CD301 / CLEC10A antibody

Principal name

CD301 / CLEC10A antibody

Alternative names for CD301 / CLEC10A antibody

CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectin superfamily member 14, Macrophage lectin 2

SwissProt ID

Q8IUN9 (Human)

Gene ID

10462 (CLEC10A)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat)

Available hosts

Rat, Mouse, Rabbit

Available applications

Frozen Sections (C), Flow Cytometry (F), Functional assay (FN), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of CD301 / CLEC10A antibody

ASGPR/MGL (asialoglycoprotein receptor/ macrophage galactose lectin receptor) / CD301 is a Ca2+ dependent type II transmembrane lectin. In search for genes specifically expressed by dendritic cells (DC), we have cloned several cDNAs encoding different forms of asialoglycoprotein receptor (ASGPR), that were expressed in eukaryotic cells for use as immunogens. Immunoprecipitation from DCs using anti-DCASGPR mAb yields a major 40-kDa protein. mAb 125A10.03 recognized the ASGPR isoform expressed by DC but not the isoform expressed by monocytes. This antibody stained CD14+derived DCs obtained from CD34+ progenitors, but not the CD1a+derived subset. Accordingly, both monocyte-derived DCs and tonsillar interstitial-type DCs express DC-ASGPR protein, while Langerhans-type cells do not. DC-ASGPR is a feature of immaturity, as its expression is lost upon CD40L activation. In agreement with the presence of tyrosine-based and dileucine motifs in the intracytoplasmic domain, mAb against DC-ASGPR is rapidly internalized by DCs at 37°C. Finally, intracellular DC-ASGPR is localized in early endosomes, suggesting that the receptor recycles to the cell surface following internalization of ligand. (Valladeau J et al, 2001, J. Immunol., 167: 5767).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD301 / CLEC10A antibody

CD301 / CLEC10A Rat IgG2a ER-MP23 Biotin Ms F
0.1 mg / €420.00
  Acris Antibodies GmbH

CD301 / CLEC10A antibody

CD301 / CLEC10A Rat IgG2a ER-MP23 Low Endotoxin Ms C, F, FN
0.5 mg / €690.00
  Acris Antibodies GmbH

CD301 / CLEC10A antibody

CD301 / CLEC10A Rat IgG2a ER-MP23 Purified Ms C, F
0.25 mg / €470.00
  Acris Antibodies GmbH

CD301 / CLEC10A antibody

Predicted cell location: Cytoplasm. Positive control: Human liver cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CLEC10A antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x100) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD301 / CLEC10A (N-term) antibody

CLEC10A Antibody (N-term) (Cat. #AP50955PU-N) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CLEC10A antibody detected the CLEC10A protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CD301 / CLEC10A antibody

Western Blot analysis of CLEC10A expression in transfected 293T cell line (H00010462-T02) by CLEC10A MaxPab polyclonal antibody.

Lane 1: CLEC10A transfected lysate(34.76 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CD301 / CLEC10A antibody

CD301 / CLEC10A Mouse IgG2a 2D6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD301 / CLEC10A antibody

CD301 / CLEC10A Mouse IgG2a 1E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD301 / CLEC10A antibody

CD301 / CLEC10A Mouse IgG2a 2G12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CD301 / CLEC10A antibody

FACS analysisof monocyte-derivedDCs (GM+IL4) stainedwith 125A10.03+ goat anti-mouse FITC Mouse IgG1 125A10.03 Alexa Fluor 488 Hu F, ICC/IF
50 µg / €390.00
  Dendritics SAS

CD301 / CLEC10A antibody

FACS analysisof monocyte-derivedDCs (GM+IL4) stainedwith 125A10.03+ goat anti-mouse FITC Mouse IgG1 125A10.03 Alexa Fluor 488 Hu F, ICC/IF
0.1 mg / €520.00
  Dendritics SAS

CD301 / CLEC10A antibody

FACS analysisof monocyte-derivedDCs (GM+IL4) stainedwith 125A10.03+ goat anti-mouse FITC Mouse IgG1 125A10.03 Alexa Fluor 546 Hu ICC/IF
50 µg / €390.00
  Dendritics SAS

CD301 / CLEC10A antibody

FACS analysisof monocyte-derivedDCs (GM+IL4) stainedwith 125A10.03+ goat anti-mouse FITC Mouse IgG1 125A10.03 Alexa Fluor 546 Hu ICC/IF
0.1 mg / €520.00
  Dendritics SAS

CD301 / CLEC10A antibody

FACS analysisof monocyte-derivedDCs (GM+IL4) stainedwith 125A10.03+ goat anti-mouse FITC Mouse IgG1 125A10.03 Alexa Fluor 647 Hu F
50 µg / €390.00
  Dendritics SAS

CD301 / CLEC10A antibody

FACS analysisof monocyte-derivedDCs (GM+IL4) stainedwith 125A10.03+ goat anti-mouse FITC Mouse IgG1 125A10.03 Alexa Fluor 647 Hu F
0.1 mg / €520.00
  Dendritics SAS

CD301 / CLEC10A antibody

CD301 / CLEC10A Mouse IgG1 125A10.03 Biotin Hu IP
50 µg / €360.00
  Dendritics SAS

CD301 / CLEC10A antibody

CD301 / CLEC10A Mouse IgG1 125A10.03 Biotin Hu IP
0.1 mg / €480.00
  Dendritics SAS

CD301 / CLEC10A antibody

IHC staining of lung cryosection with 125A10.03 Mouse IgG1 125A10.03 Purified Hu C, F, FN, IP, WB
50 µg / €330.00
  Dendritics SAS

CD301 / CLEC10A antibody

IHC staining of lung cryosection with 125A10.03 Mouse IgG1 125A10.03 Purified Hu C, F, FN, IP, WB
0.1 mg / €440.00
  Dendritics SAS

CD301 / CLEC10A antibody

Monocyte-derived DC (GM+IL4) stained with 121A5.01+GAMFITC Mouse IgG1 121A5.01 Alexa Fluor 488 Hu F, ICC/IF
50 µg / €390.00
  Dendritics SAS

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