CD332 / FGFR-2 antibody

Principal name

CD332 / FGFR-2 antibody

Alternative names for CD332 / FGFR-2 antibody

FGFR2, BEK, KGFR, KSAM, Fibroblast growth factor receptor 2, Keratinocyte growth factor receptor 2

SwissProt ID

P18461 (Chick), P21802 (Human), P21803 (Mouse)

Gene ID

2263 (FGFR2), 14183 (Fgfr2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Luminex (LMNX)

Background of CD332 / FGFR-2 antibody

Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally realted proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family if type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1to -4 are known. Multiple forms of FGFR-1 to -3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the ÿ isoform. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3, involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons, generate FGF receptors with alternative IgIII domains (IIIb and IIIc). A IIIa isoform which is a secreted FGF binding protein containing only the N-terminal half of the IgIII domain plus some intron sequences has also been reported for FGFR-1. Mutations in FGFR-1 to -3 have been found in patients with birth defects involving craniosynostosis.

General readings

McGrath M, Lee IM, Buring J, Hunter DJ, De Vivo I.
Novel breast cancer risk alleles and endometrial cancer risk.
Int J Cancer. 2008 Sep 10;123(12):2961-2964..
PMID: 18785201

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI3F8 (formerly 3F8)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FGFR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502799) Mouse IgG2a OTI3F8 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI5F7 (formerly 5F7)  
Anti-FGFR2 mouse monoclonal antibody (TA502829) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FGFR2(RC217098 ). Mouse IgG2a OTI5F7 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI5C5 (formerly 5C5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-FGFR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503137) Mouse IgG2b OTI5C5 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI1D3 (formerly 1D3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGFR2 (RC217098 , Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGFR2. Mouse IgG2b OTI1D3 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI1A11 (formerly 1A11)  
Cross-Reactivity of anti-FGFR2 (TA502798) with FGFR1 and FGFR3,not with FGFR4.HEK293T cells were transfected with the DDK(FLAG)-tagged DNAs of FGFR2 (RC217098),FGFR1(RC202080),FGFR3(RC215533),FGFR4(RC204230) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGFR2(TA502798).(1:500) and anti-DDK (1:2000), respectively. Mouse IgG2a OTI1A11 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI2D1 (formerly 2D1)  
Immunofluorescent staining of HeLa cells using anti-FGFR2 mouse monoclonal antibody (TA502843). Mouse IgG2a OTI2D1 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI3B3 (formerly 3B3)  
Cross-Reactivity of anti-FGFR2 (TA502877) with FGFR1 and FGFR3,not with FGFR4.HEK293T cells were transfected with the DDK(FLAG)-tagged DNAs of FGFR2 (RC217098),FGFR1(RC202080),FGFR3(RC215533),FGFR4(RC204230) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGFR2(TA502877).(1:500) and anti-DDK (1:2000), respectively. Mouse IgG2a OTI3B3 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI1H5 (formerly 1H5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-FGFR2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502919) Mouse IgG2a OTI1H5 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  FGFR2 mouse monoclonal antibody, clone OTI4D6 (formerly 4D6)  
Anti-FGFR2 mouse monoclonal antibody (TA503136) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY FGFR2(RC217098 ). Mouse IgG2b OTI4D6 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CD332 / FGFR-2 antibody

  Luminex and ELISA validated biotinylated FGFR2 mouse monoclonal antibody (clone 4D6), clone OTI4D6 (formerly 4D6)  
FGFR2 ELISA with 2D1 Capture (TA600368) and 4D6 Detection (TA700364) Antibodies. Substrate used: Recombinant Human FGFR2 (TP317098) Mouse IgG1 OTI4D6 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Luminex and ELISA validated biotinylated FGFR2 mouse monoclonal antibody (clone 3B3), clone OTI3B3 (formerly 3B3)  
FGFR2 ELISA with 5F7 Capture (TA600367) and 3B3 Detection (TA700365) Antibodies. Substrate used: Recombinant Human FGFR2 (TP317098) Mouse IgG1 OTI3B3 Purified Hu E, LMNX
50 µg / €345.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Goat Polyclonal Antibody against FGFR2  
TA303352 (0.3µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Anti-FGFR2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human ovarian cancer tissue. Recommended dilution: 1/5-20  The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using FGFR2 antibody at dilution 1/5, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Anti-FGFR2 Rabbit Polyclonal Antibody  
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA321070(FGFR2 Antibody)(left image) at dilution 1/20, the image on the right is treated with the synthetic peptide.(Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Rabbit polyclonal FGFR2 antibody  
Western blot analysis of extracts from A549 cells, using FGFR2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Rabbit anti-FGFR2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using FGFR2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Rabbit Polyclonal Anti-FGFR2 Antibody  
Western blot analysis on A549 cell lysate using FGFR2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Rabbit Polyclonal anti-FGFR-2 Antibody  
Human Breast Carcinoma stained with anti-FGFR-2 antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Rabbit Polyclonal FGFR2 Antibody  
ELISA: FGFR2 Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

CD332 / FGFR-2 antibody

  Luminex and ELISA validated FGFR2 mouse monoclonal antibody (clone 3B3, clone OTI3B3 (formerly 3B3)  
FGFR2 ELISA with 3B3 Capture (TA600364) and 4D6 Detection (TA700364) Antibodies. Substrate used: Recombinant Human FGFR2 (TP317098) Mouse IgG1 OTI3B3 Purified Hu E, LMNX
0.1 mg / €325.00
  OriGene Technologies, Inc.

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