CD209b / DC-SIGNR1 antibody

Principal name

CD209b / DC-SIGNR1 antibody

Alternative names for CD209b / DC-SIGNR1 antibody

DC-SIGN-related protein 1, OtB7, CD209 antigen-like protein B

SwissProt ID

Q8CJ91 (Mouse)

Gene ID

69165 (Cd209b)

Available reactivities

Ms (Mouse)

Available hosts

Rat, Hamster

Available applications

Frozen Sections (C), Flow Cytometry (F), Functional assay (FN)

Background of CD209b / DC-SIGNR1 antibody

SIGN R1 is a specific marker for the identification of macrophage subpopulations present in the marginal zone of spleen (the so-called marginal zone macrophages (MZM)), in the lymph node medulla, and in some strains, in the peritoneal cavity. MZM of the spleen are involved in the clearance of polysaccharides.
Mouse SIGN R1 is a C type lectin, like DC SIGN which is expressed on Human dendritic cells (DCs). However, Mmouse SIGN R1 itself is not expressed on DCs. SIGN R1 exists in an aggregated form, resistant to dissociation into monomers upon boiling in SDS under reducing conditions.
SIGN R1 mediates the uptake of encapsulated organisms and may be an important mediator for the uptake of microbes in both spleen and lymph node, particularly through the recognition of microbial polysaccharides.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD209b / DC-SIGNR1 antibody

Figure 1. BM4011 CD209b/SIGN-R1 antibody staining of Mouse Spleen Frozen Section. Rat IgM ER-TR9 Purified Ms C, F
0.15 mg / €440.00
  Acris Antibodies GmbH

CD209b / DC-SIGNR1 antibody

BM4011B CD209b / DC-SIGNR1 Antibody staining of Mouse Spleen Frozen Section. Rat IgM ER-TR9 Biotin Ms C, F
0.15 mg / €530.00
  Acris Antibodies GmbH

CD209b / DC-SIGNR1 antibody

CD209b / DC-SIGNR1 Rat IgM ER-TR9 Low Endotoxin Ms C, F
0.5 mg / €680.00
  Acris Antibodies GmbH

CD209b / DC-SIGNR1 antibody

CD209b / DC-SIGNR1 Rat IgM ER-TR9 Low Endotoxin Ms C, F, FN
0.2 mg / €390.00
  Acris Antibodies GmbH

CD209b / DC-SIGNR1 antibody

CD209b / DC-SIGNR1 Rat IgM ER-TR9 Biotin Ms F
0.1 mg / €360.00
  Novus Biologicals Inc.

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