CD138 / Syndecan-1 antibody

Principal name

CD138 / Syndecan-1 antibody

Alternative names for CD138 / Syndecan-1 antibody

SYND1, SDC1, SDC

SwissProt ID

P18827 (Human), P18828 (Mouse), P26260 (Rat), Q08DZ5 (Bovin)

Gene ID

6382 (SDC1), 20969 (Sdc1), 25216

Available reactivities

Hu (Human), Hst (Hamster), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C), Western blot / Immunoblot (WB), Immunoprecipitation (IP), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of CD138 / Syndecan-1 antibody

CD138 (syndecan-1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

General readings

1. Hayashida K, Johnston DR, Goldberger O, Park P.W.: Syndecan-1 expression in epithelial
cells is induced by transforming growth factor beta through a PKA-dependent pathway. J
Biol Chem. 2006 Aug 25;281(34):24365-74.
2. Choi DS, Kim JH, Ryu HS, Kim HC, Han JH, Lee JS, Min C.K.: Syndecan-1, a key
regulator of cell viability in endometrial cancer. Int J Cancer. 2007 Aug 15;121(4):741-50.
3. Manakil JF, Seymour GJ, Bartold P.M.: Effect of cytokine and antigen stimulation on
peripheral blood lymphocyte syndecan-1 expression. Oral Microbiol Immunol. 2007
Aug;22(4):272-6.
4. Muto T, Miyoshi K, Munesue S, Nakada H, Okayama M, Matsuo T, Noma T.: Differential
expression of syndecan isoforms during mouse incisor amelogenesis. J Med Invest. 2007
Aug;54(3-4):331-9.
5. Ojeh N, Hiilesvuo K, Wärri A, Salmivirta M, Henttinen T, Määttä A.: Ectopic expression of
syndecan-1 in basal epidermis affects keratinocyte proliferation and wound
re-epithelialization. J Invest Dermatol. 2008 Jan;128(1):26-34.
6. Jilani I, Wei C, Bekele BN, Zhang ZJ, Keating M, Wierda W, Ferrajoli A, Estrov Z, Kantarjian H, O'Brien SM, Giles FJ, Albitar M.: Soluble syndecan-1 (sCD138) as a prognostic factor independent of mutation status in patients with chronic lymphocytic leukemia. Int J Lab Hematol. 2008 Jan 7.
7. Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J, Yaccoby S, Shaughnessy JD Jr, Barlogie B, Sanderson RD: The syndecan-1 heparan sulfate
proteoglycan is a viable target for myeloma therapy. Blood. 2007 Sep 15;110(6):2041-8.
8. Cheriyath V, Glaser KB, Waring JF, Baz R, Hussein MA, Borden EC: G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells. J Clin Invest. 2007 Oct;117(10):3107-17.
9. Kuchen S, Robbins R, Sims GP, Sheng C, Phillips TM, Lipsky PE, Ettinger R: Essential
role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B
cell collaboration. J Immunol. 2007 Nov 1;179(9):5886-96.

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 55 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody. Rabbit IgG SP152 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 (18-218) antibody

Human Prostate (formalin-fixed, paraffin-embedded) stained with SDC1 antibody AP22709PU-N at 15 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu P
50 µg / €470.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody Rabbit IgG SP152 Purified Hu P
0.5 ml / €520.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody Rabbit IgG SP152 Purified Hu P
1 ml / €750.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody Rabbit IgG SP152 Purified Hu P
0.1 ml / €300.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody Rabbit Purified Hu P
1 ml / €450.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Human tonsil stained with anti-CD138 antibody Rabbit Purified Hu P
0.1 ml / €180.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

CD138 / Syndecan-1 Mouse DL-101 Purified Hu F, P
0.1 mg / €130.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 antibody

TA326738 (1µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 antibody

  SDC1 Rabbit Polyclonal Antibody  
Western blot analysis of extracts from HT29 cells, using SNAI1 (Phospho-Ser246) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 antibody

Immunohistochemistry staining of Paraffin Tonsil tissue by CD138 antibody (dilution: 1:25 - 1:200; visualization of staining: Membranous) Mouse IgG1 B-A38 Purified Hu P
1 ml / €690.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 antibody

Human Tonsil stained with anti-CD138 antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 antibody

ELISA: Syndecan 1 Antibody Rabbit IgG Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD138 / Syndecan-1 antibody

CD138 / Syndecan-1 Mouse IgG1 B-A38 APC Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

Flow cytometry: A typical staining pattern using U266 cell line with the B-A38 monoclonal antibody cat. no. AM03022AF-N Mouse IgG1 B-A38 Azide Free Hu C, F, P
0.2 mg / €310.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

A typical staining pattern with the B-A38 monoclonal antibody of U266 cell line Mouse IgG1 B-A38 Biotin Hu C, F, P
1ml (100T) / €270.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

CD138 / Syndecan-1 Mouse IgG1 B-A38 FITC Hu F
100 Tests / €260.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

A typical staining pattern with B-A38 monoclonal antibody of RPMI 8226 cell line Mouse IgG1 B-A38 PerCP Hu F
1ml (100T) / €300.00
  Acris Antibodies GmbH

CD138 / Syndecan-1 antibody

CD138 / Syndecan-1 Mouse IgG1 B-A38 Azide Free Hu C, F, P
0.1 mg / €250.00
  Acris Antibodies GmbH

Items 1 to 20 of 55 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn