, O, and S. The aspartyl protease class contains cathepsin D and E. Cathepsin G belongs to the serine protease class. Cathepsins are involved in various cellular events such as peptide biosynthesis, protein degradation, and apoptosis.
Cathepsin K expression is highest in bone, cartilage, and skeletal muscle. Cathepson K is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in the gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

General readings

Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, Nishikawa K, Latz E, Golenbock DT, Aoki K, Ohya K, Imai Y, Morishita Y, Miyazono K, Kato S, Saftig P, Takayanagi H
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis
Science. 2008 Feb 1;319(5863):624-7
PMID: 18239127

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cathepsin K antibody

Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Rabbit IgG Purified Chk, Hu, Ms, Por, Rb, Rt IP, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

Cathepsin K antibody

Formalin-Fixed, Paraffin-Embedded Human Kidney stained with Cadherin-K Antibody Cat.-No AM20875PU-N (Clone 2F1) at 5 µg/ml after heat-induced antigen retrieval. Mouse IgG2a 2F1 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Cathepsin K antibody

TA303361 (1µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cathepsin K antibody

Anti-CTSK / Cathepsin K antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Rabbit IgG Purified Hu, Ms, Rt IP, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

Cathepsin K antibody

WB Suggested Anti-CTSK Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Liver Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Cathepsin K antibody

Cathepsin K Mouse IgG1 182-12G5 Purified Hu WB
0.1 mg / €360.00
  Acris Antibodies GmbH

Cathepsin K Control Peptide

Cathepsin K Purified
50 µg / €190.00
  Acris Antibodies GmbH

Cathepsin K antibody

Figure 1. Western blot analysis of Cathepsin K expression in MCF7 cell lysate. Rabbit Aff - Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Cathepsin K Control Peptide

Cathepsin K Purified
50 µg / €190.00
  Acris Antibodies GmbH

Cathepsin K antibody

Western blot analysis of Cathepsin K with rat kidney tissue lysate. Rabbit Aff - Purified Chk, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Cathepsin K antibody

Western blot analysis of CTSK antibody (Center R222) (AP17260PU-N) in A375 cell line lysates (35 µg/lane). CTSK (arrow) was detected using the purified Pab. Rabbit Aff - Purified Bov, Hu, Mky, Por, Rb F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Cathepsin K (Center) antibody

Formalin fixed and paraffin embedded human skeletal muscle stained with CTSK Antibody (Center) Cat.-No AP51131PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Cathepsin K antibody

Western Blot analysis of CTSK expression in transfected 293T cell line (H00001513-T01) by CTSK MaxPab polyclonal antibody.

Lane 1: CTSK transfected lysate(36.19 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Cathepsin K antibody

Western Blot analysis of CTSK expression in transfected 293T cell line (H00001513-T01) by CTSK MaxPab polyclonal antibody.

Lane 1: CTSK transfected lysate(37.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Cathepsin K antibody

Immunoperoxidase of monoclonal antibody to CTSK on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse IgG2a 2F1 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cathepsin K antibody

Detection limit for recombinant GST tagged CTSK is approximately 3ng/ml as a capture antibody. Mouse IgG2b 1B11 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cathepsin K antibody

CTSK polyclonal antibody ( Cat # PAB7476 ) ( 1 µg/ml ) staining of human lung lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Cathepsin K antibody

Western blot analysis of CTSK expression in rat kidney tissue lysate. Rabbit Chk, Hu, Ms, Rb, Rt C, IP, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

Cathepsin K antibody

Western blot analysis of Ctsk expression in MCF-7 cell lysate. Rabbit Hu, Ms, Rt C, IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Cathepsin K antibody

Human Fetal liver; WB Suggested Anti-CTSK Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Liver; CTSK antibody - middle region (ARP60949_P050) in Human Fetal liver cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

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