CD243 / MDR1 antibody

Principal name

CD243 / MDR1 antibody

Alternative names for CD243 / MDR1 antibody

Multidrug resistance protein 1, P-glycoprotein 1, ABCB1, PGY1, ATP-binding cassette sub-family B member 1

SwissProt ID

P06795 (Mouse), P08183 (Human), P21448 (Crigr), P43245 (Rat)

Gene ID

5243 (ABCB1), 18669 (Abcb1b)

Available reactivities

Hu (Human), Can (Canine), Mky (Monkey), Ms (Mouse), Rt (Rat), Prim (Primate), Hst (Hamster)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F)

Background of CD243 / MDR1 antibody

Cells selected for resistance to a single cytotoxic drug may become crossresistant to a broad range of drugs with different structures and cellular targets. This phenomenon is called multiple drug resistance (MDR). The MDR proteins (Mdrs) are members of a highly conserved superfamily of ATPbinding cassette transport proteins. Mdr functions as an energy-dependent efflux pump for structurally diverse agents ranging from ions to peptides. It is implicated in the development of the multiple drug resistance observed in human cancer cells following prolonged chemotherapy. The classic form of MDR is associated with an increase in the Mdr protein, but not all cases of MDR can be attributed to a rise in Mdr levels. Mdr-1 is an apical transmembrane protein that is an integral part of the blood-brain barrier and functions as a drug-transport pump transporting a variety of drugs from the brain back into the blood. In the human population, there are 15 polymorphisms in the Mdr-1 gene.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI2F7 (formerly 2F7)  
Western blot analysis of extracts (15ug) from 4 different cell lines by using anti-ABCB1 monoclonal antibody (Lane 1: 293T; Lane 2: UO_31; Lane 3: HCT_115; Lane 4: Hela). Mouse IgG1 OTI2F7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI2C7 (formerly 2C7)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801006) Mouse IgG1 OTI2C7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI6H2 (formerly 6H2)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801007) Mouse IgG2a OTI6H2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI2G6 (formerly 2G6)  
Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801008) Mouse IgG1 OTI2G6 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 (P Glycoprotein) mouse monoclonal antibody, clone OTI5B3 (formerly 5B3)  
Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801055) Mouse IgG2a OTI5B3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI8A9 (formerly 8A9)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806679) Mouse IgG2b OTI8A9 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI11D2 (formerly 11D2)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806689) Mouse IgG2a OTI11D2 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI1A7 (formerly 1A7)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806702) Mouse IgG2a OTI1A7 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI10H3 (formerly 10H3)  
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806730) Mouse IgG2b OTI10H3 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 (262-277) antibody

  Rabbit polyclonal anti-ABCB1 antibody  
Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. Personal Communication, Anna Calcagno, CCR-NCI, Bethesda, MD. Rabbit IgG Aff - Purified Can, Hu, Mky, Ms, Rt E, WB
0.1 mg / €356.00
  OriGene Technologies, Inc.

CD243 / MDR1 antibody

  Rabbit Polyclonal Anti-ABCB1 Antibody (Cytoplasmic Domain)  
Anti-ABCB1 / MDR1 antibody IHC of human kidney, proximal convoluted tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky
50 µg / €400.00
  OriGene Technologies, Inc.

CD243 / MDR1 (Cytopl. Dom.) antibody

  Rabbit Polyclonal Anti-ABCB1 Antibody (Cytoplasmic Domain)  
Anti-ABCB1 / MDR1 antibody IHC of human adrenal, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

CD243 / MDR1 antibody

  Rabbit Polyclonal Anti-ABCB1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (ABCB1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD243 / MDR1 antibody

  Mouse Monoclonal anti-CD243 (ABCB1, P-glycoprotein 1) Antibody  
Immunohistochemical staining of CD243 (ABCB1, P-glycoprotein 1), on formalin fixed paraffin embedded normal human liver tissue. Mouse IgG2a C494 Purified Hu, Prim ICC/IF, IP, P
1 ml / €679.00
  OriGene Technologies, Inc.

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI2G4 (formerly 2G4)  
SF9 cells lysate (5 ug, left lane) and SF9 cells lysate expressing human recombinant protein fragment (5 ug, right lane) corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) were separated by SDS-PAGE and immunoblotted with anti-ABCB1 Mouse IgG1 OTI2G4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI2G7 (formerly 2G7)  
SF9 cells lysate (5 ug, left lane) and SF9 cells lysate expressing human recombinant protein fragment (5 ug, right lane) corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) were separated by SDS-PAGE and immunoblotted with anti-ABCB1 Mouse IgG1 OTI2G7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI3H7 (formerly 3H7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or fragment (347-710 AA) of ABCB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCB1. Mouse IgG1 OTI3H7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  Purified ABCB1 mouse monoclonal antibody, clone OTI3C8 (formerly 3C8)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ABCB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA801003) Mouse IgG1 OTI3C8 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI2H10 (formerly 2H10)  
Mock SF9 cells lysate (5 ug, left lane) and SF9 cells lysate expressing human recombinant protein fragment (5 ug, right lane) corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) were separated by SDS-PAGE and immunoblotted with anti-ABCB1 Mouse IgG1 OTI2H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD243 / MDR1 antibody

  ABCB1 mouse monoclonal antibody, clone OTI5F1 (formerly 5F1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or fragment (995-1280 AA) of ABCB1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCB1. Mouse IgG2b OTI5F1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Items 1 to 20 of 47 total

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Page:
  1. 1
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