CD263 / TRAILR3 antibody

Principal name

CD263 / TRAILR3 antibody

Alternative names for CD263 / TRAILR3 antibody

Decoy receptor 1, TNFRSF10C, DCR1, LIT, TRID, TRAIL receptor 3, TRAIL-R3, Tumor necrosis factor receptor superfamily member 10C, Decoy TRAIL receptor without death domain, TNF-related apoptosis-inducing ligand receptor 3, Trail receptor without an intracellular domain, Lymphocyte inhibitor of TRAIL, Antagonist decoy receptor for TRAIL/Apo-2L

SwissProt ID

O14798 (Human)

Gene ID

8794 (TNFRSF10C), 79201 (Tnfrsf23), 23405 (DICER1)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Functional assay (FN), Frozen Sections (C)

Background of CD263 / TRAILR3 antibody

TNFRSF10C is the receptor for the cytotoxic ligand TRAIL. TNFRSF10C lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. TNFRSF10C may protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated D damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additiol publications.

General readings

1. Clancy L, Mruk K, Archer K, Woelfel M, Mongkolsapaya J, Screaton G, Lenardo MJ, Chan FK: Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proc Natl Acad Sci U S A.
2005 Dec 13;102(50):18099-104.
2. Sanlioglu AD, Dirice E, Aydin C, Erin N, Koksoy S, Sanlioglu S. Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells. BMC Cancer. 2005 May 25;5(1):54.
3. Mérino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O: Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Mol Cell Biol. 2006 Oct;26(19):7046-55.
4. Falschlehner C, Emmerich CH, Gerlach B, Walczak H: TRAIL signalling: decisions between life and death. Int J Biochem Cell Biol. 2007;39(7-8):1462-75.
5. Deligezer U, Dalay N: Expression of the TRAIL Receptors in Blood Mononuclear Cells in Leukemia. Pathol Oncol Res. 2007;13(4):290-4.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD263 / TRAILR3 antibody

Western blot analysis of DcR1 in HeLa whole cell lysate with DcR1 antibody (ED) at 1:500 dilution. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD263 / TRAILR3 antibody

Western blot analysis of DcR1 in HeLa cell (A), mouse (B) and rat (C) liver tissue lysates with DcR1 antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD263 / TRAILR3 antibody

Western blot analysis of human spleen cell lysate using TNFRSF10C antibody. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD263 / TRAILR3 antibody

WB Suggested Anti-TNFRSF10C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Stomach Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 2B8 FITC Hu F, IP
0.1 mg / €400.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 2B8 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 2B8 Purified Hu F, IP
0.2 mg / €490.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 2B8 Purified Hu F, IP
25 µg / €180.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 2B8 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 TRAIL-R3-02 Azide Free Hu F
0.1 mg / €260.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 TRAIL-R3-02 FITC Hu F
0.1 mg / €340.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 TRAIL-R3-02 PE Hu F
0.1 mg / €410.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 B-H47 Azide Free Hu WB
0.2 mg / €270.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 B-D44 Azide Free Hu FN
0.2 mg / €270.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 B-D44 Purified Hu F
2ml (200 Tests) / €250.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

CD263 / TRAILR3 Mouse IgG1 B-D44 PE Hu F
1ml (100 Tests) / €290.00
  Acris Antibodies GmbH

CD263 / TRAILR3 Control Peptide

CD263 / TRAILR3
50 µg / €160.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

Immunocytochemical staining of HeLa cells wioth Rabbit anti Human CD263 (SP2114P) Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CD263 / TRAILR3 antibody

Western Blot analysis of TNFRSF10C expression in transfected 293T cell line (H00008794-T01) by TNFRSF10C MaxPab polyclonal antibody.

Lane 1: TNFRSF10C transfected lysate(28.49 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CD263 / TRAILR3 antibody

Receptor specificity of the TNFRSF10C monoclonal antibody, clone HS301 ( Cat # MAB3479 ). CV1/EBNA cells were transfected either with the empty expression vector pCDNA3 ( vector control ) or pCDNA3 encoding TNFRSF10A to TNFRSF10D. Two days after transfection, 1 X 106 cells were stained with TNFRSF10C monoclonal antibody, clone HS301 ( Cat # MAB3479 ). Mouse IgG1 HS301 Hu F, ICC/IF
0.1 mg / €730.00
  Abnova Taiwan Corp.

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