CD268 / BAFFR antibody

Principal name

CD268 / BAFFR antibody

Alternative names for CD268 / BAFFR antibody

BAFF receptor, BLyS receptor 3, TNFRSF13C, BR3, BAFF-R, Tumor necrosis factor receptor superfamily member 13C, B cell-activating factor receptor

SwissProt ID

Q96RJ3 (Human), Q9D8D0 (Mouse)

Gene ID

115650 (TNFRSF13C), 72049 (Tnfrsf13c)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Rat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), ELISA (detection) (E(detection)), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD268 / BAFFR antibody

BAFF receptor (B cell activating factor receptor) is a 19 kD type III membrane protein that is a member of the TNF receptor superfamily. The primary responsibility for BAFF R is the mediating role of BAFF in B-cell survival and maturation. BAFF R is one of three different receptors (also includes TACI and BCMA) specific for BAFF and plays a predominant role in BAFF induced B-cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kappaB and c-jun N terminal kinase. BAFF/BAFF receptors appear to span nearly all stages of Blineage differentiation, ranging from the development, selection, and homeostasis of naive primary B cells to the maintenance of long-lived bone marrow plasma cells. The dysregulation of BAFF/BAFF receptor system may contribute to induction and development of autoimmune diseases and become one of important therapeutic targets. This is a HCX protein. HCX Expression System Details HCX proteins mimic the proteins in the human body because they are expressed from human, rather than animal, insect or bacterial cells. This process gives them human post-translational modifications. Recombinant DNA techniques allow a human protein with the correct amino acid sequence to be expressed in a non-human cell line. However, non-human cells lack the appropriate cellular machinery, such as specific glycosyltransferases, necessary to produce the correct human post-translational modifications of a protein. An extreme example is seen in E. coli cells, which produce recombinant proteins with no glycosylation, as the above figure illustrates. Rodent and yeast cells are able to glycosylate proteins, but they are still different from glycosylation in human cells. Expression System Resultant Proteins Human (e.g. K562, HEK293) Correct amino acid sequence Human post-translational modifications Rodent (e.g. CHO, NSO) Correct amino acid sequence Some natural glycosylation - not human-like Yeast (e.g. Pichia) Correct amino acid sequence Some natural glycosylation - not human-like E.Coli Correct amino acid sequence No PTMs Although there have been significant attempts to make non-human cell derived cytokines more human-like, there is a growing awareness that in many instances, particularly in therapeutics, cytokines should mimic those found in the body as closely as possible.

General readings

So et al. (2006) Int J Hematol. 83(1):1-11

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD268 / BAFFR (C-term) antibody

Western blot analysis of BAFF Receptor in human (H), mouse (M), and rat (R) spleen tissue lysates with BAFF Receptor antibody at 5 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD268 / BAFFR antibody

Tonsil: Formalin-Fixed Paraffin-Embedded (FFPE) Mouse IgG1 11C1 Aff - Purified Hu F, P
50 µg / €470.00
  Acris Antibodies GmbH

CD268 / BAFFR antibody

Immunohistochemical detection of BAFF-R/BR3 on paraffin embedded section of BAFF-R/BR3 transfected cells (left) and mock transfected cells (right) with AM26519AF-N. Mouse IgG2a 8A7 Azide Free Hu F, P, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CD268 / BAFFR antibody

Flow cytometric analysis of BAFF-R/BR3 expression on BAFF-R/BR3 transfected cells (right) and parental cells (left). Open histogram indicate the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26519FC-N to the cells. Mouse IgG2a 8A7 FITC Hu F
0.1 ml / €340.00
  Acris Antibodies GmbH

CD268 / BAFFR antibody


Flow cytometric analysis of CD268/BAFF-R/BR3 expression on Raji (left) and Jurkat (right). Open histograms indicate the reaction of isotypic control to the cells. Shaded hist ograms indicate the reaction of AM26519RP-N to the cells.
Mouse IgG2a 8A7 PE
50 Tests / €360.00
  Acris Antibodies GmbH

CD268 / BAFFR Control Peptide

CD268 / BAFFR
50 µg / €160.00
  Acris Antibodies GmbH

CD268 / BAFFR (C-term) antibody

Immunohistochemical staining of human tonsil with Rabbit anti CD286 (SP2134P) Rabbit Purified Hu, Ms, Rt P, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

CD268 / BAFFR antibody

CD268 / BAFFR Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD268 / BAFFR antibody

TNFRSF13C MaxPab rabbit polyclonal antibody. Western Blot analysis of TNFRSF13C expression in mouse kidney. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD268 / BAFFR antibody

Detection of endogenous TNFRSF13C in a human palatine tonsil paraffin section stained with the monoclonal antibody to TNFRSF13C monoclonal antibody, clone 11CC1 ( Cat # MAB3717 ). An intense staining of B cell follicles and weaker staining of germinal center is observed ( X200 ). Mouse IgG1 11CC1 Hu C, F, P
0.1 mg / €640.00
  Abnova Taiwan Corp.

CD268 / BAFFR antibody

CD268 / BAFFR Rat IgG1 7H22-E16 Ms F, WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

CD268 / BAFFR antibody

Western blot analysis of Tnfrsf13c expression in rat kidney tissue lysate. Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CD268 / BAFFR antibody

Immunohistochemistry of TNFRSF13C in human tonsil tissue with TNFRSF13C polyclonal antibody ( Cat # PAB12894 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD268 / BAFFR antibody

CD268 / BAFFR Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

CD268 / BAFFR antibody

Flow Cytometry: CD268 Antibody (11C1) [NB100-77991] - Human peripheral blood lymphocytes stained with 11C1 FITC Mouse IgG1 11C1 FITC Hu F
100 Tests / €360.00
  Novus Biologicals Inc.

CD268 / BAFFR antibody

Immunohistochemistry: BAFF Receptor Antibody (11C1) [NB120-16232] - Immunohistochemistry staining of human tonsil with NB120-16232, showing intense staining of B cell follicles and weaker staining on GC. Magnification X200. Mouse IgG1 11C1 Aff - Purified Hu F, P
0.1 mg / €380.00
  Novus Biologicals Inc.

CD268 / BAFFR antibody

CD268 / BAFFR Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

CD268 / BAFFR antibody

Immunohistochemistry-Paraffin: BAFF Receptor Antibody [NBP1-90011] - Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD268 / BAFFR

CD268 / BAFFR Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 50 µg / €199.00

Special Price: 50 µg / €139.00

  OriGene Technologies, Inc.

CD268 / BAFFR

CD268 / BAFFR Human Purified > 95 % pure by SDS-PAGE gel and HPLC analyses E. coli
50 µg / €230.00
  Acris Antibodies GmbH

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