CD30 antibody

Principal name

CD30 antibody

Alternative names for CD30 antibody

TNFRSF8, D1S166E, CD30L receptor, KI-1 antigen, Tumor necrosis factor receptor superfamily member 8, Lymphocyte activation antigen CD30

SwissProt ID

P28908 (Human), P97525 (Rat), Q60846 (Mouse)

Gene ID

21941 (Tnfrsf8), 943 (TNFRSF8), 25069

Available reactivities

Ms (Mouse), Hu (Human), Mky (Monkey)

Available hosts

Rat, Mouse, Hamster, Rabbit

Available applications

Flow Cytometry (F), Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Functional assay (FN), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CD30 antibody

CD30 is a type I transmembrane glycoprotein of the TNF receptor superfamily. CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1. The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor. Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response.

General readings

1. Lenze, D., et al., Blood 107, 1141-1148 (2006)
2. Claviez, A., et al., J. Clin. Oncol. 23, 4048-4056 (2005)
3. Nagata, S., et al., PNAS 102, 7946-7951 (2005)
4. Simonitsch, K., et al., J. Clin. Oncol. 21, 1782-1789 (2003)
5. Bartek, J., et al., Haematologica. 84, 988-995 (1999)
6. Latza, U., et al., Am. J. Pathol. 3, 463-471 (1995)
7. Schwarting, R., et al., Blood 74, 1678-1689 (1989)
Clone Ber-H2 is used in these references.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD30 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801630) Mouse IgG1 OTI1C6 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801647) Mouse IgG2a OTI18D3 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801685) Mouse IgG1 OTI16H5 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801686) Mouse IgG1 OTI9H7 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA804018) Mouse IgG1 OTI3A2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA804021) Mouse IgG1 OTI2G7 Purified Hu F, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Western blot analysis using CD30 mAb against human CD30 (AA: 536-590) recombinant protein. (Expected MW is 32 kDa) Mouse IgG1 3B10 Ascites Hu E, F, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CD30 antibody

Immunohistochemistry: AM20190AF-N CD30 antibody staining of Paraffin Embedded CCRF-CEM Section. Mouse IgG1 Ber-H2 Azide Free Hu F, IP, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CD30 antibody

Formalin-Fixed, Paraffin-Embedded Hodgkin's lymphoma (20X) stained with CD30 Antibody Cat.-No AM32849PU (Clone CD30/412). Mouse IgG2b CD30/412 Purified Hu C, F, ICC/IF, IP, P
0.2 mg / €390.00
  Acris Antibodies GmbH

CD30 antibody

Formalin-Fixed, Paraffin-Embedded Hodgkin's lymphoma (20X) stained with CD30 Antibody Cat.-No AM32849PU (Clone CD30/412). Mouse IgG2b CD30/412 Purified Hu C, F, ICC/IF, IP, P
0.1 mg / €320.00
  Acris Antibodies GmbH

CD30 antibody

Formalin-Fixed, Paraffin-Embedded Hodgkin's lymphoma (20X) stained with CD30 Antibody Cat.-No AM32849PU (Clone CD30/412). Mouse IgG2b CD30/412 Purified Hu C, F, ICC/IF, IP, P
20 µg / €160.00
  Acris Antibodies GmbH

CD30 antibody

CD30 Hamster mCD30.1 Purified Ms F
0.1 mg / €120.00
  OriGene Technologies, Inc.

CD30 antibody

  Mouse Monoclonal TNFRSF8 (CD30) Antibody  
Immunohistochemistry staining of Paraffin Classic Hodgkin lymphoma tissue by CD30 antibody (dilution: 1:50 - 1:200; visualization of staining: Membranous) Mouse IgG1 Ber-H2 Purified Hu P
1 ml / €390.00
  OriGene Technologies, Inc.

CD30 antibody

CD30 Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD30 antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-TNFRSF8 rabbit polyclonal antibody. (TA590389) Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD30 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF8 (RC219819, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNFRSF8. Mouse IgG2a OTI2G2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-TNFRSF8 mouse monoclonal antibody. (TA801726) Mouse IgG1 OTI3B5 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF8 (RC219819, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNFRSF8. Mouse IgG1 OTI4B3 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF8 (RC219819, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNFRSF8. Mouse IgG1 OTI3B10 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD30 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNFRSF8 (RC219819, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNFRSF8. Mouse IgG1 OTIF8 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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