CD120b / TNFR2 antibody

Principal name

CD120b / TNFR2 antibody

Alternative names for CD120b / TNFR2 antibody

Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, TNFRSF1B, TNFBR, TNF-R2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor type II

SwissProt ID

P20333 (Human), P25119 (Mouse), Q80WY6 (Rat)

Gene ID

7133 (TNFRSF1B), 21938 (Tnfrsf1b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit, Chicken, Rat, Goat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Functional assay (FN), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of CD120b / TNFR2 antibody

The soluble form can still bind TNF-alpha with high affinity and functions as a TNF-alpha antagonist. TNF-alpha is an important signalling protein in the immune system which can activate inflammatory responses, induce apoptosis, regulate cellular proliferation, and may even promote cancer progression. TNF-alpha can bind to two structurally distinct membrane receptors, TNF-RI and TNFRII, which have both distinct and overlapping downstream signaling cascades. TNFRI is believed to be expressed on nearly all cell types, whereas TNFRII exhibits more restricted expression, being found on certain subpopulations of immune cells and several other cell types. A dominant role of TNFRII has been shown in thymocyte activation by TNF-alpha, whereas induction of cytotoxicity and other functions are mediated largely by TNF-RI. TNF-RI is equally well activated by both the 17 kDa soluble and 26 kDa membrane-bound form, whereas TNF-RII is activated only by the membrane bound form of TNF-alpha. 
TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. The TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha.

General readings

Clone 80M2 is used in this references:
1. Grell, M., et al. Lymphokine Cytokine Res. 12, 143-148 (1993)
2. Grell, M., et al. Cell 83, 793-802 (1995).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD120b / TNFR2 antibody

Human liver carcinoma stained with anti-TNF-R2 antibody Rabbit Purified Hu, Ms, Rt IP, P, WB
0.5 ml / €360.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

Human liver carcinoma stained with anti-TNF-R2 antibody Rabbit Purified Hu, Ms, Rt IP, P, WB
1 ml / €450.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

Human liver carcinoma stained with anti-TNF-R2 antibody Rabbit Purified Hu, Ms, Rt IP, P, WB
0.1 ml / €180.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

  Goat Anti-TNF-R-II / TNFR2 (mouse) Antibody  
(0.2ug/ml) staining of Rat Spinal Cord lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Rabbit polyclonal TNF Receptor II antibody  
Western blot analysis of extracts from RAW264.7 cells, HT-29 cells and LOVO cells, using TNF Receptor II antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Anti-TNFRSF1B Rabbit Polyclonal Antibody  
Predicted band size: 48 kDa . Positive control: Human colon cancer lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Anti-TNFRSF1B Rabbit Polyclonal Antibody  
Predicted band size: 48 kDa . Positive control: Human colon cancer lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/150 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Rabbit anti-TNFRSF1B Polyclonal Antibody  
Western blot analysis of 293 cell and MCF7 cell lysate using TNFRSF1B antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Anti-Human sTNF Receptor Type II Rabbit Polyclonal Antibody  
This antibody stained PC-3 and CaCo-2 cells. The primary antibody was incubated at 3.0 mg/ml overnight at 4C followed by a fluorescent labeled secondary antibody. Optimal concentrations and conditions may vary. Information is courtesy of the Cell Profiling group, SciLifeLab Stockholm. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Rabbit Polyclonal Anti-TNF-R2 Antibody  
Western blot analysis on LOVO cell lysate using TNF-R2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

  Rabbit Polyclonal Anti-TNF-R2 Antibody  
Western blot analysis on LOVO cell lysate using TNF-R2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG2a 2/220 Purified Hu C, E, FN, WB
0.1 mg / €480.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG1 80M2 Azide Free Hu F
0.1 mg / €350.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG1 80M2 FITC Hu F
50 Tests / €300.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG2a KT30 Aff - Purified Hu E
1 mg / €910.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG2a KT30 Aff - Purified Hu E
0.2 mg / €450.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG2a KT30 Aff - Purified Hu E
0.1 mg / €340.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG1 80M2 Biotin Hu, Rt E, FN, ICC/IF, IP
50 µg / €370.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG1 80M2 FITC Hu, Rt E, F, FN, ICC/IF, IP
0.1 mg / €550.00
  Acris Antibodies GmbH

CD120b / TNFR2 antibody

CD120b / TNFR2 Mouse IgG1 80M2 Purified Hu, Rt E, F, FN, ICC/IF, IP
0.1 mg / €450.00
  Acris Antibodies GmbH

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