CD113 / Nectin 3 antibody

Principal name

CD113 / Nectin 3 antibody

Alternative names for CD113 / Nectin 3 antibody

Nectin-3, CDw113, PVRL3, PRR3, Poliovirus receptor-related protein 3

SwissProt ID

Q9JLB9 (Mouse), Q9NQS3 (Human)

Gene ID

25945 (PVRL3), 58998 (Pvrl3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F), Functional assay (FN)

Background of CD113 / Nectin 3 antibody

Nectin-3 is a 83 kDa type I transmembrane glycoprotein. Nectin, originally isolated as poliovirus receptor-related protein (PRR), is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectins are calcium-independent immunoglobulin-like cell-cell adhesion molecules consisting of four members, nectin 1-4. Nectins homophilically and heterophilically trans-interact to form a variety of cell-cell junctions, including cadherin-based adherens junctions in epithelial cells and fibroblasts in culture, synaptic junctions in neurons, and Sertoli cell-spermatid junctions in testis, in cooperation with, or independently of, cadherins. Both nectin-2 and nectin-3 are ubiquitously expressed, whereas nectin-1 is abundantly expressed in brain. Nectin-2 and -3 are expressed in cells where cadherin is not expressed, such as blood cells and spermatids. All members of the nectin family have two or three splice variants. For nectin-3, three isoforms exist: nectin-3α, -3β and -3g of which nectin-3α is the largest. Nectin-3, also known as PRR3, is a transmembrane protein that is predominantly expressed in testis and placental tissues as well in many cell lines. Nectin interacts in vivo with both long and short isoforms of afadin, an actin binding protein, at cadherin-based cell-cell adherence junctions in various tissues and cell lines. Furthermore, the ectodomains of nectin-3 and CD155 (Poliovirus Receptor) have shown strong affinity to each other. Injection of antibody 103-A1 into lumen of seminiferous tubules leads to disruption of the actin filaments in Sertoli cells at the Sertoli-maturing spermatid ectoplasmic specialization and exfoliation of maturing spermatids form the seminiferous epithelium.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253 (2010).
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010).
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642 (2009).
Yu, X., et al. Nat. Immunol. 10(1):48-57 (2009).
Fujito, T., et al. J. Cell Biol. 171(1):165-173 (2005).

Items 1 to 20 of 28 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD113 / Nectin 3 antibody

WB Suggested Anti-PVRL3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HT1080 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD113 / Nectin 3 antibody

WB Suggested Anti-PVRL3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD113 / Nectin 3 (extracell. dom.) (50-400) antibody

CD113 / Nectin 3 Rat IgG2a 103-A1 FITC Ms C, E, FN, ICC/IF, IP
0.1 mg / €490.00
  Acris Antibodies GmbH

CD113 / Nectin 3 (extracell. dom.) (50-400) antibody

CD113 / Nectin 3 Rat IgG2a 103-A1 Purified Ms C, E, FN, ICC/IF, IP
0.1 mg / €450.00
  Acris Antibodies GmbH

CD113 / Nectin 3 (C-term) antibody

Western blot analysis of CD113 / Nectin 3 Antibody (C-term) Cat.-No AP53524PU-N in MCF-7 cell line lysates (35ug/lane). This demonstrates the PVRL3 antibody detected the PVRL3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD113 / Nectin 3 antibody

CD113 / Nectin 3 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

Western Blot analysis of PVRL3 expression in transfected 293T cell line (H00025945-T01) by PVRL3 MaxPab polyclonal antibody.

Lane1:PVRL3 transfected lysate(40.26 KDa).
Lane2:Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

Immunoprecipitation of PVRL3 transfected lysate using anti-PVRL3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PVRL3 MaxPab mouse polyclonal antibody (B01) (H00025945-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

Western Blot analysis of PVRL3 expression in transfected 293T cell line (H00025945-T03) by PVRL3 MaxPab polyclonal antibody.

Lane 1: PVRL3 transfected lysate(39.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

CD113 / Nectin 3 Mouse IgG2a 1D1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

CD113 / Nectin 3 Rat IgG2a 103-A1 Ms C, E, F, IP
0.1 mg / €900.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

Western blot analysis of Pvrl3 expression in lysate from rat kidney ( Lane 1 ) and NIH/3T3 cells ( lane 2 ) . Rabbit Ms, Rt WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

CD113 / Nectin 3 antibody

Western blot analysis of extracts from A549 cells, using PVRL3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

CD113 / Nectin 3 antibody

Western blot analysis of extracts from A549 cells, using PVRL3 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

CD113 / Nectin 3 antibody

Human HT1080; WB Suggested Anti-PVRL3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HT1080 cell lysate; PVRL3 antibody - N-terminal region (ARP42446_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CD113 / Nectin 3 antibody

Human HeLa; WB Suggested Anti-PVRL3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Hela cell lysate; PVRL3 antibody - middle region (ARP42447_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CD113 / Nectin 3 antibody

Western Blot: PVRL3 Antibody [NBP1-45736] - Western blot analysis of Nectin-3
expression in lysate from rat kidney
(Lane 1) and 3T3 cells (Lane 2). Rabbit IgG Aff - Purified Ms, Rt WB
0.1 mg / €470.00
  Novus Biologicals Inc.

CD113 / Nectin 3 antibody

Western Blot: PVRL3 Antibody [NBP1-59519] - This Anti-PVRL3 antibody was used in Western Blot of HT1080     tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

CD113 / Nectin 3 antibody

CD113 / Nectin 3 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CD113 / Nectin 3 antibody

CD113 / Nectin 3 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Items 1 to 20 of 28 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn