CD264 / TRAILR4 antibody

Principal name

CD264 / TRAILR4 antibody

Alternative names for CD264 / TRAILR4 antibody

TNFRSF10D, DCR2, TRAIL-R4, TRUNDD, Decoy receptor 2, TRAIL receptor 4, Tumor necrosis factor receptor superfamily member 10D, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor with a truncated death domain

SwissProt ID

Q9UBN6 (Human)

Gene ID

8793 (TNFRSF10D), 51181 (DCXR)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Rabbit, Mouse, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Immunoprecipitation (IP), Neutralisation (NEUT)

Background of CD264 / TRAILR4 antibody

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L, a member of the TNF family, induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was identified and designated DcR2 (Marsters et al., 1997; Degli-Esposti et al., 1997; Pan et al., 1998). The DcR2 receptor is 386 amino acids in length and has an extracellular TRAIL binding domain, but lacks intracellular death domain and does not induce apoptosis. Although this receptor binds to the cytotoxic ligand TRAIL, it contains a truncated death domain and functions as an inhibitory receptor. When overexpressed, the DcR2 receptor can protect cells against TRAIL mediated cytotoxicity. Like DR4 and DR5, DcR2 transcript is widely expressed in a variety of normal human tissues but DcR2 is absent in most tumors. Ultraviolet radiation has been shown to upregulate DcR2 expression on human keratinocytes. Over expression of DcR2 attenuated TRAIL induced apoptosis.

General readings

Merino, D. et al., Mol Cell Biol.,2005; 26(19): 7046-55.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD264 / TRAILR4 antibody

Western blot analysis of DcR2 in HeLa whole cell lysate with DcR2 antibody at 1:1000 dilution. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD264 / TRAILR4 antibody

Western blot analysis of extracts from Jurkat cells, using TNFRSF10D antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 Azide Free Hu F
0.1 mg / €260.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 FITC Hu F
0.1 mg / €340.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 PE Hu F
0.1 mg / €410.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 B-P30 Azide Free Hu IP, WB
0.2 mg / €270.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 B-R27 Purified Hu F
2ml (200 Tests) / €250.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 B-R27 PE Hu F
1ml (100 Tests) / €290.00
  Acris Antibodies GmbH

CD264 / TRAILR4 Control Peptide

CD264 / TRAILR4
50 µg / €160.00
  Acris Antibodies GmbH

CD264 / TRAILR4 (Center) antibody

Western blot analysis of TNFRSF10D Antibody (Center) (AP54308PU-N) in HL-60 cell line lysates (35 µg/lane). TNFRSF10D (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

Immunocytochemical staining of HeLa cells with Rabbit anti Human CD264 (SP1174P) Rabbit Purified Hu ICC/IF, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

Immunocytochemical staining of HeLa cells with Rabbit anti Human CD264 (SP1174P) Rabbit IgG Purified Hu ICC/IF, WB
50 µg / €280.00
  Acris Antibodies GmbH

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse Serum Hu E
50 µl / €290.00
  Abnova Taiwan Corp.

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 Hu F
0.1 mg / €400.00
  Abnova Taiwan Corp.

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 Hu F
0.1 mg / €470.00
  Abnova Taiwan Corp.

CD264 / TRAILR4 antibody

Immunocytochemistry staining of HeLa cells using TNFRSF10D polyclonal antibody ( Cat # PAB12831 ) at 10µg/ml. Rabbit Hu, Ms, Rt ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Goat Aff - Purified Hu E, P, WB
0.1 mg / €450.00
  Neuromics Antibodies

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 DJR4-1 Aff - Purified Hu F
0.1 mg / €380.00
  Novus Biologicals Inc.

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 Purified Hu F
0.1 mg / €360.00
  Novus Biologicals Inc.

CD264 / TRAILR4 antibody

CD264 / TRAILR4 Mouse IgG1 TRAIL-R4-01 FITC Hu F
0.1 mg / €360.00
  Novus Biologicals Inc.

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