CCDC40 antibody

Principal name

CCDC40 antibody

Alternative names for CCDC40 antibody

KIAA1640, Coiled-coil domain-containing protein 40

SwissProt ID

Q4G0X9 (Human), Q8BI79 (Mouse)

Gene ID

55036 (CCDC40)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of CCDC40 antibody

Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39.Involvement in disease:Defects in CCDC40 are the cause of primary ciliary dyskinesia type 15 (CILD15) . A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CCDC40 antibody

Western Blot analysis of CCDC40 expression in transfected 293T cell line (H00055036-T01) by CCDC40 MaxPab polyclonal antibody.

Lane 1: CCDC40 transfected lysate(52.58 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CCDC40 antibody

Immunohistochemistry-Paraffin: CCDC40 Antibody [NBP1-82162] - Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in urothelial cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CCDC40

CCDC40 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CCDC40

CCDC40 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CCDC40 293T Cell Transient Overexpression Lysate(Denatured)

CCDC40 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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