CD140a / PDGFRA antibody

Principal name

CD140a / PDGFRA antibody

Alternative names for CD140a / PDGFRA antibody

PDGF-R-alpha, PDGF Receptor alpha, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A

SwissProt ID

P16234 (Human), P20786 (Rat), P26618 (Mouse), Q9PUF6 (Chick)

Gene ID

18595 (Pdgfra), 5156 (PDGFRA)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Fi (Fish), Hst (Hamster), Op (Opossum), Por (Porcine), Rb (Rabbit), Xen (Xenopus), Tr (Turkey), L (Lizard), Bear, Mky (Monkey)

Available hosts

Goat, Mouse, Rabbit, Rat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair), Flow Cytometry (F), Immunoprecipitation (IP)

Background of CD140a / PDGFRA antibody

PDGFRA(Platelet-derived growth factor receptor, alpha), also called PDGFR2, encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. The PDGFA gene is mapped on 4q12. The PDGFRA-FIP1L1 gene is a constitutively activated tyrosine kinase that transforms hematopoietic cells and is a therapeutic target of imatinib. The PDGFRA gene contains 23 exons spanning about 65 kb. Using the human PDGFRA promoter linked to a luciferase reporter, Joosten et al. showed that PAX1 acts as a transcriptional activator of the PDGFRA gene in differentiated human embryonal carcinoma cells. PDGFRA is responsible for mediating cellular contraction of multiple growth factors: TGFB1 and members of the PDGF family. Lei et al. noted that in the rabbit model of the disease, PDGFRA is dramatically more capable of promoting PVR than is the closely related PDGFRB. PDGFRA is a critical receptor required for human CMV infection, and thus a target for novel antiviral therapies.

General readings

Yu J. et al. (2000) J Biol Chem. 275: 19076-82.
Xie J. et al. (2001). Proc. Natl. Acad. Sci. USA 98: 9255-59.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD140a / PDGFRA antibody

Western blot analysis of extracts from HepG2 cells, using PDGFR a antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-PDGFRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804956) Mouse IgG2a OTI2E9 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PDGFRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA804990)(1:150) Mouse IgG1 OTI6E2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-PDGFRA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807645)(1:150) Mouse IgG1 OTI1C10 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

AP15723PU PDGFR alpha antibody staining of Human Ovarian Carcinoma. Rabbit Purified Hu, Rt P
0.5 ml / €360.00
  Acris Antibodies GmbH

CD140a / PDGFRA antibody

AP15723PU PDGFR alpha antibody staining of Human Ovarian Carcinoma. Rabbit Purified Hu, Rt P
1 ml / €450.00
  Acris Antibodies GmbH

CD140a / PDGFRA antibody

AP15723PU PDGFR alpha antibody staining of Human Ovarian Carcinoma. Rabbit Purified Hu, Rt P
0.1 ml / €180.00
  Acris Antibodies GmbH

CD140a / PDGFRA antibody

Staining of NIH/3T3 cell line with 0.5 ug of Rat IgG2a kappa Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse CD140a (PDGF Receptor a) Purified (filled histogram) followed by Anti-Rat IgG Biotin and Streptavidin PE .  Total viable cells were used for analysis. Rat APA5 Purified Ms F, P, WB
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

Western blot analysis of PDGFRa expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

Western blot analysis of PDGFRa phosphorylation expression in 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

Western blot analysis on 293 cell lysate using PDGFRalpha Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

Western blot analysis of PDGFR a expression in HepG2 cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

CD140a / PDGFRA Mouse IgG1 PDGFR-H7A Purified Hu IP
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

Human Ovarian Carcinoma stained with anti-PDGFR alpha antibody. Rabbit Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD140a / PDGFRA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (RC211740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA. Mouse IgG1 OTI2B12 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (RC211740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA.(1:2000) Mouse IgG2a OTI1H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (RC211740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA. Mouse IgG1 OTI4E7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (RC211740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA. Mouse IgG1 OTI1A11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (RC211740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA. Mouse IgG2b OTI3F4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD140a / PDGFRA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRA (RC211740, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRA.(1:2000) Mouse IgG2b OTI4G5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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