CCT2 / TCP1 beta antibody

Principal name

CCT2 / TCP1 beta antibody

Alternative names for CCT2 / TCP1 beta antibody

99D8.1, CCT-beta, CCTB, TCP-1 beta, T-complex protein 1 subunit beta

SwissProt ID

P78371 (Human), P80314 (Mouse), P86245, Q3ZBH0 (Bovin), Q5XIM9 (Rat)

Gene ID

10576 (CCT2), 299809 (Cct2), 12461

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Sh (Sheep), Frog, Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Ye (Yeast)

Available hosts

Rat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CCT2 / TCP1 beta antibody

TCP-1 is a subunit of a cytosolic hetero-oligomer chaperone that is known to be involved in the folding of actin and tubulin. This protein is a member of the chaperonin family, which includes Escherichia coli GroEL, the mitochondrial heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein and the archaebacterial protein TF55. These chaperonins assist the folding of proteins upon ATP hydrolysis. Nine different subunits of TCP-1 containing chaperonin complexes from mammalian testis and seven different subunits of mouse F9 cells have been identified. The mouse TCP-1 subunits are between 531 and 545 residues in length. Their sequences are 25-36% identical to one another, 27-35% identical to that of TCP- 1a and 32-39% identical to that of the archaebacterial chaperonin, TF55. The genes for these subunits have been named Cctb, Cctg, Cctd, Ccte, Cctz and Ccth, which encode the CCTb, CCTg, CCTd, CCTe, CCTz, and CCTh subunits, respectively, of the Chaperonin Containing TCP-1(CCT). In bovine, CTT has also been referred to as TRic, TCP-1 ring complex. All the CCT subunits contain motifs that are also shared by all other known chaperonins of prokaryotes and eukaryotic organelles, and that probably relate to their common ATPase function. It has been suggested that each CCT subunit has a specific, independent function, as they are highly diverged from each other but conserved from mammals to yeast. The expansion in the number of types of CCT subunit, compared with other chaperonins, has allowed CCT to carry out more complex functions that are required for the folding and assembly of highly evolved eukaryotic proteins.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CCT2 / TCP1 beta antibody

Immunofluorescence analysis of 3T3-L1 cells using CCT2 Mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Mouse IgG1 5B5C4 Ascites Hu, Mky, Ms, Rt E, ICC/IF, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CCT2 / TCP1 beta (227-473) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CCT2 / TCP1 beta antibody

  Rabbit Polyclonal antibody to TCP1 beta (chaperonin containing TCP1, subunit 2 (beta))  
Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308346 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CCT2 / TCP1 beta antibody

  Rabbit Polyclonal Anti-CCT2 Antibody  
WB Suggested Anti-CCT2 Antibody; Titration: 1.0 ug/ml; Positive Control: MCF7 Whole Cell CCT2 is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CCT2 / TCP1 beta antibody

Immunohistochemical staining of normal (left) and cancerous (right) colon tissue using TCP1 beta Antibody Cat.-No. AM05385PU-N (Clone F39 P7 F11). Mouse IgG2a F39 P7 F11 Purified Frog, Hu, Ms, Rt P, WB
0.2 mg / €350.00
  Acris Antibodies GmbH

CCT2 / TCP1 beta antibody

Western blot analysis using CCT2 antibody Cat.-No AM06677SU-N against human CCT2 (AA: 87-290) recombinant protein (Expected MW is 47.9 kDa) Mouse IgG1 5B5F5 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CCT2 / TCP1 beta antibody

AM20387PU-N CCT2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Spleen Rat IgG1 PK/8/4/4i/2f Aff - Purified Bov, Can, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh P, WB
50 µg / €530.00
  Acris Antibodies GmbH

CCT2 / TCP1 beta antibody

Western blot analysis of HeLa whole cell lysate (Lane 1) and HeLa heat stressed whole cell
lysate (Lane 2) probed with Rat Anti Human CCT Beta antibody (SM2016P) followed by F(ab')2 Rabbit Anti Rat IgG:HRP (SP1021HRP). Rat IgG2b PK/8/4/4i/2F Aff - Purified Bov, Can, Chk, Hst, Hu, Mky, Ms, Por, Rb, Rt, Sh WB
0.1 mg / €640.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CCT2 - human gene knockout kit via CRISPR

CCT2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CCT2 - human gene knockout kit via CRISPR

CCT2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CCT2 - human gene knockout kit via CRISPR

CCT2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CCT2 - human gene knockout kit via CRISPR

CCT2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cct2 - mouse gene knockout kit via CRISPR

Cct2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cct2 - mouse gene knockout kit via CRISPR

Cct2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CCT2 / TCP1 beta

  Recombinant protein of human chaperonin containing TCP1, subunit 2 (beta) (CCT2)  
CCT2 / TCP1 beta Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CCT2 (mGFP-tagged) - Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CCT2 (mGFP-tagged) - Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CCT2 (mGFP-tagged)-Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CCT2 (mGFP-tagged)-Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CCT2 (Myc-DDK tagged) - Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, CCT2 (Myc-DDK tagged) - Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, CCT2 (Myc-DDK-tagged)-Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CCT2 (Myc-DDK-tagged)-Human chaperonin containing TCP1, subunit 2 (beta) (CCT2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cct2 (GFP-tagged ORF) - Rat chaperonin containing TCP1, subunit 2 (beta) (Cct2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cct2 (GFP-tagged ORF) - Rat chaperonin containing TCP1, subunit 2 (beta) (Cct2), 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.

Items 1 to 20 of 21 total

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