CCS / SOD4 antibody

Principal name

CCS / SOD4 antibody

Alternative names for CCS / SOD4 antibody

Superoxide Dismutase Copper Chaperone, SOD-4

SwissProt ID

O14618 (Human), Q6PWT7 (Pig), Q9JK72 (Rat), Q9WU84 (Mouse)

Gene ID

9973 (CCS)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Frozen Sections (C), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Paraffin Sections (P)

Background of CCS / SOD4 antibody

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

General readings

Romerius P., et al. (2010) Clin Cancer Res. 16(15):3843-50.
Seetharaman SV., et al. (2010) Biochemistry. 49(27):5714-25.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CCS / SOD4 antibody

Western blot analysis of extracts from Jurkat cells and 3T3 cells, using CCS antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CCS / SOD4 antibody

WB Suggested Anti-CCS Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CCS / SOD4 antibody

Western blot (WB) analysis of CCS antibody (Cat.-No.: AP21158PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CCS / SOD4 antibody

CCS polyclonal antibody (A01), Lot # 051206JC01. Western Blot analysis of CCS expression in human ovary cancer. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane1:CCS transfected lysate(30.14 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane1:CCS transfected lysate(30.14 KDa).
Lane2:Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane 1: CCS transfected lysate(29.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western Blot analysis of CCS expression in transfected 293T cell line (H00009973-T01) by CCS MaxPab polyclonal antibody.

Lane 1: CCS transfected lysate(29.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

CCS / SOD4 Mouse IgG1 1E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Immunoprecipitation analysis of Hela cell lysates. Lane 1 : Input and lane 2 : Precipitates. Immunoblotting with CCS monoclonal antibody, clone 2A1 ( Cat # MAB0679 ). Mouse IgG1 2A1 Hu E, IP
0.1 ml / €390.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Immunoblot analysis of cell lysates. Lane 1 : Hela cell lysate, lane 2 : 293T cell lysate and lane 3 : Jurkat cell lysate. Mouse IgG1 11G1 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

CCS / SOD4 antibody

Western blot analysis of extracts from NIH-3T3/Jurkat cells, using CCS Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

CCS / SOD4 antibody

Western blot analysis of extracts from NIH-3T3/Jurkat cells, using CCS Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

CCS / SOD4 (C-term) antibody

Human MDA-MB-435S; WB Suggested Anti-CCS Antibody. . Titration: 1.0 ug/ml. . Positive Control: MDA-MB-435S Whole Cell. CCS is supported by BioGPS gene expression data to be expressed in MDA-MB435.; CCS antibody - C-terminal region (ARP61007_P050) in Human MDA-MB-435S cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CCS / SOD4 antibody

Human Fetal liver; WB Suggested Anti-CCS Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Liver; CCS antibody - middle region (ARP61008_P050) in Human Fetal liver cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CCS / SOD4 antibody

CCS / SOD4 Rabbit IgG Hu, Ms C, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

CCS / SOD4 antibody

CCS / SOD4 Rabbit Aff - Purified Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CCS / SOD4 antibody

CCS / SOD4 Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CCS / SOD4 antibody

CCS / SOD4 Rabbit IgG Aff - Purified Hu E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CCS / SOD4 (1-274, His-tag)

CCS / SOD4 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

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