CD265 / RANK antibody

Principal name

CD265 / RANK antibody

Alternative names for CD265 / RANK antibody

TNFRSF11A, ODFR, Tumor necrosis factor receptor superfamily member 11A, Receptor activator of NF-KB, Osteoclast differentiation factor receptor

SwissProt ID

O35305 (Mouse), Q9Y6Q6 (Human)

Gene ID

21934 (Tnfrsf11a), 8792 (TNFRSF11A)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat)

Available hosts

Rat, Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F), Functional assay (FN), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of CD265 / RANK antibody

RANK, receptor activator of NF-kappaB, also known as TRANCE receptor and osteoclast differentiation factor (ODFR), is a member of the tumor necrosis factor receptor (TNFR) family. The full-length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains. RANK is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. RANK is also expressed in dendritic cells. RANK (receptor activator of NF-kappaB) and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of RANK. TRANCE (TNF-related activation-induced cytokines, also known as RANK ligand, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for RANK. The biological functions mediated by RANK include activation of NF-kappaB and c-jun N-terminal kinase, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis. The soluble form of RANK is able to block TRANCE induced biological activity. The binding of anti-RANK to cell surface RANK triggers signal transduction and induces RANK mediated bioactivity.

General readings

Anderson DM., et al. (1997) Nature 390:175-179.Guerrini MM., et al. (2008) Am. J. Hum. Genet. 83:64-76.

Items 1 to 20 of 39 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD265 / RANK (603-613) antibody

Anti-TNFRSF11A / RANK antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Rabbit IgG Aff - Purified Hu P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

CD265 / RANK Rat R12-31 Purified Ms F
50 µg / €120.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

This antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma.  The recommended concentration is 1.0 ug/ml with an overnight incubation at 4C.  An HRP-labeled polymer detection system was used with a DAB chromogen.  Heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer is recommended.  Optimal concentrations and conditions may vary. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

Western Blot: RANK Antibody [TA336348] - Analysis of RANK in RAW cell lysate. Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

Western Blot: RANK Antibody (9A725) [TA336373] - Analysis of RANK in transfected 293 cells using RANK antibody at 2 ug/ml. Mouse IgG1 9A725 Purified Hu, Ms C, F, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

Western Blot: RANK Antibody (64C1385.1) [TA337036] - Detection of RANK in RAW cells. Lane 1. detection of RANK in RAW, a mouse cell line. Lane 2 & 3. IP/analysis of RANK. RANK protein from RAW cell lysate was immunoprecipitated either with control ant Mouse IgG1 64C1385.1 Purified Hu, Ms F, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

CD265 / RANK Rabbit Biotin Hu E
25 µg / €230.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rabbit Biotin Hu E
50 µg / €340.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rabbit Aff - Purified Hu E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rabbit Aff - Purified Hu E, FN, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rat IgG2a LOB14-8 Purified Ms E, F, IP
0.25 mg / €390.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD265 / RANK antibody

CD265 / RANK Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CD265 / RANK antibody

CD265 / RANK Mouse IgG1 2G2 Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD265 / RANK antibody

Detection of RANK in RAW cells. Lane 1. Western blot detection of RANK in RAW, a mouse cell line. Lane 2 & 3. IP/Western blot analysis of RANK. RANK protein from RAW cell lysate was immunoprecipitated either with control antibody ( lane 2 ) or TNFRSF11A monoclonal antibody, clone 64C1385.1 ( Cat # MAB0091 ) ( lane 3 ) , the immunopricipitated proteins were resolved on SDS-PAGE. RANK was detected by western blot using TNFRSF11A monoclonal antibody, clone 64C1385.1 ( Cat # MAB0091 ) . Mouse IgG1 64C1385.1 Hu, Ms F, IP
0.1 mg / €470.00
  Abnova Taiwan Corp.

CD265 / RANK antibody

CD265 / RANK Rabbit IgG Aff - Purified Hu P, WB
0.1 mg / €290.00
  Boster Immunoleader

CD265 / RANK antibody

Flow Cytometry: RANK Antibody (9A725) [NB100-56029] - Flow cytometry analysis of RANK in permeablized Raw cells using NB100-56029 at 0.625 ug/10^6 cells. The shaded histogram represents the isotype control. Mouse 9A725 PE Hu, Ms F, P, WB
0.1 mg / €330.00
  Novus Biologicals Inc.

CD265 / RANK antibody

Mouse RANK transfected cells stained with purified R12-31, followed by anti-rat IgG PE Rat IgG2a R12-31 Aff - Purified Ms F
50 µg / €320.00
  Novus Biologicals Inc.

CD265 / RANK antibody

CD265 / RANK Rat IgG2a R12-31 Aff - Purified Ms F
0.1 mg / €300.00
  Novus Biologicals Inc.

CD265 / RANK antibody

CD265 / RANK Rat IgG2a R12-31 Aff - Purified Ms F
0.5 mg / €550.00
  Novus Biologicals Inc.

Items 1 to 20 of 39 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn