CD234 / DARC antibody

Principal name

CD234 / DARC antibody

Alternative names for CD234 / DARC antibody

Duffy antigen/chemokine receptor, Fy glycoprotein, GpFy, Glycoprotein D, FY, GPD, Plasmodium vivax receptor

SwissProt ID

Q16570 (Human), Q9GLX0 (Bovin), Q9QUI6 (Mouse)

Gene ID

2532 (DARC), 13349 (Darc)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Prim (Primate)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD234 / DARC antibody

DARC, also known as the Duffy antigen/chemokine receptor, is a seven-transmembrane protein homologous to the classical chemokine G-protein coupled receptors (GPCRs) with the exception of the motif required for G protein coupling. DARC can bind with high affinity several chemokines without transducing any signal, suggesting it may modulate the signals normally induced by these chemokines. Recently, DARC was found to interact with KAI1, a four transmembrane protein recently identified as a tumor metastasis suppressor protein. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least three isoforms of DARC are known to exist.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD234 / DARC (N-term) antibody

  Goat Polyclonal Antibody against DARC  
TA303060 (0.1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu F, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD234 / DARC (C-term) antibody

  Rabbit Polyclonal DARC Antibody  
Western blot analysis of DARC in mouse brain tissue lysate with DARC antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD234 / DARC (N-term) antibody

  Rabbit Polyclonal DARC Antibody  
Western blot analysis of DARC in PC-3 cell lysate with DARC antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD234 / DARC antibody

  Rabbit polyclonal anti-CD234 antibody  
Immunofluorescence analysis of A549 cells, using CD234 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD234 / DARC (C-term) antibody

Colon, vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD234 / DARC (6-24) antibody

Figure 1. Immunohistochemical analysis of Formalin-Fixed Paraffin-Embedded Human Lung, vessel tissue using AP08783PU-N at 2.5 µg/ml. Goat IgG Aff - Purified Hu, Mky E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD234 / DARC (1-50) antibody

Human Thymus, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, ICC/IF, P
50 µl / €470.00
  Acris Antibodies GmbH

CD234 / DARC antibody

Immunofluorescence analysis of A549 cells, using CD234 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
50 µg / €230.00
  Assay Biotech

CD234 / DARC antibody

Immunofluorescence analysis of A549 cells, using CD234 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

DARC - human gene knockout kit via CRISPR

DARC - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

DARC - human gene knockout kit via CRISPR

DARC - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

DARC - human gene knockout kit via CRISPR

DARC - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Darc - mouse gene knockout kit via CRISPR

Darc - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Darc - mouse gene knockout kit via CRISPR

Darc - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Darc - mouse gene knockout kit via CRISPR

Darc - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD234 / DARC (transcript variant 2)

  Recombinant protein of human Duffy blood group, chemokine receptor (DARC), transcript variant 2  
CD234 / DARC Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACKR1 (mGFP-tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACKR1 (mGFP-tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €910.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACKR1 (mGFP-tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACKR1 (mGFP-tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACKR1 (Myc-DDK tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ACKR1 (Myc-DDK tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €810.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACKR1 (Myc-DDK tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ACKR1 (Myc-DDK tagged) - Human Duffy blood group, chemokine receptor (DARC), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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