CD322 / JAM2 antibody

Principal name

CD322 / JAM2 antibody

Alternative names for CD322 / JAM2 antibody

JAM-B, C21orf43, VEJAM, Junctional adhesion molecule B, Junctional adhesion molecule 2, Vascular endothelial junction-associated molecule

SwissProt ID

P57087 (Human), Q9JI59 (Mouse)

Gene ID

58494 (JAM2), 67374 (Jam2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of CD322 / JAM2 antibody

Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1.
Junctional adhesion molecule 2 (JAM2), also know as JAMB, is a member of the newly reported glycoprotein family of adhesion molecules found at intercellular junctions of endothelial cells and lymphocytes (human). In adult murine tissue JAM2 expression is restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.

General readings

Ueki T, Iwasawa K, Ishikawa H, Sawa Y,
Expression of junctional adhesion molecules on the human lymphatic endothelium.
Microvascular research 2008 Mar 75 (2): 269-78.
PMID: 17822725

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD322 / JAM2 antibody

  Rabbit Polyclonal antibody to JAM-B (junctional adhesion molecule 2)  
JAM-B antibody detects JAM2 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell lysate/extract. E. 30 ug BCL-1 whole Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD322 / JAM2 antibody

  Goat Anti-JAM2 / JAMB / CD322 Antibody  
TA305924 (0.5ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD322 / JAM2 antibody

  Rabbit Polyclonal Anti-JAM2 Antibody  
WB Suggested Anti-JAM2 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CD322 / JAM2 (29-299) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1G4 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

CD322 / JAM2 (Extracell. Dom.) antibody

CD322 / JAM2 Rat IgG1 2K15 Purified Ms WB
0.1 mg / €440.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

JAM2 - human gene knockout kit via CRISPR

JAM2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

JAM2 - human gene knockout kit via CRISPR

JAM2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

JAM2 - human gene knockout kit via CRISPR

JAM2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

JAM2 - human gene knockout kit via CRISPR

JAM2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jam2 - mouse gene knockout kit via CRISPR

Jam2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Jam2 - mouse gene knockout kit via CRISPR

Jam2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jam2 - mouse gene knockout kit via CRISPR

Jam2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Jam2 - mouse gene knockout kit via CRISPR

Jam2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CD322 / JAM2

  Purified recombinant protein of Human junctional adhesion molecule 2 (JAM2)  
CD322 / JAM2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

CD322 / JAM2 (21-238, His-tag)

CD322 / JAM2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CD322 / JAM2 (21-238, His-tag)

CD322 / JAM2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

JAM2 overexpression lysate

JAM2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, JAM2 (mGFP-tagged) - Human junctional adhesion molecule 2 (JAM2), 200 uL, >10^7 TU/mL

Lenti ORF particles, JAM2 (mGFP-tagged) - Human junctional adhesion molecule 2 (JAM2), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, JAM2 (Myc-DDK tagged) - Human junctional adhesion molecule 2 (JAM2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, JAM2 (Myc-DDK tagged) - Human junctional adhesion molecule 2 (JAM2) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Jam2 (GFP-tagged) - Mouse junction adhesion molecule 2 (Jam2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Jam2 (GFP-tagged) - Mouse junction adhesion molecule 2 (Jam2), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

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