CD29 / Integrin beta-1 antibody

Principal name

CD29 / Integrin beta-1 antibody

Alternative names for CD29 / Integrin beta-1 antibody

Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, ITGB1, FNRB, MDF2, MSK12

SwissProt ID

P05556 (Human), P07228 (Chick), P09055 (Mouse), P49134 (Rat), P53712 (Bovin), P53713 (Felca), Q9GLP0 (Pig)

Gene ID

3688 (ITGB1), 16412 (Itgb1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine), Bov (Bovine), Mky (Monkey), Rb (Rabbit), Chk (Chicken), Sh (Sheep), Eq (Equine)

Available hosts

Rabbit, Mouse, Hamster, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Functional assay (FN), ELISA (detection) (E(detection)), Activity Assay (ACT), Neutralisation (NEUT)

Background of CD29 / Integrin beta-1 antibody

Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1/RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis

General readings

1. Noto, K. et al. (1995) Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7: 835-842.
2. Lu, T.Y. et al. (2010) Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells.
J Biol Chem. 285: 8719-32.
3. Li, S. et al. (2010) Upregulation of CXCR4 favoring neural-like cells migration via AKT activation.
Neurosci Res. 2010 Apr 20. [Epub ahead of print]
4. Tiede, B.J. et al. (2009) A novel mouse model for non-invasive single marker tracking of mammary stem cells in vivo reveals stem cell dynamics throughout pregnancy. PLoS ONE. 4: 1-9.
5. Eto, D.S. et al. (2007) Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
PLoS Pathog. 3: e100.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD29 / Integrin beta-1 antibody

SM2118P ITGB1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Prostate at 10 μg/ml after heat-induced antigen retrieval. Mouse IgG2a JB1B Ig Fraction Hu, Mky C, E, F, IP, P, WB
0.2 mg / €460.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Surface staining of human peripheral blood with anti-human CD29 (MEM-101A) APC. Mouse IgG1 MEM-101A FITC Can, Hu, Por F
100 Tests / €260.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues (left) and cervical cancer tissues (right) using ITGB1 antibody Cat.-No AM06734PU-N with DAB staining. Mouse IgG1 3B6 Purified Hu, Mky E, F, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Western blot analysis using ITGB1 antibody Cat.-No AM06735PU-N against human ITGB1 (AA: 50-270) recombinant protein (Expected MW is 50.6 kDa). Mouse IgG1 3B6B2 Purified Hu E, F, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Immunohistochemistry: AM09002PU-N CD29 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Prostate at 10 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG1 k2D5 Purified Hu E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Immunohistochemistry: AM09002PU-N CD29 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Prostate at 10 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG1 k2D5 Purified Hu E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Immunohistochemistry: Integrin beta 1 Antibody (EPR1040Y) [NB100-79981] - Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma using anti-Integrin beta 1. Rabbit IgG EPR1040Y Hu F, P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

CD29 / Integrin beta-1 antibody

Western blot analysis of extracts from Jurkat cells, using Integrin ß1 (Ab-789) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 antibody

Staining of C57Bl/6 thymocytes with 0.5 ug of Armenian Hamster IgG Isotype Control Purified (open histogram) or 0.5 ug of Anti-Mouse/Rat CD29 Purified (filled histogram) followed by Anti-Armenian Hamster IgG Biotin and Streptavidin PE .  Total viable cells were used for analysis. Hamster eBioHMb1-1 (HMb1-1) Purified Ms, Rt F, IP
50 µg / €120.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 antibody

Balb/c spleen cell lysate (3x10e5 cells/lane) was resolved by SDS-PAGE under non-reducing conditions, immunoblotted with 2 ug/mL Anti-Mouse CD29 Purified and revealed with Anti-Rat IgG HRP. Rat KMI6 Purified Ms F, IP, P, WB
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 antibody

Staining of normal human peripheral blood cells with 0.125 ug of Mouse IgG1 kappa Isotype Control Purified  (blue histogram) or 0.125 ug of Anti-Human CD29 Purified (purple histogram) followed by F(ab')2 Anti-Mouse IgG PE .  Cells in the lymphocyte gate were used for analysis. Mouse TS2/16 Purified Hu F, IP, P
0.1 mg / €130.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 antibody

ITGB1 Antibody (Cat. #TA328165) western blot analysis in U87-MG cell line lysates (35ug/lane).This demonstrates the ITGB1 antibody detected the ITGB1 protein (arrow). Mouse IgG1 1084CT17.4.1 Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 (Extracell. Dom.) antibody

Anti-Integrin Beta 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 (Extracell. Dom.) antibody

Anti-Integrin Beta 1 antibody IHC of human placenta, terminal villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 antibody

Western blot analysis of Integrin ß1 expression in Jurkat cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD29 / Integrin beta-1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITGB1 (RC203818, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITGB1. Mouse IgG1 OTI2A3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD29 / Integrin beta-1 antibody

Flow cytometric analysis of CD29/β1 Integrin expression on MOLT-4 (left) and Jurkat (right). Open histograms indicate the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26428AF-N to the cells. Mouse IgG1 AG89 Azide Free Hu F, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

Flow cytometric analysis of Human β1-Integrin expression on MOLT-4 cells (left) and Jurkat cells (right). Open histograms indicate the reaction of isotypic control to the cells. Shaded histograms indicate the reaction of AM26428RP-N to the cells. Mouse IgG1 AG89 PE Hu F
50 Tests / €340.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

A typical staining pattern with the B-D15 monoclonal antibody of lymphocytes Mouse IgG2a B-D15 Azide Free Hu P
0.2 mg / €270.00
  Acris Antibodies GmbH

CD29 / Integrin beta-1 antibody

A typical staining pattern with the B-D15 monoclonal antibody of lymphocytes Mouse IgG2a B-D15 FITC Hu F
1ml (100T) / €270.00
  Acris Antibodies GmbH

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