CBFA2T2 antibody

Principal name

CBFA2T2 antibody

Alternative names for CBFA2T2 antibody

EHT, MTGR1, MTG8-like protein, MTG8-related protein 1, ETO homologous on chromosome 20, p85, Myeloid translocation-related protein 1

SwissProt ID

O43439 (Human), O70374 (Mouse), Q96L00 (Human), Q9IAB2 (Xenla)

Gene ID

12396 (Cbfa2t2), 9139 (CBFA2T2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Chk (Chicken), Eq (Equine)

Available hosts

Rabbit, Sheep, Mouse, Rat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CBFA2T2 antibody

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. CBFA2T2 binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length tures of only three have been described.

General readings

Yoshikawa,T., et al., (er) Gene Expr. Patterns (2005) In press

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CBFA2T2 antibody

Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308048 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CBFA2T2 (N-term) antibody

CBFA2T2 Antibody (N-term) (Cat. #TA324594) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CBFA2T2 antibody detected the CBFA2T2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CBFA2T2 antibody

WB Suggested Anti-CBFA2T2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysate; CBFA2T2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CBFA2T2 antibody

WB Suggested Anti-CBFA2T2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CBFA2T2 antibody

CBFA2T2 Rat IgG2c KT42 Aff - Purified Ms IP, WB
1 mg / €910.00
  Acris Antibodies GmbH

CBFA2T2 antibody

CBFA2T2 Rat IgG2c KT42 Aff - Purified Ms IP, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

CBFA2T2 antibody

CBFA2T2 Rat IgG2c KT42 Aff - Purified Ms IP, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CBFA2T2 antibody

CBFA2T2 Sheep IgG Purified Hu WB
0.25 mg / €360.00
  Acris Antibodies GmbH

CBFA2T2 antibody

Immunofluorescence of purified MaxPab antibody to CBFA2T2 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

Western Blot analysis of CBFA2T2 expression in transfected 293T cell line by CBFA2T2 monoclonal antibody (M05), clone 3A2.

Lane 1: CBFA2T2 transfected lysate(63.9 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 3A2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

CBFA2T2 Mouse IgG2b 2H8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

CBFA2T2 Mouse IgG2b 3G8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

Western Blot analysis of CBFA2T2 expression in transfected 293T cell line by CBFA2T2 monoclonal antibody (M15), clone 2C10.

Lane 1: CBFA2T2 transfected lysate(63.9 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2b 2C10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

CBFA2T2 Mouse IgG2a 3H3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

CBFA2T2 Rat IgG2c KT42 Ms IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CBFA2T2 antibody

Mouse Brain; WB Suggested Anti-Cbfa2t2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Mouse Brain; Cbfa2t2 antibody - middle region (ARP37524_P050) in Mouse Brain cells using Western Blot Rabbit Aff - Purified Ms WB
50 µg / €350.00
  AVIVA Systems Biology

CBFA2T2 antibody

Mouse NIH-3T3; WB Suggested Anti-CBFA2T2H Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: NIH/3T3 cell lysate; CBFA2T2H antibody - middle region (ARP37525_P050) in Mouse NIH-3T3 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CBFA2T2 antibody

Human HepG2; WB Suggested Anti-CBFA2T2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate. CBFA2T2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells.; CBFA2T2 antibody - N-terminal region (ARP38558_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CBFA2T2 antibody

Human Thymus; WB Suggested Anti-CBFA2T2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; CBFA2T2 antibody - middle region (ARP38559_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CBFA2T2 antibody

CBFA2T2 Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

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