CD326 / EPCAM / TACSTD1 antibody

Principal name

CD326 / EPCAM / TACSTD1 antibody

Alternative names for CD326 / EPCAM / TACSTD1 antibody

Ep-CAM, Epithelial cell adhesion molecule, GA733-2, EGP314, KSA, TROP1, Trop-1, M1S2, M4S1, MIC18, Tumor-associated calcium signal transducer 1, Major gastrointestinal tumor-associated protein GA733-2, Epithelial glycoprotein 314, Adenocarcinoma-associated antigen, KS 1/4 antigen

SwissProt ID

O55159, P16422 (Human), Q99JW5

Gene ID

4072 (EPCAM), 171577 (Epcam), 17075

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Mky (Monkey)

Available hosts

Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Luminex (LMNX)

Selected product citations ‐ of BM2274F

1. Mandair, D;Vesely, C;Ensell, L;Lowe, H;Spanswick, VJ;Hartley, J;Caplin, M;Meyer, T;2016A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours. Endocr. Relat. Cancer. PubMed PMID:  27521132.

Background of CD326 / EPCAM / TACSTD1 antibody

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Tissue specificity: This protein is expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinomas.
EPCAM: Epithelial Cell Adhesion Molecule (EpCAM) is a 40 kDa cell surface antigen. This antigen has been identified independently by a number of groups, and has been known by a variety of names. Several monoclonal antibodies have been raised against EpCAM, many of which have been described as tumour specific molecules on carcinomas. EpCAM is a Type 1 transmembrane glycoprotein. It is expressed on the basolateral membrane of cells by the majority of epithelial tissues, with the exception of adult squamous epithelium and some specific epithelial cell types including hepatocytes and gastric epithelial cells. EpCAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumour cells, and de novo expression being seen in dysplastic squamous epithelium. This cell surface, glycosylated 40kD protein is highly expressed in the bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin.

General readings

Muenz M., et al. (2004) Oncogene.23:5748-5758Muenz M., et al. (2005) Cancer Lett. 225:151-157

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD326 / EPCAM / TACSTD1 antibody

  anti-EpCAM mouse monoclonal antibody, clone OTI4G10 (formerly 4G10)  
CD326 / EPCAM / TACSTD1 Mouse IgM OTI4G10 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 HEA125 FITC Hu C, ICC/IF, P
0.25 ml / €420.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 ESA214 Purified Hu C, F, ICC/IF, P
1 ml / €360.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 ESA214 Purified Hu C, F, ICC/IF, P
0.5 ml / €270.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

CD326 / EPCAM / TACSTD1 Mouse IgG1 323/A3 Aff - Purified Hu F, ICC/IF, IP, P, WB
0.1 mg / €210.00
  Acris Antibodies GmbH

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody,clone UMAB131  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-EPCAM mouse monoclonal antibody. (UM500096; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB131 Purified Hu F, P, WB
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody,clone UMAB132  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-EPCAM mouse monoclonal antibody. (UM500097; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB132 Purified Hu P, WB
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody,clone UMAB131  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-EPCAM mouse monoclonal antibody. (UM500096; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB131 Purified Hu P, WB
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody,clone UMAB132  
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-EPCAM mouse monoclonal antibody. (UM500097; heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Mouse IgG1 UMAB132 Purified Hu P, WB
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

CD326 / EPCAM / TACSTD1 antibody

  Mouse Monoclonal anti-ESA/Ep-CAM Antibody  
Human Breast Carcinoma stained with anti-ESA_Ep-CAM antibody. Mouse IgG1 SPM491 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD326 / EPCAM / TACSTD1 antibody

  anti-EpCAM mouse monoclonal antibody, clone OTI2G1 (formerly 2G1)  
Anti-EpCAM mouse monoclonal antibody (TA500054) immunofluorescent staining of HeLa cells transiently transfected by  pCMV6-ENTRY EpCAM (RC201989) Mouse IgG1 OTI2G1 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  anti-EpCAM mouse monoclonal antibody, clone OTI2H9 (formerly 2H9)  
Immunofluorescent staining of HeLa cells using anti-EpCAM mouse monoclonal antibody (TA500056). Mouse IgG2a OTI2H9 Purified Hu ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EpCAM mouse monoclonal antibody, clone OTI2C8 (formerly 2C8)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-TACSTD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500171) Mouse IgM OTI2C8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTI1D4 (formerly 1D4)  
Immunofluorescent staining of HeLa cells using anti-EPCAM mouse monoclonal antibody (TA506619) at 1:100 dilution. Mouse IgG1 OTI1D4 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTIB1 (formerly B1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-EPCAM mouse monoclonal antibody at 1:500 dilution. (TA506626) Mouse IgG1 OTIB1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTI1H9 (formerly 1H9)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-EPCAM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506627) Mouse IgG2b OTI1H9 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTID7 (formerly D7)  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-EPCAM mouse monoclonal antibody at 1:500 dilution. (TA506628) Mouse IgG1 OTID7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTIC1 (formerly C1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-EPCAM mouse monoclonal antibody at 1:500 dilution. (TA506629) Mouse IgG2b OTIC1 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTIB8 (formerly B8)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-EPCAM mouse monoclonal antibody at 1:500 dilution. (TA506637) Mouse IgG2a OTIB8 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD326 / EPCAM / TACSTD1 antibody

  EPCAM mouse monoclonal antibody, clone OTI2A3 (formerly 2A3)  
Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-EPCAM mouse monoclonal antibody at 1:150 (TA506641) Mouse IgG1 OTI2A3 Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

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