CD233 / SLC4A1 antibody

Principal name

CD233 / SLC4A1 antibody

Alternative names for CD233 / SLC4A1 antibody

AE1, Band 3 anion transport protein, Anion Exchanger 1, EPB3, Anion exchange protein 1, Solute carrier family 4 member 1

SwissProt ID

P02730 (Human), P04919 (Mouse), P15575 (Chick), P23562 (Rat)

Gene ID

6521 (SLC4A1), 20533 (Slc4a1), 24779

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Ms (Mouse), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C)

Background of CD233 / SLC4A1 antibody

The CD233 gene is located on chromosome 17q21-q22 and is part of the anion exchanger (AE) family. CD233 is expressed in the erythrocyte plasma membrane where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. CD233 associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of CD233. CD233 is predominantly dimeric but forms tetramers in the presence of ankyrin. Many CD233 mutations are known in man and these mutations can lead to two types of disease; destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other CD233 mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. Southeast Asian ovalocytosis (SAO, Melanesian ovalocytosis) results from the heterozygous presence of a deletion in the CD233 protein and is common in areas where Plasmodium falciparum malaria is endemic. One CD233 null human is known also with very severe anemia and nephrocalcinosis [PROW].

General readings

Kittanakom,S., et al., (2004) J. Biol. Chem. 279 (39), 40960-40971

20 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD233 / SLC4A1 (N-term) antibody

  Band 3 / AE1 Rabbit Polyclonal (N-Terminus) Antibody  
CD233 / SLC4A1 Rabbit IgG Aff - Purified Hu E, P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

CD233 / SLC4A1 antibody

  Rabbit Polyclonal Anti-ACAT2 Antibody  
WB Suggested Anti-ACAT2 Antibody Titration: 1.0ug/ml; Positive Control: K562 cell lysateSLC4A1 is supported by BioGPS gene expression data to be expressed in K562 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD233 / SLC4A1 antibody

  Rabbit Polyclonal Anti-SLC4A1 Antibody  
WB Suggested Anti-SLC4A1 Antibody Titration: 0.1 ug/ml; Positive Control: Human Liver Rabbit IgG Purified Eq, Hu, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD233 / SLC4A1 antibody

  Rabbit Polyclonal Anti-SLC4A1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (SLC4A1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

SLC4A1 - human gene knockout kit via CRISPR

SLC4A1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

SLC4A1 - human gene knockout kit via CRISPR

SLC4A1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

SLC4A1 - human gene knockout kit via CRISPR

SLC4A1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

SLC4A1 - human gene knockout kit via CRISPR

SLC4A1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc4a1 - mouse gene knockout kit via CRISPR

Slc4a1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Slc4a1 - mouse gene knockout kit via CRISPR

Slc4a1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc4a1 - mouse gene knockout kit via CRISPR

Slc4a1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Slc4a1 - mouse gene knockout kit via CRISPR

Slc4a1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD233 / SLC4A1

  Recombinant protein of human solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1)  
CD233 / SLC4A1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

SLC4A1 overexpression lysate

SLC4A1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SLC4A1 (mGFP-tagged) - Human solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1), 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC4A1 (mGFP-tagged) - Human solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, SLC4A1 (Myc-DDK tagged) - Human solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, SLC4A1 (Myc-DDK tagged) - Human solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Slc4a1 (GFP-tagged) - Mouse solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc4a1 (GFP-tagged) - Mouse solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL  
200 µl / €1,690.00
  OriGene Technologies, Inc.

Lenti ORF particles, Slc4a1 (Myc-DDK-tagged) - Mouse solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc4a1 (Myc-DDK-tagged) - Mouse solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL  
200 µl / €1,520.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Slc4a1 (GFP-tagged ORF) - Rat solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc4a1 (GFP-tagged ORF) - Rat solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL  
200 µl / €1,680.00
  OriGene Technologies, Inc.

Lenti ORF particles, Slc4a1 (Myc-DDK-tagged ORF) - Rat solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Slc4a1 (Myc-DDK-tagged ORF) - Rat solute carrier family 4 (anion exchanger), member 1 (Slc4a1), 200 uL, >10^7 TU/mL  
200 µl / €1,515.00
  OriGene Technologies, Inc.

20 Item(s)

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