CD234 / DARC antibody

Principal name

CD234 / DARC antibody

Alternative names for CD234 / DARC antibody

Duffy antigen/chemokine receptor, Fy glycoprotein, GpFy, Glycoprotein D, FY, GPD, Plasmodium vivax receptor

SwissProt ID

Q16570 (Human), Q9GLX0 (Bovin), Q9QUI6 (Mouse)

Gene ID

2532 (DARC)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of CD234 / DARC antibody

DARC, also known as the Duffy antigen/chemokine receptor, is a seven-transmembrane protein homologous to the classical chemokine G-protein coupled receptors (GPCRs) with the exception of the motif required for G protein coupling. DARC can bind with high affinity several chemokines without transducing any signal, suggesting it may modulate the signals normally induced by these chemokines. Recently, DARC was found to interact with KAI1, a four transmembrane protein recently identified as a tumor metastasis suppressor protein. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least three isoforms of DARC are known to exist.

General readings

Bruhl H, Vielhauer V, Weiss M, Mack M, Schlondorff D, Segerer S. Expression of DARC, CXCR3 and CCR5 in giant cell arteritis. Rheumatology (Oxford). 2005 Mar;44(3):309-13. Epub 2004 Nov 30. PMID: 15572394

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD234 / DARC (N-term) antibody

TA303060 (0.1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu F, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD234 / DARC (C-term) antibody

Western blot analysis of DARC in mouse brain tissue lysate with DARC antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD234 / DARC (N-term) antibody

Western blot analysis of DARC in PC-3 cell lysate with DARC antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD234 / DARC antibody

Immunofluorescence analysis of A549 cells, using CD234 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD234 / DARC (C-term) antibody

Colon, vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD234 / DARC (6-24) antibody

Figure 1. Immunohistochemical analysis of Formalin-Fixed Paraffin-Embedded Human Lung, vessel tissue using AP08783PU-N at 2.5 µg/ml. Goat IgG Aff - Purified Hu, Mky, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD234 / DARC Control Peptide

CD234 / DARC
50 µg / €160.00
  Acris Antibodies GmbH

CD234 / DARC Control Peptide

CD234 / DARC
50 µg / €160.00
  Acris Antibodies GmbH

CD234 / DARC (1-50) antibody

Human Thymus, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, ICC/IF, P
50 µl / €470.00
  Acris Antibodies GmbH

CD234 / DARC antibody

Western Blot analysis of DARC expression in transfected 293T cell line (H00002532-T01) by DARC MaxPab polyclonal antibody.

Lane 1: FY transfected lysate(37.07 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

Western Blot analysis of DARC expression in transfected 293T cell line (H00002532-T01) by DARC MaxPab polyclonal antibody.

Lane 1: FY transfected lysate(37.07 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

Western Blot analysis of DARC expression in transfected 293T cell line (H00002532-T02) by DARC MaxPab polyclonal antibody.

Lane 1: DARC transfected lysate(35.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Serum Hu, Ms E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

Western Blot analysis of DARC expression in transfected 293T cell line (H00002532-T02) by DARC MaxPab polyclonal antibody.

Lane 1: DARC transfected lysate(35.60 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

DARC polyclonal antibody ( Cat # PAB6873 ) ( 3 µg/ml ) staining of paraffin embedded human kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Hu E, F, P, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

Immunohistochemistry of DARC in mouse brain tissue with DARC polyclonal antibody ( Cat # PAB13254 ) at 2.5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

Immunohistochemistry of DARC in human brain tissue with DARC polyclonal antibody ( Cat # PAB13255 ) at 5 µg/ml. Rabbit Hu P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD234 / DARC antibody

Immunofluorescence analysis of A549 cells, using CD234 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
50 µg / €205.00
  Assay Biotech

CD234 / DARC antibody

Immunofluorescence analysis of A549 cells, using CD234 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

CD234 / DARC antibody

Immunohistochemistry:Duffy / FY / DARC Antibody [NB100-2421] (3ug/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining. Goat IgG Aff - Purified Hu E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CD234 / DARC antibody

CD234 / DARC Mouse IgG2a Hu F, P
50 µl / €410.00
  Novus Biologicals Inc.

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