CBX8 antibody

Principal name

CBX8 antibody

Alternative names for CBX8 antibody

Chromobox protein homolog 8, Polycomb 3 homolog, Rectachrome 1, PC3, RC1

SwissProt ID

Q9HC52 (Human), Q9QXV1 (Mouse)

Gene ID

57332 (CBX8)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Mky (Monkey), Por (Porcine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Luminex (LMNX)

Background of CBX8 antibody

Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.

General readings

Dietrich N, Bracken AP, Trinh E, Schjerling CK, Koseki H, Rappsilber J, Helin K, Hansen KH.
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus.
EMBO J. 2007 Mar 21;26(6):1637-48. Epub 2007 Mar 1.
PMID: 17332741

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CBX8 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-CBX8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA800617) Mouse IgG1 OTI3D1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CBX8 antibody

TA303368 (0.1µg/ml) staining of K562 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

Predicted band size: 43 kDa . Positive control: 231, Hela and A549 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: 231 cell lysate Lane2: Hela cell lysate Lane3: A549 cell lysate Lysates: 40 ug Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

Predicted band size: 43 kDa . Positive control: 231, Hela and A549 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: 231 cell lysate Lane2: Hela cell lysate Lane3: A549 cell lysate Lysates: 40 ug Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 1C7 Capture (TA600302) and 2A5 Detection (TA700302) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI1C7 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 2B2 Capture (TA600303) and 6D9 Detection (TA700304) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI2B2 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 2C8 Capture (TA600304) and 2A5 Detection (TA700302) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI2C8 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 5F3 Capture (TA600305) and 2A5 Detection (TA700302) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI5F3 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 6D9 Capture (TA600306) and 4H3 Detection (TA700305) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI6D9 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 3A11 Capture (TA600307) and 6D9 Detection (TA700304) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI3A11 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 4H3 Capture (TA600308) and 6D9 Detection (TA700304) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI4H3 Purified Hu LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 1C7 Capture (TA600302) and 2A5 Detection (TA700302) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI2A5 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 1C7 Capture (TA600302) and 3D1 Detection (TA700303) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI3D1 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 2B2 Capture (TA600303) and 6D9 Detection (TA700304) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI6D9 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 6D9 Capture (TA600306) and 4H3 Detection (TA700305) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI4H3 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 6D9 Capture (TA600306) and 2B2 Detection (TA700306) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI2B2 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CBX8 antibody

CBX8 Luminex Elisa with 6D9 Capture (TA600306) and 3A11 Detection (TA700307) Antibodies. Substrate used: Recombinant Human CBX8 (LY412158) Mouse IgG1 OTI3A11 Purified Hu LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CBX8 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CBX8 (RC203417, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CBX8. Mouse IgG2b OTI6D9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CBX8 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CBX8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800492) Mouse IgG2b OTI3A11 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CBX8 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CBX8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800493) Mouse IgG1 OTI2B2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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