CD265 / RANK antibody

Principal name

CD265 / RANK antibody

Alternative names for CD265 / RANK antibody

TNFRSF11A, ODFR, Tumor necrosis factor receptor superfamily member 11A, Receptor activator of NF-KB, Osteoclast differentiation factor receptor

SwissProt ID

O35305 (Mouse), Q9Y6Q6 (Human)

Gene ID

8792 (TNFRSF11A), 21934 (Tnfrsf11a)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Rat, Mouse

Available applications

Enzyme Immunoassay (E), Functional assay (FN), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Flow Cytometry (F), Paraffin Sections (P), Frozen Sections (C)

Background of CD265 / RANK antibody

RANK is a member of the tumor necrosis factor receptor (TNFR) family. Human and murine RANK share 81% amino acid identity in their extracellular domains. RANK is widely expressed, with highest levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. RANK is also expressed in dendritic cells. RANK and RANK ligand (RANKL) are important regulators of interactions between T cells and dendritic cells. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Multiple tumor necrosis factor receptor-associated factors (TRAFs) are involved in the signaling of RANK. TRANCE (TNF-related activation-induced cytokines, also known as RANK ligand, osteoprotegerin ligand and osteoclast differentiation factor) is the ligand for RANK. The biological functions mediated by RANK include activation of NFkappaB and cjun N-terminal kinase, enhancement of T cell growth and dendritic cell function, induction of osteoclastogenesis and lymph node organogenesis. The soluble form of RANK is able to block TRANCE induced biological activity. The binding of anti-RANK to cell surface RANK triggers signal transduction and induces RANK mediated bioactivity.

General readings

Anderson DM., et al. (1997) Nature 390:175-179.Guerrini MM., et al. (2008) Am. J. Hum. Genet. 83:64-76.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD265 / RANK (603-613) antibody

  RANK Rabbit Polyclonal (aa603-613) Antibody  
CD265 / RANK Rabbit IgG Aff - Purified Hu P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

  Rat Anti-Mouse CD265 (RANK) Purified (50 ug)  
CD265 / RANK Rat R12-31 Purified Ms F
50 µg / €120.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

  Anti-Human sRANK Receptor Rabbit Polyclonal Antibody  
This antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma.  The recommended concentration is 1.0 ug/ml with an overnight incubation at 4C.  An HRP-labeled polymer detection system was used with a DAB chromogen.  Heat induced antigen retrieval with a pH 6.0 Sodium Citrate buffer is recommended.  Optimal concentrations and conditions may vary. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

  Rabbit Polyclonal RANK/TNFRSF11A Antibody  
Western Blot: RANK Antibody [TA336348] - Analysis of RANK in RAW cell lysate. Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

  Mouse Monoclonal RANK/TNFRSF11A Antibody (9A725)  
Western Blot: RANK Antibody (9A725) [TA336373] - Analysis of RANK in transfected 293 cells using RANK antibody at 2 ug/ml. Mouse IgG1 9A725 Purified Hu, Ms C, F, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

  Mouse Monoclonal RANK/TNFRSF11A Antibody (64C1385.1)  
Western Blot: RANK Antibody (64C1385.1) [TA337036] - Detection of RANK in RAW cells. Lane 1. detection of RANK in RAW, a mouse cell line. Lane 2 & 3. IP/analysis of RANK. RANK protein from RAW cell lysate was immunoprecipitated either with control ant Mouse IgG1 64C1385.1 Purified Hu, Ms F, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD265 / RANK antibody

CD265 / RANK Rabbit Biotin Hu E
25 µg / €230.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rabbit Biotin Hu E
50 µg / €340.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rabbit Aff - Purified Hu E, FN, WB
50 µg / €230.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rabbit Aff - Purified Hu E, FN, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD265 / RANK antibody

CD265 / RANK Rat IgG2a LOB14-8 Purified Ms E, F, IP
0.25 mg / €390.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Tnfrsf11a - mouse gene knockout kit via CRISPR

Tnfrsf11a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Tnfrsf11a - mouse gene knockout kit via CRISPR

Tnfrsf11a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnfrsf11a - mouse gene knockout kit via CRISPR

Tnfrsf11a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tnfrsf11a - mouse gene knockout kit via CRISPR

Tnfrsf11a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD265 / RANK

  Purified recombinant protein of Human tumor necrosis factor receptor superfamily, member 11a, NFKB activator (TNFRSF11A).  
CD265 / RANK Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

CD265 / RANK (28-212, His-tag)

CD265 / RANK Human Purified > 90 % by SDS – PAGE Insect cells
0.25 mg / €940.00
  Acris Antibodies GmbH

CD265 / RANK (28-212, His-tag)

CD265 / RANK Human Purified > 90 % by SDS – PAGE Insect cells
50 µg / €300.00
  Acris Antibodies GmbH

ELISA Kits

Catalog No.    

Mouse RANK ELISA Kit

Mouse RANK ELISA Kit  
1 kit / €420.00
  OriGene Technologies, Inc.

OmniKine™ Human sRANK Ligand ELISA Kit

OmniKine™ Human sRANK Ligand ELISA Kit  
96 Tests / €440.00
  Assay Biotech

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