CD32 / FcRII-a antibody

Principal name

CD32 / FcRII-a antibody

Alternative names for CD32 / FcRII-a antibody

Fc-gamma RII-a, Fc-gamma-RIIa, CDw32, FCGR2A, FCG2, FCGR2A1, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II, IgG Fc receptor II

SwissProt ID

P12318 (Human)

Gene ID

2212 (FCGR2A), 2213 (FCGR2B)

Available reactivities

Hu (Human), Can (Canine), Mky (Monkey), Por (Porcine), Rhesus Mky (Rhesus Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP), Flow Cytometry (F), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Functional assay (FN)

Background of CD32 / FcRII-a antibody

Low affinity IgG Fc receptor gamma II (Fc-gamma II), also known as CD32, is a member of the immunoreceptor tyrosine-based activating/inhibitory motif (ITAM/ITIM) family. Fc gamma receptors play a critical role in immunity by linking the IgG antibody mediated response with the regulatory functions of the immune system (1). Three classes of Fc gamma receptor exist; Fc gamma RI (CD64, a high affinity receptor), Fc gamma RII, and RIII (CD32 and CD16 respectively, both low affinity receptors). Fc gamma RIIa is an activating receptor, while RIIb1, RIIb2, and RIIb3 are inhibitory receptors generated by alternative splicing (1-2). Fc gamma RIIa is critical for antigen-presenting-cell activation and Fc gamma RIIb downregulates B-cell functions (3). Fc gamma RIIb has also been known to block the inflammatory immune response in mice (4). Once phosphorylated on tyrosine residues, Fc gamma RIIb associates with SHIP to downregulate phagocytosis.

General readings

McGaha TL, Sorrentino B, Ravetch JV. Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science. 2005 Jan 28;307(5709):590-3.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD32 antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-CD32 Antibody; followed by anti-mouse IgG PE. Mouse IgG2a Aff - Purified Hu F, ICC/IF
50 µl / €230.00
  Cohesion Biosciences Ltd.

CD32 antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-CD32 Antibody; followed by anti-mouse IgG PE. Mouse IgG2a Aff - Purified Hu F, ICC/IF
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CD32 antibody

Flow cytometric analysis of human peripheral blood lymphocytes using Anti-CD32 Antibody; followed by anti-mouse IgG PE. Mouse IgG2a Aff - Purified Hu F, ICC/IF
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500645) Mouse IgG1 OTI9C6 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500648) Mouse IgG2b OTI13D7 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FCGR2A mouse monoclonal antibody. (UM500050; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB59 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-FCGR2A mouse monoclonal antibody. (UM500051; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB60 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FCGR2A mouse monoclonal antibody. (UM500050; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB59 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-FCGR2A mouse monoclonal antibody. (UM500051; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB60 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human Ovary tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500646) Mouse IgG1 OTI13G9 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500647) Mouse IgG1 OTI19C10 Purified Hu F, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500649) Mouse IgG1 OTI6H7 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500651, Dilution 1:50) Mouse IgG1 OTI16E7 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500652) Mouse IgG1 OTI9G5 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500653) Mouse IgG2b OTI6D11 Purified Hu F, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500654) Mouse IgG1 OTI15G5 Purified Hu ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500667) Mouse IgG1 OTI16D6 Purified Hu F, ICC/IF, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-FCGR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500668) Mouse IgG1 OTI20D1 Purified Hu, Mky IP, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD32 / FcRII-a (full length) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2b 13D7 Purified Hu ICC/IF, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CD32 / FcRII-a antibody

Immunohistochemistry-Paraffin: FCGR2A Antibody (9G5) [NBP1-47735] - Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-FCGR2A mouse monoclonal antibody. (Dilution 1:50) Mouse 9G5 Aff - Purified Hu ICC/IF, IP, P, WB
0.1 ml / €530.00
  Novus Biologicals Inc.

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