CD175 antibody

Principal name

CD175 antibody

Alternative names for CD175 antibody

Blood Group Tn Antigen

Available reactivities

Hu (Human)

Available hosts

Mouse

Available applications

Haemagglutination (H), Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Agglutination (AGG)

Background of CD175 antibody

Aberrant glycosylation is a hallmark of cancer cells. The blood group precursors T (Thomsen-Friedenreich) and Tn epitopes are shielded in healthy and benign-diseased tissues but uncovered in approx. 90% of carcinomas. T and Tn glycoproteins are specific, autoimmunogenic pancarcinoma antigens. These antigens may also be found in neoplastic blood cells Fundamental chemical and physical aspects of these glycoproteins of primary carcinomas are discussed first. Tn and T epitopes are cell and tissue adhesion molecules, essential in invasion by and metastasis of carcinoma which includes adherent and proliferative phases. Immunohistochemical studies of the extent of Tn antigen expression in primary breast carcinoma demonstrate it highly significant correlation with clinicopathological tumor stages, and hence its value as a reliable prognosticator.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD175 antibody

CD175 Mouse IgM TN218 Supernatant Hu C, ICC/IF, P
1 ml / €360.00
  Acris Antibodies GmbH

CD175 antibody

CD175 Mouse IgM TN218 Supernatant Hu C, ICC/IF, P
0.5 ml / €270.00
  Acris Antibodies GmbH

CD175 antibody

CD175 Mouse IgG1 BRIC111 Purified Hu C, E, H
0.2 mg / €430.00
  Acris Antibodies GmbH

CD175 antibody

CD175 Mouse IgG1 BRIC111 Purified Hu C, E, H
25 µg / €180.00
  Acris Antibodies GmbH

CD175 antibody

CD175 Mouse IgG1 BRIC111 Hu AGG, C
0.2 mg / €820.00
  Abnova Taiwan Corp.

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