CBL / RNF55 antibody

Principal name

CBL / RNF55 antibody

Alternative names for CBL / RNF55 antibody

RING finger protein 55, CBL2, c-CBL, E3 ubiquitin-protein ligase CBL, Signal transduction protein CBL, Proto-oncogene c-CBL, Casitas B-lineage lymphoma proto-oncogene

SwissProt ID

P22681 (Human), P22682 (Mouse)

Gene ID

867 (CBL), 12402

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Chk (Chicken)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Flow Cytometry (F)

Background of CBL / RNF55 antibody

Cbl (also designated the c-Cbl proto-oncogene, E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene and RING finger protein 55) has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis. The c-Cbl gene product has been identified as a cytoplasmic protein with apparent DNA binding and dimerization domains characteristic of transcription factors. A single c-Cbl locus termed CBL2 has been mapped to human chromosome 11q23. This region of chromosome 11 is involved in translocations and deletions in a broad range of leukemias; c-Cbl has been found to be translocated from chromosome 11 in leukemias with either t(4;11) or t(11;14) abnormalities. Two proteins related to c-Cbl have been identified as Cbl-b (RING finger protein 56) and Cbl-3 (RING finger protein 57). Cbl-b has a proline-rich domain, a nuclear localization signal, a C3HC4 zinc finger and a putative leucine zipper. Cbl-b is expressed in normal and malignant mammary epithelial cells, various normal tissues and hematopoietic tissue and cell lines. Data suggests that Cbl-b encodes a protein that can interact with signal transduction proteins to regulate their function or be regulated by them.

General readings

1. Fernandes MS  et al. Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism. J Biol Chem 285:32596-605 (2010). WB .

  1. Quick-Filters:
  2. Highly Validated (1)

Items 1 to 20 of 72 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CBL / RNF55 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using C-CBL mouse mAb with DAB staining. Mouse IgG1 3B12 Ascites Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CBL / RNF55 (C-term) antibody

TA302756 staining (2µg/ml) of 3T3 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
20 µg / €200.00
  Acris Antibodies GmbH

CBL / RNF55 (C-term) antibody

TA302756 staining (2µg/ml) of 3T3 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBL / RNF55 antibody

Western blot analysis of cbl in Daudi cell lysate with cbl antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBL / RNF55 antibody

Western blot analysis of extracts from HepG2 cells, treated with Na2VO3 (0.3nM, 40mins), using CBL (Ab-674) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CBL / RNF55 antibody

Western blot analysis of CBL expression in Na2VO3 treated HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CBL / RNF55 antibody

Immunohistochemistry (IHC) analyzes of CBL antibody (Cat.-No.: AP06426PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CBL / RNF55 antibody

Immunohistochemistry (IHC) analyzes of CBL antibody (Cat.-No.: AP06427PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CBL / RNF55 antibody

Immunohistochemistry (IHC) analyzes of CBL antibody (Cat.-No.: AP06505PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CBL / RNF55 pTyr700 antibody

Figure 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Cbl pTyr700 Antibody AP08042PU Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

CBL / RNF55 pTyr700 antibody

Figure 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-Cbl pTyr700 Antibody AP08042PU Rabbit Aff - Purified Hu ICC/IF, P, WB
50 µl / €240.00
  Acris Antibodies GmbH

CBL / RNF55 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue
using c-Cbl Antibody Rabbit Aff - Purified Hu P
0.1 ml / €270.00
  Acris Antibodies GmbH

CBL / RNF55 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue
using c-Cbl Antibody Rabbit Aff - Purified Hu P
50 µl / €230.00
  Acris Antibodies GmbH

CBL / RNF55 Control Peptide

CBL / RNF55
50 µg / €160.00
  Acris Antibodies GmbH

CBL / RNF55 pTyr674 antibody

Western blot analysis of extracts from HepG2 cells treated with Na2VO3 using Phospho-CBL (Tyr674) antibody AP55898PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

CBL / RNF55 pTyr674 antibody

Western blot analysis of extracts from HepG2 cells treated with Na2VO3 using Phospho-CBL (Tyr674) antibody AP55898PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

CBL / RNF55 antibody

CBL / RNF55 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CBL / RNF55 antibody

Western Blot analysis of CBL expression in transfected 293T cell line (H00000867-T01) by CBL MaxPab polyclonal antibody.

Lane 1: CBL transfected lysate(99.66 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CBL / RNF55 antibody

CBL / RNF55 Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CBL / RNF55 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between CBL and PLCG1 HeLa cells were stained with anti-CBL rabbit purified polyclonal 1:1200 and anti-PLCG1 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Items 1 to 20 of 72 total

per page
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  • LinkedIn