CCR10 / GPR2 antibody

Principal name

CCR10 / GPR2 antibody

Alternative names for CCR10 / GPR2 antibody

C-C chemokine receptor type 10, C-C CKR-10, CC-CKR-10, CCR-10, G-protein coupled receptor 2

SwissProt ID

P46092 (Human), Q9JL21 (Mouse)

Gene ID

2826 (CCR10), 12777 (Ccr10)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bt (Bat), Bov (Bovine), Can (Canine), Hst (Hamster), Por (Porcine), Rb (Rabbit), Bear

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Frozen Sections (C)

Background of CCR10 / GPR2 antibody

CCR10, C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene. CCR10 is constitutively expressed in skin melanocytes, fibroblasts, and microvascular endothelial cells, and that it is upregulated by IL1B and TNF. Expression was also detected in T cells, Langerhans cells, and peripheral blood mononuclear cells but not in dendritic cells.By fluorescence in situ hybridization, the GPR2 gene is mapped to 17q21.1-q21.3. CCR10 is the receptor for CCL27. CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation. expression of CCL27 in normal keratinocytes and its strong upregulation in skin lesions of atopic dermatitis, contact dermatitis, and psoriasis patients. CCR10+ T lymphocytes were detected in lesional but not normal skin of these patients. Flow cytometric analysis showed that CCL27 binds extracellular matrix components and dermal microvascular endothelial cells and fibroblasts and mediates adhesion and transendothelial migration of CCR10+ circulating leukocytes. CCR10 is predominantly expressed on CD4+CLA+ (cutaneous lymphocyte antigen), rather than CD8+, circulating T cells. RT-PCR, confocal microscopy, and ELISA analysis indicated that keratinocytes exposed to TNF or IL1B but not to IL4 or IFNG in vitro express increased CCL27.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CCR10 / GPR2 (C-term) antibody

  CCR10 Rabbit Polyclonal (C-Terminus) Antibody  
CCR10 / GPR2 Rabbit Aff - Purified Hu, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

CCR10 / GPR2 (2nd extracell. dom.) antibody

  CCR10 Rabbit Polyclonal (Extracellular Domain) Antibody  
CCR10 / GPR2 Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Hst, Hu, Mky, Ms, Por, Rb, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

CCR10 / GPR2 (N-term) antibody

  CCR10 Rabbit Polyclonal (N-Terminus) Antibody  
CCR10 / GPR2 Rabbit Aff - Purified Bt, Hu, Mky, Por, Rb, Rt P
50 µg / €400.00
  OriGene Technologies, Inc.

CCR10 / GPR2 (350-362) antibody

Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu F, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CCR10 - human gene knockout kit via CRISPR

CCR10 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CCR10 - human gene knockout kit via CRISPR

CCR10 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CCR10 - human gene knockout kit via CRISPR

CCR10 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CCR10 - human gene knockout kit via CRISPR

CCR10 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ccr10 - mouse gene knockout kit via CRISPR

Ccr10 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Ccr10 - mouse gene knockout kit via CRISPR

Ccr10 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ccr10 - mouse gene knockout kit via CRISPR

Ccr10 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Ccr10 - mouse gene knockout kit via CRISPR

Ccr10 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CCR10 (mGFP-tagged) - Human chemokine (C-C motif) receptor 10 (CCR10), 200 uL, >10^7 TU/mL

Lenti ORF particles, CCR10 (mGFP-tagged) - Human chemokine (C-C motif) receptor 10 (CCR10), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.

Lenti ORF particles, CCR10 (Myc-DDK tagged) - Human chemokine (C-C motif) receptor 10 (CCR10) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CCR10 (Myc-DDK tagged) - Human chemokine (C-C motif) receptor 10 (CCR10) , 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ccr10 (GFP-tagged) - Mouse chemokine (C-C motif) receptor 10 (Ccr10), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ccr10 (GFP-tagged) - Mouse chemokine (C-C motif) receptor 10 (Ccr10), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ccr10 (Myc-DDK-tagged) - Mouse chemokine (C-C motif) receptor 10 (Ccr10), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ccr10 (Myc-DDK-tagged) - Mouse chemokine (C-C motif) receptor 10 (Ccr10), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

16 Item(s)

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