CCS / SOD4 antibody

Principal name

CCS / SOD4 antibody

Alternative names for CCS / SOD4 antibody

Superoxide Dismutase Copper Chaperone, SOD-4

SwissProt ID

O14618 (Human), Q6PWT7 (Pig), Q9JK72 (Rat), Q9WU84 (Mouse)

Gene ID

9973 (CCS), 12460 (Ccs), 84485

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of CCS / SOD4 antibody

Cu-Zn superoxide dismutase-1 (SOD-1) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Copper chaperone for SOD-1 (CCS) is essential for the incorporation of copper into SOD-1, and therefore is necessary for its enzymatic activity. CCS prevents copper ions from binding to intracellular copper scavengers and provides the SOD-1 enzyme with the necessary copper cofactor. CCS escorts copper only to SOD-1 and fails to deliver copper to proteins in the mitochondria, nucleus or secretory pathway. CCS interacts with both wildtype and mutated forms of SOD-1 through CCS domains that are homologous in SOD-1. CCS exists as a homodimer that may form a heterodimer with SOD-1 during copper loading. While many tissues express CCS, the chaperone is most abundant in the kidney, liver and Purkinje cells in the neuropil of the central nervous system. The gene for CCS maps to human chromosome 11q13.

General readings

Romerius P., et al. (2010) Clin Cancer Res. 16(15):3843-50.
Seetharaman SV., et al. (2010) Biochemistry. 49(27):5714-25.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CCS / SOD4 antibody

Western blot analysis of extracts from Jurkat cells and 3T3 cells, using CCS antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CCS / SOD4 antibody

WB Suggested Anti-CCS Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CCS / SOD4 antibody

  Rabbit Polyclonal Anti-CCS Antibody  
CCS / SOD4 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CCS / SOD4 antibody

Western blot (WB) analysis of CCS antibody (Cat.-No.: AP21158PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CCS / SOD4 antibody

CCS polyclonal antibody (A01), Lot # 051206JC01. Western Blot analysis of CCS expression in human ovary cancer. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane1:CCS transfected lysate(30.14 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane1:CCS transfected lysate(30.14 KDa).
Lane2:Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane 1: CCS transfected lysate(29.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane 1: CCS transfected lysate(29.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

CCS / SOD4 Mouse IgG1 1E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Immunoprecipitation analysis of Hela cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with CCS monoclonal antibody, clone 2A1 ( Cat # MAB0679 ). Mouse IgG1 2A1 Hu E, IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Immunoblot analysis of cell lysates. Lane 1 : Hela cell lysate, lane 2 : 293T cell lysate and lane 3 : Jurkat cell lysate. Mouse IgG1 11G1 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western blot analysis of extracts from NIH-3T3/Jurkat cells, using CCS Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

CCS / SOD4 antibody

Western blot analysis of extracts from NIH-3T3/Jurkat cells, using CCS Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

CCS / SOD4 (C-term) antibody

Human MDA-MB-435S; WB Suggested Anti-CCS Antibody. . Titration: 1.0 ug/ml. . Positive Control: MDA-MB-435S Whole Cell. CCS is supported by BioGPS gene expression data to be expressed in MDA-MB435.; CCS antibody - C-terminal region (ARP61007_P050) in Human MDA-MB-435S cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CCS / SOD4 antibody

Human Fetal liver; WB Suggested Anti-CCS Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Liver; CCS antibody - middle region (ARP61008_P050) in Human Fetal liver cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CCS / SOD4 (1-274, His-tag)

CCS / SOD4 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

CCS / SOD4 (1-274, His-tag)

CCS / SOD4 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CCS / SOD4

CCS / SOD4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CCS / SOD4

CCS / SOD4 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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