CD292 / BMPR1A antibody

Principal name

CD292 / BMPR1A antibody

Alternative names for CD292 / BMPR1A antibody

ACVRLK3, ALK3, ALK-3, SKR5, Bone morphogenetic protein receptor type-1A, Serine/threonine-protein kinase receptor R5, Activin receptor-like kinase 3

SwissProt ID

P36894 (Human), P36895 (Mouse), Q78EA7 (Rat)

Gene ID

657 (BMPR1A), 12166 (Bmpr1a), 81507

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CD292 / BMPR1A antibody

The bone morphogenetic protein (BMP) receptors belong to a family of transmembrane serine/threonine kinases including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. Both activins and TGF-beta transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMP receptors are highly expressed in bone, skeletal muscle, heart and liver tissue. BMPRs play a crucial role during development as mutations or deletions to the BMPR genes can cause juvenile polyposis, disrupt normal dorsal/ventral patterning during limb development, and may be a factor in the progession of Cowden-like syndrome. Germline mutations in the BMPR2 gene encoding bone morphogenetic protein (BMP) type II receptor (BMPR-II) have been reported in patients with primary pulmonary hypertension (PPH).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD292 / BMPR1A antibody

  Goat Polyclonal Antibody against BMPR1A  
TA303097 (1µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD292 / BMPR1A antibody

  Rabbit anti-BMPR1A Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using BMPR1A antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD292 / BMPR1A (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD292 / BMPR1A (N-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD292 / BMPR1A (Center) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD292 / BMPR1A (N-term) antibody

The anti-BMPR1A (AP11859PU-N) is used in Western blot to detect BMPR1A in mouse muscle tissue lysate (Lane 1) and Hela cell lysate (Lane 2). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD292 / BMPR1A (N-term) antibody

Western blot analysis of anti-BMPR1A Antibody (N-term) (AP11860PU-N) in mouse kidney tissue lysates (35 µg/lane). BMPR1A (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

BMPR1A - human gene knockout kit via CRISPR

BMPR1A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BMPR1A - human gene knockout kit via CRISPR

BMPR1A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

BMPR1A - human gene knockout kit via CRISPR

BMPR1A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

BMPR1A - human gene knockout kit via CRISPR

BMPR1A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bmpr1a - mouse gene knockout kit via CRISPR

Bmpr1a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Bmpr1a - mouse gene knockout kit via CRISPR

Bmpr1a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bmpr1a - mouse gene knockout kit via CRISPR

Bmpr1a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Bmpr1a - mouse gene knockout kit via CRISPR

Bmpr1a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD292 / BMPR1A

  Recombinant protein of human bone morphogenetic protein receptor, type IA (BMPR1A)  
CD292 / BMPR1A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CD292 / BMPR1A

  Purified recombinant protein of Human bone morphogenetic protein receptor, type IA (BMPR1A)  
CD292 / BMPR1A Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

CD292 / BMPR1A

SDS-PAGE analysis of recombinant human soluble BMPR-1A from insect cells. Sample was loaded in 15% SDS-polyacrylamide gel under reducing condition and stained with Silver stain. Human Purified > 90 % pure by SDS-PAGE and silver staining Insect cells
0.1 mg / €330.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

BMPR1A overexpression lysate

BMPR1A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Lysates (Knockout)

Catalog No.    

BMPR1A knockout Cell lysate

BMPR1A knockout Cell lysate  
0.1 mg / €495.00
  OriGene Technologies, Inc.

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