CD11c antibody

Principal name

CD11c antibody

Alternative names for CD11c antibody

ITGAX, Integrin alpha-X, Leu M5, CD11 antigen-like family member C, Leukocyte adhesion glycoprotein p150 95 alpha chain, Leukocyte adhesion receptor p150 95

SwissProt ID

E2RTG3, P20702 (Human), Q9QXH4 (Mouse)

Gene ID

3687 (ITGAX), 16411 (Itgax)

Available reactivities

Hu (Human), Mky (Monkey), Can (Canine), Rt (Rat), Ms (Mouse), Prim (Primate)

Available hosts

Mouse, Hamster, Rat, Rabbit

Available applications

Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN), ELISA (detection) (E(detection)), Paraffin Sections (P)

Selected product citations ‐ of SM1834P

1. Pian, Y, Li, X, Zheng, Y, Wu, X, Yuan, Y, Jiang, Y. Binding of Human Fibrinogen to MRP Enhances Streptococcus suis Survival in Host Blood in a αXβ2 Integrin-dependent Manner. Sci Rep 2016, 26966, 6. PubMed PMID: 27231021.

Background of CD11c antibody

CD11c also known as Integrin alpha-X/beta-2 is a receptor for fibrinogen and recognizes the sequence G-P-R in fibrinogen. A member of the integrin alpha chain family CD11c with 1163 amino acid has seven FG-GAP repeats and a VWFA domain and is a heterodimer of an alpha and a beta subunit where alpha-X associates with beta-2. It binds with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). Recent reports suggest that CD11c helps in to capturing Ag in lymphoid tissues and acts as a DC marker, and may even act as an immunotarget for vaccine production and generation of both CD4 and CD8 T cell responses. Like CD11b, CD11c is also a cell surface adhesion receptor that is known to mediate both cell-cell and cell-matrix interactions. The functions of CD11c include phagocytosis of complement coated particles, cell migration, cytokine production by monocytes/macrophages, induction of T cell proliferation by Langerhans cells, leukocyte recruitment, capturing antigens in lymphoid tissues, and the survival of APC. It is predominantly expressed in tissue macrophages, dendritic cells, monocytes and granulocytes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD11c antibody

CD11c Hamster IgG N418 Purified Ms C, F, ICC/IF, IP
0.25 mg / €390.00
  Acris Antibodies GmbH

CD11c antibody

Flow cytometric analysis of Mouse CD11c expression on Mouse splenocytes. The staining intensity of AM26635FC-N is shown in the horizontal axis with Mouse I-A b staining on the vertical axis. Rat IgG2a 223H7 FITC Ms F
50 µg / €300.00
  Acris Antibodies GmbH

CD11c antibody

  Rabbit polyclonal antibody to CD11c (integrin, alpha X (complement component 3 receptor 4 subunit))  
Sample(30 ug whole cell lysate). A:H1299. B:Hep G2 . 7.5% SDS PAGE. TA308537 diluted at 1:1000 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse Anti-Human CD11c Purified (25 ug)  
Staining of normal human peripheral blood cells with Anti-Human CD11c FITC (left) and PE (right).  Appropriate isotype controls were used (open histogram).  Cells in the monocyte population were used for analysis. Mouse 3.9 Purified Hu F, P
25 µg / €120.00
  OriGene Technologies, Inc.

CD11c antibody

  Hamster Anti-Mouse CD11c Purified (100 ug)  
Staining of mouse splenocytes with Anti-Mouse CD11c FITC (left) and PE (right), and Anti-Human/Mouse CD45R (B220) APC.  Total viable cells were used for analysis. Hamster N418 Purified Ms F
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD11c antibody

  Anti-ITGAX Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human gastric cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ITGAX antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Anti-ITGAX Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human liver and ovarian cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded Human liver and ovarian cancer tissue using ITGAX antibody at dilution 1/15, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD11c (C-term) antibody

  Rabbit polyclonal ITGAX Antibody (C-term)  
Western blot analysis of ITGAX Antibody (C-term) (Cat. #TA324886) in MDA-MB231 cell line lysates (35ug/lane). ITGAX (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse Monoclonal ITGAX / CD11c Antibody  
Immunohistochemistry staining of Paraffin Hairy cell leukemia, bone marrow tissue by CD11c antibody (dilution: 1:20 - 1:80; visualization of staining: Cytoplasmic) Mouse IgG2a 5D11 Purified Hu P
1 ml / €860.00
  OriGene Technologies, Inc.

CD11c antibody

  Rabbit Polyclonal Anti-ITGAX Antibody (Internal)  
CD11c Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

CD11c antibody

  Rabbit Polyclonal Anti-ITGAX Antibody (Internal)  
CD11c Rabbit Aff - Purified Hu, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse Monoclonal anti-CD11c Antibody  
Human peripheral blood granulocytes were stained with purified CD11c (clone 3.9) (filled histogram) or purified mouse IgG1, ?; isotype control (open histogram), followed by anti-mouse IgG FITC. Mouse 3.9 Purified Hu F, P
0.1 mg / €248.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse monoclonal Anti-Integrin aX Clone 3.9  
CD11c Mouse IgG1 3.9 Purified Hu F, IP, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse monoclonal Anti-Integrin aX Clone KB90  
CD11c Mouse IgG1 KB90 Purified Hu F, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse monoclonal Anti-Integrin aX Clone BU15  
CD11c Mouse IgG1 BU15 Purified Can, Hu, Prim F, ICC/IF, IP, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse monoclonal Anti-CD11C Clone 118/A5  
CD11c Mouse IgG2 118/A5 Purified Hu P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD11c antibody

  Mouse monoclonal Anti-CD11C Clone CD11C-100/D2  
CD11c Mouse IgG2 CD11C-100/D2 Purified Hu IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD11c antibody

CD11c Mouse IgG1 3.9 Biotin Hu C, F
0.2 mg / €500.00
  Acris Antibodies GmbH

CD11c antibody

CD11c Mouse IgG1 CA11.6A1 Supernatant Can C, F, IP
2 ml / €450.00
  Acris Antibodies GmbH

CD11c antibody

CD11c Hamster IgG N418 Biotin Ms F
0.1 mg / €250.00
  Acris Antibodies GmbH

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