CCS / SOD4 antibody
Principal name
CCS / SOD4 antibody
Alternative names for CCS / SOD4 antibody
Superoxide Dismutase Copper Chaperone, SOD-4
Ncbi ID
9606, NP_005116, NP_005116.1, NM_005125, NP_058588.1, NM_053425
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (detection) (E(detection)), EPair for Elisa (EPair)
Background of CCS / SOD4 antibody
Cu-Zn superoxide dismutase-1 (SOD-1) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Copper chaperone for SOD-1 (CCS) is essential for the incorporation of copper into SOD-1, and therefore is necessary for its enzymatic activity. CCS prevents copper ions from binding to intracellular copper scavengers and provides the SOD-1 enzyme with the necessary copper cofactor. CCS escorts copper only to SOD-1 and fails to deliver copper to proteins in the mitochondria, nucleus or secretory pathway. CCS interacts with both wildtype and mutated forms of SOD-1 through CCS domains that are homologous in SOD-1. CCS exists as a homodimer that may form a heterodimer with SOD-1 during copper loading. While many tissues express CCS, the chaperone is most abundant in the kidney, liver and Purkinje cells in the neuropil of the central nervous system. The gene for CCS maps to human chromosome 11q13.
General readings
Romerius P., et al. (2010) Clin Cancer Res. 16(15):3843-50.
Seetharaman SV., et al. (2010) Biochemistry. 49(27):5714-25.











Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA314999 | CCS / SOD4 antibody |
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Rabbit polyclonal anti-CCS antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA343094 | CCS / SOD4 antibody |
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Rabbit Polyclonal Anti-CCS Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze | WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
TA351741 | CCS / SOD4 antibody |
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Rabbit Polyclonal Anti-CCS Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
OriGene Technologies, Inc. | |||||||
AP21158PU-N | CCS / SOD4 antibody |
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Rabbit | Aff - Purified | Hu | WB |
0.1 mg /
€350.00
|
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Acris Antibodies GmbH | |||||||
C15251-1 | CCS / SOD4 antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
50 µg /
€230.00
|
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Assay Biotech | |||||||
C15251-2 | CCS / SOD4 antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
0.1 mg /
€330.00
|
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Assay Biotech |
CRISPR
Catalog No. | Species | Donor Vector | |
---|---|---|---|
KN211311 | CCS - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN211311BN | CCS - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN211311LP | CCS - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN211311RB | CCS - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302845 | Ccs - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302845BN | Ccs - mouse gene knockout kit via CRISPR |
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302845LP | Ccs - mouse gene knockout kit via CRISPR |
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302845RB | Ccs - mouse gene knockout kit via CRISPR |
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Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
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AR09653PU-L | CCS / SOD4 (1-274, His-tag) |
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Human | Purified | > 90 % by SDS - PAGE | E. coli |
0.5 mg /
€750.00
|
Acris Antibodies GmbH | |||||
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AR09653PU-N | CCS / SOD4 (1-274, His-tag) |
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Human | Purified | > 90 % by SDS - PAGE | E. coli |
0.1 mg /
€300.00
|
Acris Antibodies GmbH | |||||
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Lysates
Catalog No. | ||
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LY417482 | CCS overexpression lysate |
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0.1 mg /
€295.00
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|
OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
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RC211311L2V | Lenti ORF particles, CCS (mGFP-tagged) - Human copper chaperone for superoxide dismutase (CCS), 200 uL, >10^7 TU/mL |
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200 µl /
€989.00
|
|
OriGene Technologies, Inc. | ||
RC211311L1V | Lenti ORF particles, CCS (Myc-DDK tagged) - Human copper chaperone for superoxide dismutase (CCS) , 200 uL, >10^7 TU/mL |
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200 µl /
€886.00
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|
OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
Catalog No. | ||
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RR202926L2V | Lenti ORF particles, Ccs (GFP-tagged ORF) - Rat copper chaperone for superoxide dismutase (Ccs), 200 uL, >10^7 TU/mL |
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200 µl /
€907.00
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OriGene Technologies, Inc. | ||