CD23 antibody

Principal name

CD23 antibody

Alternative names for CD23 antibody

Fc-epsilon-RII, FCER2, CD23A, FCE2, IGEBF, Low affinity immunoglobulin epsilon Fc receptor, Lymphocyte IgE receptor, Immunoglobulin E-binding factor

SwissProt ID

P06734 (Human), P20693 (Mouse)

Gene ID

14128 (Fcer2a), 2208 (FCER2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Rat

Available applications

Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Functional assay (FN), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Neutralisation (NEUT)

Background of CD23 antibody

CD23, also known as Fc epsilon RII, or FcεRII, is the "low affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites and is important in regulation of IgE levels. Human rIL-4 is able to induce the expression of low-affinity receptors for IgE (Fc epsilon RL/CD23) on resting B lymphocytes, as determined by the binding of either the anti Fc epsilon RL/CD23-specific mAb 25 or IgE. Stimulation of B cells with insolubilized anti-IgM antibody increases the number of cells expressing Fc epsilon RL/CD23 upon culturing with IL-4 and enhances the level of Fc epsilon RL/CD23 expression on these cells. Fc epsilon RL/CD23 induction is specific for IL-4 since IL-1 alpha, IL-2, IFN-gamma, B cell-derived B cell growth factor (BCGF), and a low-molecular-weight BCGF were ineffective. IFN-gamma strongly inhibited the induction of Fc epsilon RL/CD23 by IL-4. CD23 is a 45 kDa transmembrane glycoprotein associated with MHC Class II antigen, which belongs to the C-type lectin family. Expression of CD23 by B lymphocytes is up-regulated following mitogen or antigen activation. Soluble forms of CD23 are generated by proteolytic cleavage of the membrane molecule. (Defrance T. et al., J Exp Med, 1987,165, 1459 ; Bonnefoy J-Y., et al., 1996, Eur.Respir.J., 9, 635-665).

General readings

Yamamoto, H. et al., J Immunol.,1998; 161(2): 971-7.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD23 antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (UM800031; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG2a UMAB101 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD23 antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (UM800031; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG2a UMAB101 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
0.1 ml / €320.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
0.2 ml / €440.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
0.5 ml / €550.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
1 ml / €870.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (48-248) antibody

AM11101PU CD23 antibody staining of Human tonsil. Rabbit SP23 Supernatant Hu F, P, WB
0.5 ml / €540.00
  Acris Antibodies GmbH

CD23 (48-248) antibody

AM11101PU CD23 antibody staining of Human tonsil. Rabbit SP23 Supernatant Hu F, P, WB
1 ml / €780.00
  Acris Antibodies GmbH

CD23 (48-248) antibody

AM11101PU CD23 antibody staining of Human tonsil. Rabbit SP23 Supernatant Hu F, P, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

CD23 antibody

Human tonsil stained with anti-CD23 Antibody Cat.-No AM32444PU (Clone SP163). Rabbit IgG SP163 Purified Hu F, P, WB
0.5 ml / €540.00
  Acris Antibodies GmbH

CD23 antibody

Human tonsil stained with anti-CD23 Antibody Cat.-No AM32444PU (Clone SP163). Rabbit IgG SP163 Purified Hu F, P, WB
1 ml / €780.00
  Acris Antibodies GmbH

CD23 antibody

Human tonsil stained with anti-CD23 Antibody Cat.-No AM32444PU (Clone SP163). Rabbit IgG SP163 Purified Hu F, P, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

CD23 antibody

Human tonsil stained with anti-CD23 antibody Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

CD23 antibody

Human tonsil stained with anti-CD23 antibody Rabbit Purified Hu P
1 ml / €440.00
  Acris Antibodies GmbH

CD23 antibody

Human tonsil stained with anti-CD23 antibody Rabbit Purified Hu P
0.1 ml / €180.00
  Acris Antibodies GmbH

CD23 antibody

Staining of normal human peripheral blood cells with 0.5 ug of  Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.25ug of Anti-Human CD23 Purified (filled histogram) followed by Anti-Mouse IgG FITC .  Cells in the lymphocyte gate were used for analysis. Mouse EBVCS2 Purified Hu F
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD23 antibody

Western blot analysis of extracts of 293T cell lines, using FCER2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD23 antibody

Immunohistochemistry staining of Paraffin Tonsil tissue by CD23 antibody (dilution: 1:10 - 1:50; visualization of staining: Membranous) Mouse IgG1 1B12 Purified Hu P
1 ml / €690.00
  OriGene Technologies, Inc.

CD23 antibody

Immunohistochemistry staining of Paraffin Tonsil, lymph node, chronic lymphocytic leukemia, small lymphocytic lymphoma tissue by CD23 antibody (dilution: 1:100 - 1:500; visualization of staining: Membranous) Mouse IgG2a MRQ-57 Purified Hu P
1 ml / €530.00
  OriGene Technologies, Inc.

CD23 antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801531) Mouse IgG1 OTI2B6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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