CD294 / GPR44 antibody

Principal name

CD294 / GPR44 antibody

Alternative names for CD294 / GPR44 antibody

CRTH2, DL1R, PTGDR2, Prostaglandin D2 receptor 2, G-protein coupled receptor 44, Chemoattractant receptor-homologous molecule expressed on Th2 cells

SwissProt ID

Q6XKD3, Q9Y5Y4 (Human), Q9Z2J6 (Mouse)

Gene ID

11251 (PTGDR2), 14764 (Gpr44)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Prim (Primate), Bov (Bovine), Can (Canine), Mky (Monkey), Rb (Rabbit), Eq (Equine), Bear, Gorilla

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD294 / GPR44 antibody

GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.
CRTH2 has been reported to be expressed in the central nervous system, peripheral tissues, and in blood cells, particularly activated T helper-2 cells. Two transcripts have been isolated, a 3.5-kb transcript expressed primarily in the thalamus, frontal cortex, pons, and hippocampus, and a 3.4-kb transcript expressed in fetal liver, leukocytes, and thymus. ESTs have been isolated from B-cell/lung/testis, brain, kidney, liver/spleen, placenta, prostate, testis, and thymus libraries.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD294 / GPR44 (N-term) antibody

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GPR44 antibody AP22663PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD294 / GPR44 (N-term) antibody

  Rabbit Polyclonal CRTH2 Antibody  
Western blot analysis of CRTH2 in Jurkat cell lysate with CRTH2 antibody at 1 ug/ml in (A) the absence and (B) presence of blocking peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD294 / GPR44 (Center) antibody

  Rabbit Polyclonal CRTH2 Antibody  
Western blot analysis of CRTH2 in human heart tissue lysate with CRTH2 antibody at (A) 1 and (B) 2 ug/ml. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD294 / GPR44 (N-term Extracel. Dom.) antibody

  GPR44 / CRTH2 Rabbit Polyclonal (N-Terminus) Antibody  
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Can, Hu, Mky, Por, Prim, Rb ICC/IF, P
50 µg / €345.00
  OriGene Technologies, Inc.

CD294 / GPR44 (2nd Extracell. Dom.) antibody

  GPR44 / CRTH2 Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-GPR44 / CRTH2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Can, Elephant, Eq, Hu, Mky, Ms, Por, Prim, Rb, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

CD294 / GPR44 (3rd Extracell. Dom.) antibody

  GPR44 / CRTH2 Rabbit Polyclonal (Extracellular Domain) Antibody  
Anti-GPR44 / CRTH2 antibody IHC of human nasal mucosa, eosinophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Can, Elephant, Eq, Hu, Mky, Prim ICC/IF, P
50 µg / €345.00
  OriGene Technologies, Inc.

CD294 / GPR44 (C-term, cytopl. dom.) antibody

  GPR44 / CRTH2 Rabbit Polyclonal (C-Terminus) Antibody  
Anti-GPR44 / CRTH2 antibody IHC of human tonsil mast cell. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Gorilla, Hu, Por E, P
50 µg / €345.00
  OriGene Technologies, Inc.

CD294 / GPR44 antibody

  Rabbit Polyclonal PTGDR2 Antibody  
Western blot analysis of PTGDR2 in small intestine tissue lysate with PTGDR2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD294 / GPR44 antibody

  Rabbit Polyclonal CRTH-2/GPR44 Antibody  
Western Blot: GPR44 Antibody [TA336504] - Analysis of GPR44 in GPR44 transfected Jurkat cells using GPR44 antibody at 1:500 dilution. Does not detect GPR44 in non-transfected parental Jurkat cells. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD294 / GPR44 (329-348) antibody

Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Elephant, Hu, Por, Prim E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CD294 / GPR44 control peptide

Western blot analysis of CRTH2 in Jurkat cell lysate with CRTH2 antibody at 1 μg/ml in (A) the absence and (B) presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

CD294 / GPR44 control peptide

CD294 / GPR44
50 µg / €160.00
  Acris Antibodies GmbH

CD294 / GPR44 antibody

Immunohistochemistry of GPR44 in human heart tissue with GPR44 polyclonal antibody ( Cat # PAB13243 ) at 2.5 µg/ml. Rabbit IgG Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CD294 / GPR44 antibody

Immunohistochemistry of GPR44 in human heart tissue with GPR44 polyclonal antibody ( Cat # PAB13244 ) at 2.5 µg/ml. Rabbit IgG Hu, Ms, Rt P
0.1 mg / €390.00
  Abnova Taiwan Corp.

CRISPR

Catalog No. Species Donor Vector  

Gpr44 - mouse gene knockout kit via CRISPR

Gpr44 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Gpr44 - mouse gene knockout kit via CRISPR

Gpr44 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpr44 - mouse gene knockout kit via CRISPR

Gpr44 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Gpr44 - mouse gene knockout kit via CRISPR

Gpr44 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

PTGDR2 overexpression lysate

PTGDR2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, PTGDR2 (mGFP-tagged) - Human G protein-coupled receptor 44 (GPR44), 200 uL, >10^7 TU/mL

Lenti ORF particles, PTGDR2 (mGFP-tagged) - Human G protein-coupled receptor 44 (GPR44), 200 uL, >10^7 TU/mL  
200 µl / €970.00
  OriGene Technologies, Inc.

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