CCBE1 antibody

Principal name

CCBE1 antibody

Alternative names for CCBE1 antibody

KIAA1983, Collagen and calcium-binding EGF domain-containing protein 1, Full of fluid protein homolog

SwissProt ID

Q3MI99 (Mouse), Q6UXH8 (Human)

Gene ID

147372 (CCBE1), 320924 (Ccbe1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CCBE1 antibody

The lymphatic system comprises a vascular system separate from the cardiovascular system, essential for immune responses, fluid homeostasis and fat absorption. Lymphatic vessels develop in a complex process termed lymphangiogenesis that involves budding, migration and proliferation of lymphatic endothelial progenitor cells. A few genes, such as FLT4, FOXC2 and SOX18, are known to be critically involved in lymph vessel formation in humans.
Lymphedema, lymphangiectasias, mental retardation and unusual facial characteristics define the autosomal recessive Hennekam syndrome. Homozygosity mapping identified a critical chromosomal region containing ccbe1, encoding Collagen and Calcium-Binding EGF-domain-1, a secreted protein which is required for embryonic lymphangiogenesis in zebrafish.
Ccbe1 is not expressed in endothelial cells of lymph vessels, and it may be a component of the extracellular matrix. In zebrafish, ccbe1 expression was observed along the earliest migration routes of endothelial cells that sprout from the posterior cardinal vein and migrate circuitously before developing into lymphatic vessels. ccbe1 might therefore be involved in guidance of these migrating cells.

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CCBE1 antibody

  Rabbit Polyclonal Anti-CCBE1 Antibody  
WB Suggested Anti-CCBE1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CCBE1 antibody

  Rabbit Polyclonal Anti-Ccbe1 Antibody  
WB Suggested Anti-Ccbe1 Antibody; Titration: 1.0 ug/ml; Positive Control: Mouse Kidney Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CCBE1 antibody

Immunofluorescence staining (green) of human foreskin (cryo-section of unfixed tissue) with anti human ccbe1 (dilution 1/50) Cat.-No AP26020PU-N. A) Note specific staining in epidermis (ep) and in scattered cells in the dermis. B) Negative control of a consecutive section. Nuclei counter-stained with Dapi (blue). Specimen provided by Prof. Dr. J. Wilting, Goettingen. Rabbit IgG Purified Hu ICC/IF, WB
0.2 mg / €370.00
  Acris Antibodies GmbH

CCBE1 antibody

Immunofluorescence staining (green) of human foreskin (cryo-section of unfixed tissue) with anti human ccbe1 (dilution 1/50) Cat.-No AP26020PU-N. A) Note specific staining in epidermis (ep) and in scattered cells in the dermis. B) Negative control of a consecutive section. Nuclei counter-stained with Dapi (blue). Specimen provided by Prof. Dr. J. Wilting, Goettingen. Rabbit IgG Purified Hu ICC/IF, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CCBE1 - human gene knockout kit via CRISPR

CCBE1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CCBE1 - human gene knockout kit via CRISPR

CCBE1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CCBE1 - human gene knockout kit via CRISPR

CCBE1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CCBE1 - human gene knockout kit via CRISPR

CCBE1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ccbe1 - mouse gene knockout kit via CRISPR

Ccbe1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CCBE1 overexpression lysate

CCBE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CCBE1 (mGFP-tagged) - Human collagen and calcium binding EGF domains 1 (CCBE1), 200 uL, >10^7 TU/mL

Lenti ORF particles, CCBE1 (mGFP-tagged) - Human collagen and calcium binding EGF domains 1 (CCBE1), 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.

Lenti ORF particles, CCBE1 (Myc-DDK tagged) - Human collagen and calcium binding EGF domains 1 (CCBE1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CCBE1 (Myc-DDK tagged) - Human collagen and calcium binding EGF domains 1 (CCBE1) , 200 uL, >10^7 TU/mL  
200 µl / €890.00
  OriGene Technologies, Inc.

12 Item(s)

per page
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