CD114 / CSF3R antibody

Principal name

CD114 / CSF3R antibody

Alternative names for CD114 / CSF3R antibody

G-CSF-R, GCSFR, GCSF Receptor, G-CSF Receptor, Granulocyte colony-stimulating factor receptor

SwissProt ID

P40223 (Mouse), Q99062 (Human)

Gene ID

1441 (CSF3R)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of CD114 / CSF3R antibody

CSF3R(Colony-Stimulating Factor 3 Receptor, Granulocyte) also known as GCSFR or CD114((Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The CSF3R gene consists of 17 exons. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al. (1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al. (2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD114 / CSF3R antibody

  Anti-CSF3R Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSF3R antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD114 / CSF3R antibody

  Anti-CSF3R Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human lung cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSF3R antibody at dilution 1/12, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD114 / CSF3R antibody

  Rabbit Polyclonal GCSF Receptor Antibody  
Immunohistochemistry: GCSF Receptor Antibody - Most normal tissues were negative. Trophoblastic cells in placenta expressed strong cytoplasmic immunoreactivity. Myocardium, neuronal cells of cerebral cortex and Leydig cells showed moderate positivity. Among malignancies, most cancers were negative except for few adenocarcinomas of endometrium and one case of urothelial cancer that displayed moderate membranous staining in a fraction of cells.  Image and statement courtesy of the Human Protein Atlas (HPA). Rabbit IgG Purified Hu E, P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD114 / CSF3R (551-563) antibody

AP33491PU-N  (1µg/ml) staining of Peripheral Blood Lymphocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD114 / CSF3R (Center) antibody

Formalin-fixed, paraffin-embedded human colon carcinoma reacted with CD114 / CSF3R Antibody (Center) Cat.-No AP51098PU-N which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG2b S-1390 Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG1 S-1268 Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG1 S-1252 Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG2a S-1284 Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG2a S-1374 Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG2a S-425 Purified Hu E, WB
0.5 mg / €460.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG1 LMM775 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

CD114 / CSF3R antibody

CD114 / CSF3R Mouse IgG1 LMM775 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CSF3R - human gene knockout kit via CRISPR

CSF3R - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CSF3R - human gene knockout kit via CRISPR

CSF3R - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CSF3R - human gene knockout kit via CRISPR

CSF3R - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

OmniKine™ Human G-CSFR ELISA Kit

OmniKine™ Human G-CSFR ELISA Kit  
96 Tests / €440.00
  Assay Biotech

Lysates

Catalog No.    

CSF3R overexpression lysate

CSF3R overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

CSF3R overexpression lysate

CSF3R overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CSF3R (mGFP-tagged)-Human colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CSF3R (mGFP-tagged)-Human colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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