CD314 / KLRK1 antibody

Principal name

CD314 / KLRK1 antibody

Alternative names for CD314 / KLRK1 antibody

D12S2489E, NKG2D, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, Killer cell lectin-like receptor subfamily K member 1

SwissProt ID

O54709 (Mouse), O70215 (Rat), P26718 (Human), Q9GLF5 (Pig)

Gene ID

100528032 (KLRC4-KLRK1), 27007 (Klrk1), 24934, 22914 (KLRK1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit, Rat

Available applications

Flow Cytometry (F), Frozen Sections (C), Functional assay (FN), Immunoprecipitation (IP), Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of CD314 / KLRK1 antibody

CD314 is a homodimeric C-type lectin-like protein also known as NKG2D. It is expressed on NK cells, CD8+ T cells, ?/d T cells, and in vitro induced LAK cells. Several molecules have been identified as the ligands for NKG2D, including MHC class-I chain-related protein A (MICA), MICB, and UL16-binding proteins (ULBPs). NKG2D has no intrinsic signaling capacity, but attains this by non-covalent association with DAP10 or DAP12 adaptors. In addition to being a primary activation receptor on NK cells, NKG2D is also a costimulatory receptor for TCR-mediated T cell proliferation and cytokine production. The interaction of NKG2D with its ligands plays a role in the immune surveillance against pathogen and tumor cells, and in the pathogenesis of autoimmune diseases.

General readings

Hayakawa Y, Smyth MJ. Innate immune recognition and suppression of tumors. Adv Cancer Res. 2006;95:293-322

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD314 / KLRK1 antibody

  Goat Polyclonal Antibody against KLRK1  
TA303045 staining (0.3µg/ml) of human spleen lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD314 / KLRK1 antibody

  Rabbit polyclonal antibody to CD314 (killer cell lectin-like receptor subfamily K, member 1)  
NKG2D antibody [N3C2], Internal detects NKG2D protein at cytosol on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. NKG2D antibody [N3C2], Internal (TA308267) dilution: 1:250. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD314 / KLRK1 antibody

  Rat Anti-Mouse CD314 (NKG2D) Purified (50 ug)  
Two-color surface staining of mouse splenocytes with Anti-Mouse CD314 (NKG2D) PE and Anti-Mouse NK1.1 APC.  Total viable cells were used for analysis. Rat CX5 Purified Ms F
50 µg / €120.00
  OriGene Technologies, Inc.

CD314 / KLRK1 antibody

CD314 / KLRK1 Mouse IgG1 1D11 FITC Hu F
0.1 mg / €380.00
  Acris Antibodies GmbH

CD314 / KLRK1 antibody

CD314 / KLRK1 Mouse IgG1 1D11 FITC Hu F
25 µg / €190.00
  Acris Antibodies GmbH

CD314 / KLRK1 antibody

CD314 / KLRK1 Mouse IgG1 1D11 Low Endotoxin Hu C, F, FN, IP
0.5 mg / €540.00
  Acris Antibodies GmbH

CD314 / KLRK1 antibody

Staining of human peripheral blood lymphocytes with Mouse Anti Human CD314 (SM2260P/PT) Mouse IgG1 1D11 Purified Hu C, F, IP
0.2 mg / €480.00
  Acris Antibodies GmbH

CD314 / KLRK1 antibody

Staining of human peripheral blood lymphocytes with Mouse Anti Human CD314 (SM2260P/PT) Mouse IgG1 1D11 Purified Hu C, F, IP
25 µg / €180.00
  Acris Antibodies GmbH

CD314 / KLRK1 antibody

CD314 / KLRK1 Mouse IgG1 1D11 PE Hu F
100 Tests / €480.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD314 / KLRK1 (73-216, His-tag)

CD314 / KLRK1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CD314 / KLRK1 (73-216, His-tag)

CD314 / KLRK1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, KLRK1 (mGFP-tagged) - Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1), 200 uL, >10^7 TU/mL

Lenti ORF particles, KLRK1 (mGFP-tagged) - Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, KLRK1 (Myc-DDK tagged) - Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, KLRK1 (Myc-DDK tagged) - Human killer cell lectin-like receptor subfamily K, member 1 (KLRK1) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Klrk1 (GFP-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Klrk1 (GFP-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Klrk1 (Myc-DDK-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Klrk1 (Myc-DDK-tagged) - Mouse killer cell lectin-like receptor subfamily K, member 1 (Klrk1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Klrk1 (GFP-tagged ORF) - Rat killer cell lectin-like receptor subfamily K, member 1 (Klrk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Klrk1 (GFP-tagged ORF) - Rat killer cell lectin-like receptor subfamily K, member 1 (Klrk1), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Klrk1 (Myc-DDK-tagged ORF) - Rat killer cell lectin-like receptor subfamily K, member 1 (Klrk1), 200 uL, >10^7 TU/mL

Lenti ORF particles, Klrk1 (Myc-DDK-tagged ORF) - Rat killer cell lectin-like receptor subfamily K, member 1 (Klrk1), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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