CD226 / DNAM1 antibody

Principal name

CD226 / DNAM1 antibody

Alternative names for CD226 / DNAM1 antibody

DNAX accessory molecule 1, DNAM-1

SwissProt ID

Q15762 (Human), Q8K4F0 (Mouse)

Gene ID

10666 (CD226), 225825 (Cd226)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit, Rat

Available applications

Functional assay (FN), Immunoprecipitation (IP), Flow Cytometry (F), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Neutralisation (NEUT)

Background of CD226 / DNAM1 antibody

CD226/DNAM-1 (DNAX accessory molecule-1) is a 65 kDa type I transmembrane glycoprotein expressed on the majority of T cells, NK cells, monocytes, and a subset of B-cells. A soluble form (50 kDa) of CD226 is present in normal serum and the supernatant of cultured activated T cells. Ligand binding to CD226 results in phosphorylation of Ser329 and Tyr322, suggesting a role in signal transduction. CD226 acts as an adhesion molecule involved in the binding of certain tumor cells to CTL and NK cells and mediates their cytotoxicity. CD226 also stimulates TNF-α and IFN-γ secretion by alloantigen-specific T cells.

General readings

Liu,J., et al. (2012) J. Immunol. 188 (11), 5511-5520Liu,R.,et al. (2012) Mol. Biol. Rep. 39 (6), 6915-6922

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD226 / DNAM1 antibody

Western blot analysis of extracts from 293 cells, treated with PMA (125ng/ml, 30mins), using CD226/DNAM-1 (Ab-329) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD226 / DNAM1 antibody

Host: Rabbit; Target Name: CD226; Sample Tissue: Fetal Liver lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Can, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD226 / DNAM1 antibody

Western blot analysis on COS7 cell lysate using CD226/DNAM-1 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD226 / DNAM1 antibody

Flow cytometric analysis of CD226 expression on lymphocytes (1), monocytes (2) and granulocytes (3). The staining intensity of AM26503AF-N is shown in the horizontal axis with CD11b staining on the vertical axis. Rat IgG2a TX25 Azide Free Hu F
0.1 mg / €280.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Flow cytometric analysis of FITC labeled CD226/DNAM-1 expression on lymphocytes (1), monocytes (2) and granulocytes (3). The staining intensity of AM26503FC-N is shown in the horizontal axis with CD11c staining on the vertical axis. Rat IgG2a TX25 FITC Hu F
50 µg / €340.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Cell Source: Spleen
Percentage of cells stained above control: 26.4% Rat IgM 15F.10E5 FITC Ms F
0.1 mg / €330.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

CD226 / DNAM1 Rat IgM 15F.10E5 Purified Ms F
0.25 mg / €400.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Western blot (WB) analysis of CD226 antibody (Cat.-No.: AP01352PU-N) in extracts from 293 cells treated with PMA 125ng/ml 30' Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD226:AZIDE FREE (SM2023A). Mouse IgG1 DX11 Azide Free Hu F, FN, IP
1 mg / €790.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

CD226 / DNAM1 Mouse IgG1 DX11 Biotin Hu F, IP
0.1 mg / €430.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD226:FITC (SM2023F). Mouse IgG1 DX11 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD226 : LOW ENDOTOXIN (SM2023LE). Mouse IgG1 DX11 Low Endotoxin Hu F, FN, IP
0.5 mg / €540.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

CD226 / DNAM1 Mouse IgG1 DX11 Aff - Purified Hu F, IP
0.2 mg / €490.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD226 (SM2023PS). Mouse IgG1 DX11 Aff - Purified Hu F, IP
0.1 mg / €270.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD226 (SM2023PS). Mouse IgG1 DX11 Aff - Purified Hu F, IP
25 µg / €180.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD226 -RPE Mouse IgG1 DX11 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD226 -RPE Mouse IgG1 DX11 PE Hu F
25 Tests / €220.00
  Acris Antibodies GmbH

CD226 / DNAM1 antibody

CD226 / DNAM1 Mouse IgG2a 4G8 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD226 / DNAM1 antibody

CD226 / DNAM1 Mouse IgG1 DX11 Hu F, IP
0.1 mg / €730.00
  Abnova Taiwan Corp.

CD226 / DNAM1 pSer329 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using CD226/DNAM-1 (Phospho-Ser329) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

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