CD112 / Nectin 2 antibody

Principal name

CD112 / Nectin 2 antibody

Alternative names for CD112 / Nectin 2 antibody

Nectin-2, PVRL2, HVEB, PRR2, Nectin-2, Poliovirus receptor-related protein 2,Herpes virus entry mediator B

SwissProt ID

P32507 (Mouse), Q92692 (Human)

Gene ID

5819 (PVRL2), 19294 (Pvrl2)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Mouse, Rabbit, Rat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of CD112 / Nectin 2 antibody

This R2.525.2 monoclonal antibody reacts with human CD112 (also known as Nectin-2 or Poliovirus Receptor Related 2), a 60-65 kDa immunoglobulin-like transmembrane cell adhesion molecule. This cell surface molecule is expressed on hematopoietic, endothelial, epithelial, and dendritic cells, as well as on tumor cell lines such as Jurkat, U937, and MCF7. CD112 is a ligand for DNAM-1 (CD226), a leukocyte adhesion molecule expressed on natural killer (NK) cells. Interaction between CD112 and DNAM-1 promotes NK cytotoxic activity, leading to tumor cell lysis. In addition to its role in tumor suppression, CD112 plays a cooperative role in cell-cell adhesion, particularly in the formation of adherens junctions between neighboring epithelial cells and fibroblasts. CD112 can form homophilic and heterophilic interactions to regulate contact inhibition of cell movement and proliferation. Finally, CD112 has been reported to be a receptor for herpesvirus entry into cells. This monoclonal antibody has been reported to block cell adhesion and herpesvirus entry.

Items 1 to 20 of 35 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD112 / Nectin 2 antibody

Sample(30 ug of whole cell lysate). A:293T. 10% SDS PAGE. TA307993 diluted at 1:500 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD112 / Nectin 2 antibody

Western blot analysis of extracts of various cell lines, using PVRL2 antibody. Rabbit IgG Purified Hu
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD112 / Nectin 2 antibody

WB Suggested Anti-PVRL2 Antibody Titration: 0.2-1 ug/ml; Positive Control: OVCAR-3 cell lysate Rabbit IgG Purified Hu, Ms, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD112 / Nectin 2 (extracell. dom.) antibody

CD112 / Nectin 2 Rat IgG2a 502-57 FITC Hu, Ms C, E, IP, WB
0.1 mg / €520.00
  Acris Antibodies GmbH

CD112 / Nectin 2 (extracell. dom.) antibody

CD112 / Nectin 2 Rat IgG2a 502-57 Purified Hu, Ms C, E, IP, WB
0.1 mg / €490.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

Flow cytometric analysis of CD112 expression on KG-1. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of AM26505AF-N to the cells. Rat IgG2a TX31 Azide Free Hu F
0.1 mg / €280.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

Flow cytometric analysis of CD112 expression on KG-1 cells. Open histogram indicate the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26505FC-N to the cells. Rat IgG2a TX31 FITC Hu F
0.1 ml / €340.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

A typical staining pattern with the B-C12 monoclonal antibody of KG-1 cell line Mouse IgG2b B-C12 Azide Free Hu F, P
0.2 mg / €270.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

A typical staining pattern with the B-C12 monoclonal antibody of KG1 cell line Mouse IgG2b B-C12 Purified Hu F, P
2ml (200T) / €250.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

CD112 / Nectin 2 Mouse IgG2b B-C12 Purified Hu P
2.5ml (50T) / €240.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

SM1777P staining of CHO nectin2 cells. Mouse IgG1 R2.525 Purified Hu C, F, IP
0.2 mg / €590.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

CD112 / Nectin 2 Mouse IgG1 R2.525 PE Hu F
0.1 mg / €210.00
  Acris Antibodies GmbH

CD112 / Nectin 2 antibody

Immunoperoxidase of purified MaxPab antibody to PVRL2 on formalin-fixed paraffin-embedded human prostate. [antibody concentration 3 ug/ml] Mouse Purified Hu E(detection), P, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD112 / Nectin 2 antibody

PVRL2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PVRL2 expression in human pancreas. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD112 / Nectin 2 antibody

CD112 / Nectin 2 Mouse IgG2a 2A6-2C1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD112 / Nectin 2 antibody

CD112 / Nectin 2 Rat IgG2a 502-57 Hu, Ms C, F, IP, WB
1 ml / €1,250.00
  Abnova Taiwan Corp.

CD112 / Nectin 2 antibody

Human OVCAR-3; WB Suggested Anti-PVRL2 Antibody Titration: 0.2-1 ug/ml. Positive Control: OVCAR-3 cell lysate; PVRL2 antibody - middle region (ARP47820_P050) in Human OVCAR-3 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CD112 / Nectin 2 antibody

Western Blot: Nectin 2 Antibody [NBP1-31486] - Western blot analysis of NBP1-31486 on 293T, with 10% SDS PAGE, diluted at 1:500. Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

CD112 / Nectin 2 antibody

CD112 / Nectin 2 Mouse IgG1 R2-525 Rt C, F, IP, P
0.1 mg / €550.00
  Novus Biologicals Inc.

CD112 / Nectin 2 antibody

CD112 / Nectin 2 Mouse IgG1 R2.525 Aff - Purified Hu F
25 Tests / €290.00
  Novus Biologicals Inc.

Items 1 to 20 of 35 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn