CD172a / SIRPA antibody

Principal name

CD172a / SIRPA antibody

Alternative names for CD172a / SIRPA antibody

SHP substrate 1, SHPS-1, Sirp-alpha-2, Sirp-alpha-3, MyD-1 antigen, p84, BIT, MFR, MYD1, PTPNS1, SHPS1, Tyrosine-protein phosphatase non-receptor type substrate 1, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antigen-like family member A

SwissProt ID

F1S887 (Pig), O46631 (Bovin), P78324 (Human), P97710 (Rat), P97797 (Mouse)

Gene ID

25528 (Sirpa), 140885 (SIRPA), 327666, 19261

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Por (Porcine), Mky (Monkey), Bov (Bovine)

Available hosts

Mouse, Rabbit, Rat

Available applications

Flow Cytometry (F), Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Functional assay (FN)

Background of CD172a / SIRPA antibody

SIRPA is a member of the sigl-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kise-coupled sigling processes. This protein can be phosphorylated by tyrosine kises. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in sigl transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. The protein encoded by this gene is a member of the sigl-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kise-coupled sigling processes. This protein can be phosphorylated by tyrosine kises. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in sigl transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple altertively spliced transcript variants have been determined for this gene.

General readings

Fujioka Y., et al. (1996) Mol Cell Biol. 16:6887-6899.Sano S., et al. (1997) FEBS Lett. 411:327-334.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD172a / SIRPA antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SIRPA mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA807751)(1:150) Mouse IgG1 OTI7B3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD172a / SIRPA antibody

Immunofluorescence of monoclonal antibody to PTPNS1 on NIH/3T3 cell. [antibody concentration 10 ug/ml] Mouse IgG2a 4C7 Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD172a / SIRPA (C-term) antibody

Western blot analysis of SIRP alpha in THP-1 whole cell lysate with SIRP alpha antibody at 1:2000 dilution. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD172a / SIRPA antibody

Western blot analysis of extracts from HepG2 cells, using Sirp a1 antibody (#TA313227).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD172a / SIRPA antibody

WB Suggested Anti-SIRPA Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD172a / SIRPA antibody

Western blot analysis on HepG2 cell lysate using SHPS1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD172a / SIRPA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRPA (RC222380, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRPA. Mouse IgG2a OTI1H1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD172a / SIRPA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRPA (RC222380, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRPA. Mouse IgG1 OTI1C6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD172a / SIRPA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRPA (RC222380, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRPA. Mouse IgG1 OTI1B5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD172a / SIRPA antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SIRPA (RC222380, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SIRPA.(1:2000) Mouse IgG1 OTI2G6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD172a / SIRPA antibody

Staining of bovine peripheral blood lymphocytes with mouse anti bovine CD172a antibody clone CC149 Cat.-No. AM01053PU-S followed by goat anti mouse IgG-FITC. Mouse IgG2b CC149 Purified Bov F
0.1 mg / €320.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

CD172a / SIRPA Mouse IgG2a 15-414 FITC Hu F
0.1 mg / €390.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

CD172a / SIRPA Mouse IgG2a 15-414 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

CD172a / SIRPA Mouse IgG2a 15-414 Purified Hu C, F
0.2 mg / €490.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

CD172a / SIRPA Mouse IgG2a 15-414 Purified Hu C, F
0.1 mg / €280.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

CD172a / SIRPA Mouse IgG2a 15-414 Purified Hu C, F
25 µg / €180.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

Peripheral Human monocytes stained with Mouse anti Human CD172a Antibody -RPE (Cat.-No AM05588RP-N). Mouse IgG2a 15-414 PE Hu F
100 Tests / €470.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

Staining of Porcine peripheral blood mononuclear cells with CD172a Antibody Cat.-No AM05885FC-N (Clone BL1H7) Mouse IgG1 BL1H7 FITC Por F
0.1 mg / €530.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

CD172a / SIRPA Mouse IgG1 BL1H7 Purified Por C, F, IP, P, WB
0.1 mg / €280.00
  Acris Antibodies GmbH

CD172a / SIRPA antibody

Immunohistochemistry (IHC) analyzes of CD172a / SIRPA antibody (Cat.-No.: AP06316PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

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