CD116 / CSF2RA antibody

Principal name

CD116 / CSF2RA antibody

Alternative names for CD116 / CSF2RA antibody

GM-CSF-R-alpha, GMR, CSF2R, CSF2RY, GMCSF Receptor alpha, GM-CSF Receptor alpha, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

SwissProt ID

P15509 (Human), Q00941 (Mouse)

Gene ID

1438 (CSF2RA)

Available reactivities

Hu (Human), Eq (Equine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD116 / CSF2RA antibody

Human IL-33, also called NF-HEV and DVS 27, is a 30 kDa proinflammatory cytokine produced by endothelial and epithelial cells. IL-33 is released during necrotic cell death but was first found in the nucleus of endothelial cells. This dual pattern of expression is reminiscent of quotalarminsquot also known as endogeneous danger signals. Other known alarmins are IL-1alpha and HMGB1. IL-33 has been identified as the ligand for ST2 (a member of the Il-1 receptor family). ST2 is stably expressed on mast cells and T(h)2 effector T cells and is functionally associated with T(h)2-mediated inflammation. Although IL-33 was initially reported to be processed by Caspase-1, recent data indicate that Caspase-3 or -7 are capable of processing IL-33 at more physiologic concentrations. IL-33 plays an immune regulatory role by inducing IL-5 and IL-13 in vitro and in vivo and activating basophils, eosinophils and mast cells. In addition to its role in proimflammation, it may also decrease inflammation through interactions with IL-1 thereby blocking its effect. Human IL-33 shares 55% amino acid sequence identity with mouse.

General readings

Hansen G., et al. (2008) Cell. 134:496-507 Suzuki T., et al. (2008) J. Exp. Med. 205:2703-2710

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD116 / CSF2RA antibody

CD116 / CSF2RA Mouse IgG1 4H1 Purified Hu C, F, IP, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD116 / CSF2RA antibody

Western blot analysis of extracts from COLO205 cells, using CSF2RA antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD116 / CSF2RA antibody

Surface staining of normal human peripheral blood cells with Anti-Human CD116 FITC (left) and PE (right).  Appropriate isotype controls were used (open histogram).  Cells in the monocyte population were used for analysis. Mouse 4H1 Purified Hu F
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD116 / CSF2RA antibody

Western blot analysis of Human lymphoma tissue using TA323988(CSF2RA Antibody) at dilution 1/200 Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD116 / CSF2RA antibody

Western blot analysis of Mouse heart tissue using TA323989(CSF2RA Antibody) at dilution 1/400 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD116 / CSF2RA antibody

Western blot analysis of Human placenta tissue and HepG2 cell using TA323990 (CSF2RA Antibody) at dilution 1/250 Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD116 / CSF2RA antibody

WB Suggested Anti-CSF2RA Antibody; Titration: 1.0 ug/ml; Positive Control: COLO205 Whole Cell Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD116 / CSF2RA antibody

CD116 / CSF2RA Mouse IgG1 4H1 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD116 / CSF2RA antibody

Western Blot analysis of CSF2RA expression in transfected 293T cell line (H00001438-T01) by CSF2RA MaxPab polyclonal antibody.

Lane 1: CSF2RA transfected lysate(44 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), F, WB
50 µl / €370.00
  Abnova Taiwan Corp.

CD116 / CSF2RA antibody

Western Blot analysis of CSF2RA expression in transfected 293T cell line (H00001438-T01) by CSF2RA MaxPab polyclonal antibody.

Lane 1: CSF2RA transfected lysate(44 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), F, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD116 / CSF2RA antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between KIT and CSF2RA. HeLa cells were stained with anti-KIT rabbit purified polyclonal 1:1200 and anti-CSF2RA mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a 2G5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD116 / CSF2RA antibody

CD116 / CSF2RA Mouse IgG mxsghk-GMCSF Hu E
0.2 mg / €390.00
  Abnova Taiwan Corp.

CD116 / CSF2RA antibody

Western blot analysis of CD116 expression in Hela (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CD116 / CSF2RA antibody

Western blot analysis of CD116 expression in Hela (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CD116 / CSF2RA antibody

Western blot analysis of CD116 expression in Hela (A); NIH3T3 (B) whole cell lysates. Rabbit Aff - Purified Hu WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CD116 / CSF2RA antibody

Flow Cytometry: CD116 Antibody (4H1) [NB100-77824] - Human peripheral blood monocytes stained with 4H1 FITC Mouse IgG1 4H1 Biotin Hu F
0.1 mg / €350.00
  Novus Biologicals Inc.

CD116 / CSF2RA antibody

CD116 / CSF2RA Mouse IgG1 4H1 Aff - Purified Hu F
0.1 mg / €320.00
  Novus Biologicals Inc.

CD116 / CSF2RA antibody

CD116 / CSF2RA Mouse IgG1 4H1 Aff - Purified Hu F
25 Tests / €290.00
  Novus Biologicals Inc.

CD116 / CSF2RA antibody

CD116 / CSF2RA Mouse IgG1 4H1 Aff - Purified Hu F
100 Tests / €330.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD116 / CSF2RA (transcript variant 2)

CD116 / CSF2RA Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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