CD280 / MRC2 antibody

Principal name

CD280 / MRC2 antibody

Alternative names for CD280 / MRC2 antibody

C-type mannose receptor 2, ENDO180, KIAA0709, UPARAP, UPAR-associated protein, Urokinase receptor-associated protein, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein

SwissProt ID

Q4TU93 (Rat), Q64449 (Mouse), Q9UBG0 (Human)

Gene ID

9902 (MRC2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F)

Background of CD280 / MRC2 antibody

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

General readings

Messaritou, G. et al., J. Cell. Sci. 122 (PT 22): 4042-4048 (2009)
Wu, X. et al., Cancer Prev Res (Phila Pa) 2(7): 617-624 (2009)
Wienke, D. et al., Cancer Res. 67(21): 10230-10240 (2007)
Sulek, J. et al., J. Histochem. Cytochem. 55(4): 347-353 (2007)
Johnson, J.M. et al., Science 302(5653): 2141-2144 (2003)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD280 / MRC2 antibody

Western blot analysis of extracts from 293 cells, using MRC2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD280 / MRC2 antibody

Western blot analysis on 293 cell lysate using MRC2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD280 / MRC2 (Center) antibody

Western blot analysis in NCI-H460 cell line lysates (35ug/lane) using CD280 / MRC2 antibody Cat.-No. AP52744PU-N. This demonstrates this antibody detected the MRC2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD280 / MRC2 antibody

CD280 / MRC2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CD280 / MRC2 antibody

Western Blot detection against Immunogen (37.84 KDa) Mouse IgG2a 2D7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD280 / MRC2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MRC2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

CD280 / MRC2 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MRC2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

CD280 / MRC2 antibody

CD280 / MRC2 Rabbit IgG Hu WB
0.1 ml / €340.00
  Novus Biologicals Inc.

CD280 / MRC2 antibody

CD280 / MRC2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CD280 / MRC2 antibody

CD280 / MRC2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

CD280 / MRC2 antibody

Immunohistochemistry-Paraffin: MRC2 Antibody [NBP1-85768] Immunohistochemical staining of human small intestine shows moderate cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD280 / MRC2

CD280 / MRC2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CD280 / MRC2

CD280 / MRC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CD280 / MRC2

CD280 / MRC2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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