CD23 antibody

Principal name

CD23 antibody

Alternative names for CD23 antibody

Fc-epsilon-RII, FCER2, CD23A, FCE2, IGEBF, Low affinity immunoglobulin epsilon Fc receptor, Lymphocyte IgE receptor, Immunoglobulin E-binding factor

SwissProt ID

P06734 (Human), P20693 (Mouse)

Gene ID

14128 (Fcer2a), 2208 (FCER2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Rat

Available applications

Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Functional assay (FN), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD23 antibody

CD23, also known as Fc epsilon RII, or FcεRII, is the "low affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites and is important in regulation of IgE levels. Human rIL-4 is able to induce the expression of low-affinity receptors for IgE (Fc epsilon RL/CD23) on resting B lymphocytes, as determined by the binding of either the anti Fc epsilon RL/CD23-specific mAb 25 or IgE. Stimulation of B cells with insolubilized anti-IgM antibody increases the number of cells expressing Fc epsilon RL/CD23 upon culturing with IL-4 and enhances the level of Fc epsilon RL/CD23 expression on these cells. Fc epsilon RL/CD23 induction is specific for IL-4 since IL-1 alpha, IL-2, IFN-gamma, B cell-derived B cell growth factor (BCGF), and a low-molecular-weight BCGF were ineffective. IFN-gamma strongly inhibited the induction of Fc epsilon RL/CD23 by IL-4. CD23 is a 45 kDa transmembrane glycoprotein associated with MHC Class II antigen, which belongs to the C-type lectin family. Expression of CD23 by B lymphocytes is up-regulated following mitogen or antigen activation. Soluble forms of CD23 are generated by proteolytic cleavage of the membrane molecule. (Defrance T. et al., J Exp Med, 1987,165, 1459 ; Bonnefoy J-Y., et al., 1996, Eur.Respir.J., 9, 635-665).

General readings

Yamamoto, H. et al., J Immunol.,1998; 161(2): 971-7.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD23 antibody

  FCER2 mouse monoclonal antibody,clone UMAB101  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (UM800031; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG2a UMAB101 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD23 antibody

  FCER2 mouse monoclonal antibody,clone UMAB101  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (UM800031; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG2a UMAB101 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
0.1 ml / €320.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
0.2 ml / €440.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
0.5 ml / €550.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 (C-term) antibody

Formalin-fixed and paraffin-embedded human tonsil tissue (4 μm) stained with anti-CD23 antibody (DB 135) shows strong and distinct staining of the follicular dendritic cells in the germinal centres, and a strong and distinct membranous staining of the activated B-cells in the mantle zone of germinal center of the human tonsil. Rabbit IgG E28-S Aff - Purified Hu P
1 ml / €870.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 antibody

  Mouse Anti-Human CD23 Purified (100 ug)  
Staining of normal human peripheral blood cells with 0.5 ug of  Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.25ug of Anti-Human CD23 Purified (filled histogram) followed by Anti-Mouse IgG FITC .  Cells in the lymphocyte gate were used for analysis. Mouse EBVCS2 Purified Hu F
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD23 antibody

  FCER2 Rabbit Polyclonal Antibody  
Western blot analysis of extracts of 293T cell lines, using FCER2 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD23 antibody

  Mouse Monoclonal CD23 Antibody  
Immunohistochemistry staining of Paraffin Tonsil tissue by CD23 antibody (dilution: 1:10 - 1:50; visualization of staining: Membranous) Mouse IgG1 1B12 Purified Hu P
1 ml / €1,000.00
  OriGene Technologies, Inc.

CD23 antibody

  Mouse Monoclonal CD23 Antibody  
Immunohistochemistry staining of Paraffin Tonsil, lymph node, chronic lymphocytic leukemia, small lymphocytic lymphoma tissue by CD23 antibody (dilution: 1:100 - 1:500; visualization of staining: Membranous) Mouse IgG2a MRQ-57 Purified Hu P
1 ml / €680.00
  OriGene Technologies, Inc.

CD23 antibody

  Rat Monoclonal anti-CD23 Antibody  
CD57BL/6 mouse splenocytes were stained with purified CD23 (clone B3B4) (filled histogram), or purified rat IgG2a, kappa; (open histogram), followed by anti-rat IgG FITC. Rat B3B4 Purified Ms F, ICC/IF, IP, P
0.5 mg / €325.00
  OriGene Technologies, Inc.

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI2B6 (formerly 2B6)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801531) Mouse IgG1 OTI2B6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI6C2 (formerly 6C2)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801554) Mouse IgG2a OTI6C2 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI7C9 (formerly 7C9)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCER2 (RC204335, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCER2. Mouse IgG2a OTI7C9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI3A2 (formerly 3A2)  
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-FCER2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801571) Mouse IgG2a OTI3A2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI2H2 (formerly 2H2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCER2 (RC204335, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCER2. Mouse IgG2a OTI2H2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI1E5 (formerly 1E5)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCER2 (RC204335, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCER2. Mouse IgG2b OTI1E5 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

  FCER2 mouse monoclonal antibody, clone OTI9B6 (formerly 9B6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FCER2 (RC204335, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FCER2. Mouse IgG2b OTI9B6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD23 antibody

CD23 Rabbit IgG S25-H FITC Hu F
100 Tests / €560.00
  DB Biotech, spol. s r.o.

Sample sizes available

CD23 antibody

CD23 Mouse IgG1 Bu38 Purified Hu F
0.1 mg / €390.00
  Acris Antibodies GmbH

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