CD212 / IL12RB1 antibody

Principal name

CD212 / IL12RB1 antibody

Alternative names for CD212 / IL12RB1 antibody

Interleukin-12 receptor beta-1 chain, IL-12R-beta-1, IL-12 receptor beta, IL12 receptor beta component, IL-12RB1

SwissProt ID

P42701 (Human), Q60837 (Mouse)

Gene ID

3594 (IL12RB1), 16161

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), Frozen Sections (C), Paraffin Sections (P)

Background of CD212 / IL12RB1 antibody

The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 3' coding segment and 3' UTR compared to variant 1, resulting in a isoform (2) that contains a distinct and shorter C-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Li X., et al. (2013) . Allergy Clin. Immunol. 132 (2), 313-320Giatrakos S, et al. (2013) Cytokine 62 (2), 297-301

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD212 / IL12RB1 antibody

Sample(30 ug whole cell lysate). A:A431. 7.5% SDS PAGE. TA308386 diluted at 1:1000 Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD212 / IL12RB1 antibody

(0.3ug/ml) staining of Peripharal Blood Lymphocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD212 / IL12RB1 antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid and colon cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using IL12RB1 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD212 / IL12RB1 antibody

Predicted cell location: Cytoplasm. Positive control: Human esophagus and lung cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using IL12RB1 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD212 / IL12RB1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL12RB1 (RC216444, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL12RB1.(1:500) Mouse IgG1 OTI1A6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD212 / IL12RB1 antibody

Flow cytometric analysis of CD212 expression on parental cells (right) and transfectant cells (left). Open histgram indicates the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26476AF-N to the cells. Mouse IgG1 TOS Azide Free Hu F
0.1 mg / €360.00
  Acris Antibodies GmbH

CD212 / IL12RB1 antibody

Flow cytometric analysis of CD212 / IL-12R β1 expression on 293T cells (left) and Transfectant cells (right). Open histogram indicates the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26476RP-N to the cells. Mouse IgG1 TOS PE Hu F
50 Tests / €340.00
  Acris Antibodies GmbH

CD212 / IL12RB1 antibody

Western Blot analysis of IL12RB1 expression in transfected 293T cell line (H00003594-T01) by IL12RB1 MaxPab polyclonal antibody.

Lane 1: IL12RB1 transfected lysate(42.02 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CD212 / IL12RB1 antibody

CD212 / IL12RB1 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD212 / IL12RB1 antibody

Western Blot analysis of IL12RB1 expression in transfected 293T cell line (H00003594-T02) by IL12RB1 MaxPab polyclonal antibody.

Lane 1: IL12RB1 transfected lysate(41.91 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CD212 / IL12RB1 antibody

Immunoprecipitation of IL12RB1 transfected lysate using anti-IL12RB1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with IL12RB1 MaxPab mouse polyclonal antibody (B02) (H00003594-B02). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

CD212 / IL12RB1 antibody

Western Blot analysis of IL12RB1 expression in transfected 293T cell line (H00003594-T03) by IL12RB1 MaxPab polyclonal antibody.

Lane 1: IL12RB1 transfected lysate(42.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD212 / IL12RB1 antibody

Western Blot: IL12RB1 Antibody [NBP1-32449] - (30 ug whole cell lysate) A:A431 7.5% SDS PAGE diluted at 1:1000 Rabbit IgG Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CD212 / IL12RB1 antibody

CD212 / IL12RB1 Goat Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD212 / IL12RB1 (transcript variant 1)

CD212 / IL12RB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CD212 / IL12RB1 (1-545, His-tag)

CD212 / IL12RB1 Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €940.00
  Acris Antibodies GmbH

CD212 / IL12RB1 (1-545, His-tag)

CD212 / IL12RB1 Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €370.00
  Acris Antibodies GmbH

CD212 / IL12RB1 (24-545, His-tag)

CD212 / IL12RB1 Human Purified > 90 % by SDS - PAGE.
0.25 mg / €940.00
  Acris Antibodies GmbH

CD212 / IL12RB1 (24-545, His-tag)

CD212 / IL12RB1 Human Purified > 90 % by SDS - PAGE.
50 µg / €300.00
  Acris Antibodies GmbH

CD212 / IL12RB1

CD212 / IL12RB1 Human
10 µg / €540.00
  Abnova Taiwan Corp.

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