CD192 / CCR2 antibody

Principal name

CD192 / CCR2 antibody

Alternative names for CD192 / CCR2 antibody

C-C CKR-2, CC-CKR-2, CCR-2, CMKBR2, C-C chemokine receptor type 2, Monocyte chemoattractant protein 1 receptor, MCP1-Receptor

SwissProt ID

O55193 (Rat), P41597 (Human), P51683 (Mouse)

Gene ID

729230 (CCR2), 60463 (Ccr2), 12772

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Prim (Primate)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD192 / CCR2 antibody

CCR2 is a major chemokine receptor expressed on monocytes and its activation through its ligands MCP1, MCP2, MCP3 and MCP4 (systematic mes CCL2, CCL8, CCL7 and CCL13, respectively) stimulates the migration of monocytes across the vascular wall into tissues wherein they facilitate chronic inflammation. CCR2 is a member of GPCR1 family and is up-regulated by CREB3. It is a multi-pass membrane protein found in cell membrane, and besides monocytes, it is also found on other cell types like NK cells, macrophages, immature dendritic cells, gamma delta T cells, and activated T cells (including Th17 cells). There are two altertively spliced forms of CCR2: CCR2A - the major isoform expressed by mononuclear cells and vascular smooth muscle cells; and CCR2B - expressed predomintly by monocytes and activated NK cells. CCR2 has both pro-inflammatory (mediated by APC and T cells) and anti-inflammatory (mediated by regulatory T cells) activities. Besides inflammation, it has been implicated several pathologies including HIV-1/AIDS, autoimmune disorders (psoriasis, rheumatoid arthritis, and multiple sclerosis), pulmory diseases (asthma, COPD), vascular disease and cancer (prostate cancer).

General readings

Charo, I.F., et al., (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 2752-2756.

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD192 / CCR2 antibody

Western Blot: CCR2 Antibody [TA336782] - WB analysis of CCR2 in rat lysate. Image courtesy of product review submitted by Rasha Elbaz. Rabbit Purified Hu, Rt C, F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

Western Blot: CCR2 Antibody (3G7) [TA337219] - Western blot analysis of CCR2 [3G7] in Molt4 lysate. Mouse IgG2b 3G7 Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

Western blot analysis of CCR2 expression in lysate from rat kidney (Lane 1), 3T3 cells (Lane 2) and Jurkat cells (Lane 3). Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

Immunocytochemistry/Immunofluorescence: CCR2 Antibody [TA336783] - Analysis of CCR2 in NIH/3T3 cells Rabbit IgG Purified Ms F, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

Western Blot: CCR2 Antibody (2D8) [TA337218] - Western blot analysis of CCR2 [2D8] in Molt4 lysate Mouse IgG2b 2D8 Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 (N-term, extracel. dom.) antibody

Anti-CCR2 antibody IHC of human spleen, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

CD192 / CCR2 (2nd Extracell. Dom) antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

WB Suggested Anti-CCR2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 721_B cell lysate Rabbit IgG Purified Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCR2 (RC221283, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CCR2. Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CCR2 (RC221283, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CCR2. Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD192 / CCR2 antibody

Immunohistochemistry on paraffin sections: Staining with AM26722PU-N on Human tonsil. Mouse IgG2a 7A7 Purified Hu P
0.2 mg / €420.00
  Acris Antibodies GmbH

CD192 / CCR2 antibody

CD192 / CCR2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD192 / CCR2 antibody

CCR2 monoclonal antibody (M01A), clone 4D12 Western Blot analysis of CCR2 expression in HepG2 ( Cat # L019V1 ). Mouse IgM 4D12 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

CD192 / CCR2 antibody

CD192 / CCR2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CD192 / CCR2 antibody

Western blot analysis of Ccr2 expression in lysate from rat kidney ( Lane 1 ) , NIH/3T3 cells ( Lane 2 ) and Jurkat cells ( Lane 3 ) . Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CD192 / CCR2 antibody

Human 721_B; WB Suggested Anti-CCR2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 721_B cell lysate; CCR2 antibody - middle region (ARP58409_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CD192 / CCR2 antibody

CD192 / CCR2 Rabbit IgG Purified Hu WB
0.1 mg / €310.00
  AVIVA Systems Biology

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD192 / CCR2

CD192 / CCR2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CD192 / CCR2

CD192 / CCR2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CCR2 overexpression lysate

CCR2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn