CD269 / BCMA antibody

Principal name

CD269 / BCMA antibody

Alternative names for CD269 / BCMA antibody

TNFRSF17, BCM, Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein

SwissProt ID

O88472 (Mouse), Q02223 (Human)

Gene ID

608 (TNFRSF17), 21935 (Tnfrsf17)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Rat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), EPair for Elisa (EPair), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Neutralisation (NEUT)

Background of CD269 / BCMA antibody

BCMA, a member of the TNF receptor superfamily, binds to BAFF and APRIL. BCMA is expressed on mature B-cells and other B-cell lines and plays an important role in B cell development, function and regulation. BCMA also has the capability to activate NF-kappaB and JNK. The human BCMA gene codes for a 184 amino acid type I transmembrane protein, which contains a 54 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 107 amino acid extracellular domain.
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL1/THANK/zTNF4 and April/TALL2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFFR, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

General readings

Chae S C., et al. (2010) Mol Cells. 29(1): 21-8Barone F., et al. (2009) Mucosal Immunol. 2(6): 495-503.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD269 / BCMA antibody

Western blot analysis of BCMA in human spleen (A) tissue lysate, K562 (B), and U937 (C) cell lysates with BCMA antibody at 5 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD269 / BCMA antibody

Western blot analysis of extracts from K562 cells and JK cells, using TNFRSF17 Antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD269 / BCMA antibody

Western blot analysis of BCMA expression in K562 (Lane 1) and U937 (Lane 2) cell lysate. Rabbit Aff - Purified Hu P, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

CD269 / BCMA (C-term) antibody

Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu C, E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD269 / BCMA Control Peptide

CD269 / BCMA
50 µg / €160.00
  Acris Antibodies GmbH

CD269 / BCMA (Center) antibody

TNFRSF17 Antibody (Center) (AP54310PU-N) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the TNFRSF17 antibody detected the TNFRSF17 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD269 / BCMA antibody

Western Blot analysis of TNFRSF17 expression in transfected 293T cell line (H00000608-T01) by TNFRSF17 MaxPab polyclonal antibody.

Lane 1: TNFRSF17 transfected lysate(20.24 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

Immunoprecipitation of TNFRSF17 transfected lysate using anti-TNFRSF17 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TNFRSF17 MaxPab mouse polyclonal antibody (B01) (H00000608-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

Western Blot analysis of TNFRSF17 expression in transfected 293T cell line (H00000608-T02) by TNFRSF17 MaxPab polyclonal antibody.

Lane 1: TNFRSF17 transfected lysate(20.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

Detection limit for recombinant GST tagged TNFRSF17 is approximately 0.3ng/ml as a capture antibody. Mouse IgG1 1F10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

Western Blot analysis of TNFRSF17 expression in transfected 293T cell line by TNFRSF17 monoclonal antibody (M06), clone 3H6.

Lane 1: TNFRSF17 transfected lysate(20.1 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 3H6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

FACS analysis of cells using antibody to Tnfrsf17 monoclonal antibody, clone Vicky-2 ( Cat # MAB3374 ). HEK 293 cells were mock transfected ( thin line ) or transfected with an expression plasmid coding for mouse Tnfrsf17 ( thick line ). Rat IgG2a Vicky-2 Ms F, IP, WB
0.1 mg / €640.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

Western blot analysis of TNFRSF17 expression in K-562 ( Lane 1 ) and U-937 ( Lane 2 ) cell lysate. Rabbit Hu C, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

CD269 / BCMA antibody

CD269 / BCMA Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

CD269 / BCMA antibody

Immunohistochemistry-Paraffin: BCMA Antibody [NBP1-90001] - Immunohistochemical staining of human lymph node shows moderate granular positivity in reaction center cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD269 / BCMA

CD269 / BCMA Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli

Regular Price: 20 µg / €199.00

Special Price: 20 µg / €139.00

  OriGene Technologies, Inc.

CD269 / BCMA (78-184, His-tag)

CD269 / BCMA Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CD269 / BCMA (78-184, His-tag)

CD269 / BCMA Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CD269 / BCMA

CD269 / BCMA Human Purified > 98 % pure by SDS-PAGE and HPLC analyses E. coli
5 µg / €140.00
  Acris Antibodies GmbH

CD269 / BCMA

CD269 / BCMA Human Purified > 98 % pure by SDS-PAGE and HPLC analyses E. coli
20 µg / €230.00
  Acris Antibodies GmbH

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