CBX1 antibody

Principal name

CBX1 antibody

Alternative names for CBX1 antibody

Chromobox protein homolog 1, M31, Heterochromatin protein p25, HP1Hsbeta, p25beta, HP1-beta, HP1 beta, Heterochromatin protein 1 homolog beta, Modifier 1 protein

SwissProt ID

P83916 (Human), P83917 (Mouse)

Gene ID

10951 (CBX1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Rt (Rat), Ze (Zebrafish), African clawed frog, Mky (Monkey), Por (Porcine), Eq (Equine), Rb (Rabbit)

Available hosts

Rat, Rabbit, Goat, Mouse

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), ChIP assay (ChIP), Immunofluorescence (IF)

Background of CBX1 antibody

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol. 2003 Nov;23(22):8363-76. PMID: 14585993

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CBX1 antibody

TA303064 (0.3µg/ml) staining of A431 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX1 antibody

WB Suggested Anti-CBX1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: OVCAR-3 cell lysateCBX1 is supported by BioGPS gene expression data to be expressed in OVCAR3 Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CBX1 antibody

WB Suggested Anti-CBX1 Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX1 antibody

Immunofluorescence analysis of Hela cells using CBX1 antibody Cat.-No AM06468SU-N (green). Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 5A3 Ascites Hu, Mky E, F, ICC/IF, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

CBX1 antibody

Immunohistochemistry on paraffin sections: Human brain cortex stained with AM26739PU-N. Mouse IgG1 1MOD-1A9 Purified Hu, Ms, Por P
0.1 mg / €440.00
  Acris Antibodies GmbH

CBX1 antibody

Detection of Human HP1 beta in HeLa whole cell lysate using Rabbit anti Human HP1 beta (AP05722PU-N) Goat IgG Purified Hu, Ms WB
50 µg / €330.00
  Acris Antibodies GmbH

CBX1 (69-81) antibody

Figure 1. Immunohistochemical analysis of Formalin-Fixed Paraffin-Embedded Human Placenta tissue using AP08785PU-N at 2.5 µg/ml. Goat IgG Aff - Purified Bear, Bt, Can, Elephant, Hst, Hu, L, Mky, Ms, Op, Platypus, Por, Prim, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CBX1 antibody

Western Blot analysis of CBX1 expression in transfected 293T cell line by CBX1 monoclonal antibody (M01), clone 4E12.

Lane 1: CBX1 transfected lysate(21.4 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 4E12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CBX1 antibody

CBX1 polyclonal antibody ( Cat # PAB6884 ) ( 2.5µg/ml ) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Hu E, P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CBX1 antibody

Western blot was performed on nuclear extracts from HeLa cells ( HeLa NE, 20 µg ) with CBX1 polyclonal antibody ( Cat # PAB14123 ) diluted 1 : 1,000 in TBS-Tween containing 5% skimmed milk.
The expected location of CBX1, CBX3, and CBX5 is indicated on the right.
The HP1 antibody is not specific for CBX1, but also recognizes CBX3 and CBX5. Rabbit Purified Hu WB
50 µg / €470.00
  Abnova Taiwan Corp.

CBX1 antibody

Human OVCAR-3; WB Suggested Anti-CBX1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: OVCAR-3 cell lysate. CBX1 is supported by BioGPS gene expression data to be expressed in OVCAR3.; CBX1 antibody - N-terminal region (ARP34426_P050) in Human OVCAR-3 cells using Western Blot Rabbit Aff - Purified African clawed frog, Can, Chk, Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CBX1 antibody

Human HepG2; WB Suggested Anti-CBX1 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; CBX1 antibody - middle region (ARP34427_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Dros, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

CBX1 ChIP grade antibody

CBX1 Rabbit IgG Aff - Purified Hu ChIP, IF, WB
50 µg / €390.00
  Funakoshi Co., Ltd.

CBX1 antibody

Immunohistochemistry: HP1-Beta Antibody [NB100-2423] - 2.5ug/ml staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CBX1 antibody

Immunofluorescence: CBX1 Antibody (5A3) [NBP1-51595] - Immunofluorescence analysis of Hela cells using CBX1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 5A3 Purified Hu, Mky E, ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CBX1 (transcript variant 1)

CBX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CBX1 (transcript variant 2)

CBX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CBX1 (1-185, His-tag)

CBX1 Human Purified > 85 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

CBX1 (1-185, His-tag)

CBX1 Human Purified > 85 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CBX1

CBX1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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