CD300A / CMRF35H antibody

Principal name

CD300A / CMRF35H antibody

Alternative names for CD300A / CMRF35H antibody

CLM-8, CMRF35-H, CMRF35-H9, CMRF-35-H9, IRC1/IRC2, IRp60, CMRF35-like molecule 8, Inhibitory receptor protein 60, NK inhibitory receptor, CD300 antigen-like family member A

SwissProt ID

A2TGX5 (Rat), Q6SJQ0 (Mouse), Q9UGN4 (Human)

Gene ID

11314 (CD300A), 217303 (Cd300a)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F)

Background of CD300A / CMRF35H antibody

Immune responses are regulated by opposing positive and negative signals triggered by the interaction of activating and inhibitory cell surface receptors with their ligands. Shibuya et al. identified novel paired activated and inhibitory immunoglobulin-like receptors, designated myeloid-associated immunoglobulin-like receptor (MAIR) I and MAIR-II, whose extracellular domains are highly conserved by each other. MAIR-I, expressed on the majority of myeloid cells, including macrophages, granulocytes, mast cells, and dendritic cells, contains the tyrosine-based sorting motif and the immunoreceptor tyrosine-based inhibitory motif-like sequences in the cytoplasmic domains. On the other hand, MAIR-II, expressed on subsets of peritoneal macrophages and B cells, associates with the immunoreceptor tyrosine-based activation motif-bearing adaptor DAP12. MAIR-I is also known as CD300a/ CMRF-35-like Ig-like molecule-8 (CLM-8)/leukocyte mono-Ig-like receptor 1 (LMIR1). MAIR-II is also known as CD300d/LMIR2/CLM-4/dendritic cell-derived Ig-like receptor 1 (DIgR1).

General readings

Clark G.J., et al. (2000) Tissue Antigens. 55:101-109Bachelet I., et al. (2005) J. Immunol. 175:7989-7995

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD300A / CMRF35H antibody

Surface staining of human peripheral blood cells with anti-CD300a (MEM-260) PE. Mouse IgG1 MEM-260 Purified Hu F, WB
0.1 mg / €230.00
  Acris Antibodies GmbH

CD300A / CMRF35H antibody

Surface staining of human peripheral blood cells with anti-CD300a antibody AM03062RP-N (MEM-260, PE conjugated). Mouse IgG1 MEM-260 PE Hu F
100 Tests / €290.00
  Acris Antibodies GmbH

CD300A / CMRF35H antibody

Flow cytometric analysis of mouse CD300a expression on WEHI-3B cells. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of AM26506AF-N to the cells. Rat IgG2a TX40 Azide Free Ms F
0.1 mg / €400.00
  Acris Antibodies GmbH

CD300A / CMRF35H antibody

Flow cytometric analysis of mouse CD300a (MAIR-I) expression on WEHI-3B cells. Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of AM26506FC-N to the cells. Rat IgG2a TX40 FITC Ms F
0.1 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CD300A - human gene knockout kit via CRISPR

CD300A - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CD300A - human gene knockout kit via CRISPR

CD300A - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CD300A - human gene knockout kit via CRISPR

CD300A - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CD300A - human gene knockout kit via CRISPR

CD300A - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd300a - mouse gene knockout kit via CRISPR

Cd300a - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cd300a - mouse gene knockout kit via CRISPR

Cd300a - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd300a - mouse gene knockout kit via CRISPR

Cd300a - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cd300a - mouse gene knockout kit via CRISPR

Cd300a - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD300A / CMRF35H

  Purified recombinant protein of Human CD300a molecule (CD300A)  
CD300A / CMRF35H Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

CD300A / CMRF35H (18-128, His-tag)

CD300A / CMRF35H Human Purified > 90 % by SDS - PAGE E. coli
0.25 mg / €730.00
  Acris Antibodies GmbH

CD300A / CMRF35H (18-128, His-tag)

CD300A / CMRF35H Human Purified > 90 % by SDS - PAGE E. coli
50 µg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

CD300A overexpression lysate

CD300A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cd300a (GFP-tagged) - Mouse CD300A antigen (Cd300a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cd300a (GFP-tagged) - Mouse CD300A antigen (Cd300a), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cd300a (Myc-DDK-tagged) - Mouse CD300A antigen (Cd300a), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cd300a (Myc-DDK-tagged) - Mouse CD300A antigen (Cd300a), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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