CD124 / IL4R antibody

Principal name

CD124 / IL4R antibody

Alternative names for CD124 / IL4R antibody

Interleukin-4 receptor alpha chain, IL-4R-alpha, IL4RA, 582J2.1, IL4 Receptor alpha

SwissProt ID

P16382 (Mouse), P24394 (Human), Q63257 (Rat), Q6WG24 (Horse), Q863Z5 (Pig)

Gene ID

3566 (IL4R), 16190 (Il4ra), 25084

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Functional assay (FN), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD124 / IL4R antibody

The IL-2 receptor is a multicomponent complex consisting of three subunits, alpha, beta and gamma, each of which is required for high affinity binding of IL-2. The alpha chain functions primarily in binding IL-2, whereas the beta and gamma chains contribute to IL-2 binding and are essential to IL-2-induced activation of signaling pathways leading to T cell growth. Both IL-4R and IL-7R were initially described as single chain, high-affinity ligand-binding cytokine receptors. However, it is now well established that the IL-2Rgamma chain functions as a second subunit of the high affinity IL-4R and IL-7R receptors. Consequently, the originally described subunits of these latter receptors are now referred to as IL-4Ralpha and IL-7Ralpha, respectively, while the common subunit is referred to as gammac. Although the common gamma chain enhances ligand binding in these three cytokine receptors, it has no capacity to bind these ligands on its own. There is evidence that the gammac chain is also a subunit of IL-13R.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD124 / IL4R antibody

  Rabbit Polyclonal Anti-IL4R Antibody  
Host: Rabbit; Target Name: IL4R; Sample Tissue: HCT15 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD124 / IL4R antibody

  Rabbit Polyclonal IL4 Receptor alpha Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL4R (RC212895, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL4R. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD124 / IL4R antibody

  Rabbit Polyclonal IL4 Receptor alpha Antibody  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL4R (RC212895, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL4R. Rabbit IgG Purified Hu E, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD124 / IL4R antibody

Western blot (WB) analysis of IL-4RA antibody (Cat.-No.: AP01360PU-N) in extracts from A549 cells at 1/500 dilution. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD124 / IL4R antibody

Immunohistochemistry (IHC) analyzes of CD124 / IL4R Antibody Cat.-No AP20570PU-N in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD124 / IL4R antibody

CD124 / IL4R Mouse IgG1 25463 (49/20) Purified Hu E, F, FN, P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CD124 / IL4R (Extracell. Dom.) antibody

CD124 / IL4R Rat IgG2 16F23 Purified Ms WB
0.1 mg / €440.00
  Acris Antibodies GmbH

CD124 / IL4R pTyr497 antibody

Immunofluorescence analysis of HeLa cells, using IL-4R/CD124 (Phospho-Tyr497) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

CD124 / IL4R pTyr497 antibody

Immunofluorescence analysis of HeLa cells, using IL-4R/CD124 (Phospho-Tyr497) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CD124 / IL4R antibody

Immunofluorescence analysis of A549 cells, using IL-4R/CD124 (Ab-497) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

CD124 / IL4R antibody

Immunofluorescence analysis of A549 cells, using IL-4R/CD124 (Ab-497) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

IL4R - human gene knockout kit via CRISPR

IL4R - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

IL4R - human gene knockout kit via CRISPR

IL4R - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

IL4R - human gene knockout kit via CRISPR

IL4R - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

IL4R - human gene knockout kit via CRISPR

IL4R - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD124 / IL4R (transcript variant 1)

  Purified recombinant protein of Human interleukin 4 receptor (IL4R), transcript variant 1.  
CD124 / IL4R Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 15 µg / €399.00

Special Price: 15 µg / €239.00

  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human CD124 ELISA Kit

Human CD124 ELISA Kit  
1 kit / €179.00
  OriGene Technologies, Inc.

Human CD124 ELISA Kit

Human CD124 ELISA Kit  
1 kit / €349.00
  OriGene Technologies, Inc.

Human CD124 ELISA Kit

Human CD124 ELISA Kit  
1 kit / €549.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IL4R overexpression lysate

IL4R overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

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