CD111 / Nectin 1 antibody

Principal name

CD111 / Nectin 1 antibody

Alternative names for CD111 / Nectin 1 antibody

Nectin-1, PVRL1, HVEC, PRR1, Poliovirus receptor-related protein 1, Herpes virus entry mediator C, Herpesvirus Ig-like receptor

SwissProt ID

Q15223 (Human), Q9GL76 (Pig), Q9JKF6 (Mouse)

Gene ID

5818 (PVRL1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of CD111 / Nectin 1 antibody

Nectins, which were origilly identified as virus receptors, are members of the cell-cell adhesion molecule (CAM) family. They are Ca2+-independent immunoglobulin-like CAMs. The nectin family comprises four members, nectin-1, nectin-2, nectin-3 and nectin-4, which are encoded by the PVRL1, PVRL2, PVRL3 and PVRL4 genes, respectively. In the central nervous system, these cell adhesion molecules aggregate in formations, termed puncta adherentia junctions, which are mechanical adhesive sites that connect pre- and postsyptic membranes. All nectins contain an extracellular region with three immunoglobulin-like loops (one V type and two C2 types), a single membrane-spanning region and a cytoplasmic tail. Nectins directly bind afadin, an F-actin-binding protein, through their cytoplasmic tails. Nectin-1 is expressed at cell-cell junctions in human and mouse epidermis. In mice lacking the gene encoding nectin-1 (Pvrl1-/- mice), the expression of loricrin, a differentiation marker and a major component of cornified cell envelopes in the epidermis, is downregulated and newborn pups have a shiny and slightly reddish skin. Mutations in human PVRL1 are implicated in cleft lip or palate-ectodermal dysplasia syndromes, which includes Zlotogora–Ogur syndrome and Margarita Island ectodermal dysplasia. Both of these are autosomal recessive disorders that are clinically characterized by unusual facial appearance, dental anomalies, hypotrichosis, palmoplantar hyperkeratosis and onychodysplasia, syndactyly, cleft lip or palate, and in some cases, mental retardation.

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 26 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD111 / Nectin 1 antibody

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1-2. Anti-Nectin-1 (extracellular) antibody, (1:200). 3-4. Anti-Nectin-1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CD111 / Nectin 1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-PVRL1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503521) Mouse IgG1 OTI6F8 Purified Hu ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD111 / Nectin 1 antibody

Predicted cell location: Cytoplasm. Positive control: Human stomach cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PVRL1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD111 / Nectin 1 antibody

Western blot analysis of extracts of  various cell lines, using PVRL1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD111 / Nectin 1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PVRL1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503469) Mouse IgG2a OTI1B6 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD111 / Nectin 1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (RC211214, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1. Mouse IgG1 OTI6E11 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD111 / Nectin 1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (RC211214, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1. Mouse IgG1 OTI6D12 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD111 / Nectin 1 antibody

PVRL1 polyclonal antibody (A01), Lot # 050913JC01 Western Blot analysis of PVRL1 expression in A-431 ( Cat # L015V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD111 / Nectin 1 antibody

Western Blot analysis of PVRL1 expression in transfected 293T cell line (H00005818-T01) by PVRL1 MaxPab polyclonal antibody.

Lane 1: PVRL1 transfected lysate(38.72 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD111 / Nectin 1 antibody

Immunoprecipitation of PVRL1 transfected lysate using anti-PVRL1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PVRL1 MaxPab mouse polyclonal antibody (B01) (H00005818-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

CD111 / Nectin 1 antibody

Western Blot analysis of PVRL1 expression in transfected 293T cell line (H00005818-T02) by PVRL1 MaxPab polyclonal antibody.

Lane 1: PVRL1 transfected lysate(39.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD111 / Nectin 1 (N-term) antibody

Human MCF-7; WB Suggested Anti-PVRL1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: MCF7 Whole Cell; PVRL1 antibody - N-terminal region (ARP61313_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CD111 / Nectin 1 antibody

Immunohistochemistry-Paraffin: PVRL1 Antibody [NBP1-86554] - Immunohistochemical staining of human pancreas shows strong cytoplasmic and membranous positivity in intercalated ducts. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

CD111 / Nectin 1 antibody

Antigen is Virusys # HA266-050 Purified Nectin-1 at 0.1 µg/cm. See SOP-128 for procedure.
R154 is a rabbit polyclonal antibody raised against Nectin 1. Mouse IgG1 CK6 Aff - Purified ICC/IF, WB
0.1 mg / €440.00
  Virusys Corporation

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD111 / Nectin 1 (transcript variant 1)

CD111 / Nectin 1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CD111 / Nectin 1 (transcript variant 1)

CD111 / Nectin 1 E. coli > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

CD111 / Nectin 1

CD111 / Nectin 1 Human
10 µg / €540.00
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CD111 / Nectin 1

CD111 / Nectin 1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Items 1 to 20 of 26 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn